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Gene profile

ENTPD1

HGNC:3363 · SaudiVarKB evidence summary derived from retained literature mentions.

2Gene mentions
2Publications
12Linked variants
3Associated phenotypes

Associated phenotypes

Co-mentioned in ENTPD1 publications
PhenotypeIdentifierArticlesMentions
intellectual disabilityHP:000124911
neurodevelopmental disorderHP:001275911
recurrent pregnancy loss11

Linked variants

Variants normalized to ENTPD1
VariantHGVS / rsIDArticlesMentions
c.398_399delinsAAc.398_399delinsAA11
p.Gly133Glup.Gly133Glu11
c.540delc.540del11
c.640delc.640del11
p.Leu62*p.Leu62*11
p.Gln323*p.Gln323*11
c.414-2_414-1delc.414-2_414-1del11
p.Tyr49Cysp.Tyr49Cys11
p.Leu370*p.Leu370*11
c.574-6_574-3delc.574-6_574-3del11
c.770_771delc.770_771del11
c.1041delc.1041del11

Population context

Reported in the same publications
Country / regionGroupCohortArticles
Not specified1621
Not specified271

Supporting publications

2 records
  1. 2024Impact of Vitamin D deficiency on immunological and metabolic responses in women with recurrent pregnancy loss: focus on VDBP/HLA-G1/CTLA-4/ENTPD1/adenosine-fetal-maternal conflict crosstalk.BMC pregnancy and childbirthPubMed ↗
  2. 2022Biallelic Variants in the Ectonucleotidase ENTPD1 Cause a Complex Neurodevelopmental Disorder with Intellectual Disability, Distinct White Matter Abnormalities, and Spastic Paraplegia.Annals of neurologyPubMed ↗