Early recognition of pulmonary complications of sickle cell disease.
PMID 36634940 | PMCID PMC9987673 | DOI 10.15537/smj.2023.44.1.20220636 · Saudi medical journal · 2023
Sickle cell disease (SCD) is an inherited hematological disorder with multiple-organ involvement. The pulmonary complications of SCD are associated with significant morbidity and mortality. This article presents an important review of acute and chronic pulmonary complications, including acute chest syndrome, pneumonia, pulmonary thromboembolism, pulmonary fat embolism, chronic sickle cell lung disease, and pulmonary hypertension, in patients with SCD. Bronchial asthma and obstructive sleep apnea in relation to SCD are discussed in this article. Early recognition of pulmonary complications leads to early therapeutic interventions and improvement of the overall treatment outcome.
Validated evidence
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| phenotype | sickle cell disease | “Early recognition of pulmonary complications of sickle cell disease.” | 0.98 | phenotype_alias_lexicon_v2 |
| phenotype | hypertension | “This article presents an important review of acute and chronic pulmonary complications, including acute chest syndrome, pneumonia, pulmonary thromboembolism, pulmonary fat embolism, chronic sickle cell lung disease, and pulmonary hypertension, in patients with SCD.” | 0.98 | phenotype_alias_lexicon_v2 |
| phenotype | asthma | “Bronchial asthma and obstructive sleep apnea in relation to SCD are discussed in this article.” | 0.98 | phenotype_alias_lexicon_v2 |