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Gene profile

LPL

HGNC:6677 · SaudiVarKB evidence summary derived from retained literature mentions.

17Gene mentions
17Publications
1Linked variants
7Associated phenotypes

Associated phenotypes

Co-mentioned in LPL publications
PhenotypeIdentifierArticlesMentions
diabetes mellitus55
obesityHP:000151333
coronary artery disease22
dyslipidemia22
hypertension11
pre-eclampsia11
thalassemiaHP:000187811

Linked variants

Variants normalized to LPL
VariantHGVS / rsIDArticlesMentions
rs28645722rs2864572211

Population context

Reported in the same publications
Country / regionGroupCohortArticles
Not specified01
Saudi Arabia1421
Not specified21
Saudi Arabia5201
Saudi Arabia · Jeddah941
Not specified6601

Supporting publications

17 records
  1. 2026Symptom and comorbidity burden in familial chylomicronemia syndrome: Impact on quality of life.Journal of clinical lipidologyPubMed ↗
  2. 2025Comparative evaluation of hypoxia preconditioned serum (HPS) and platelet-rich plasma (PRP) on preadipocyte survival and adipogenic differentiation.Frontiers in bioengineering and biotechnologyPubMed ↗
  3. 2024Effects of phytase enzyme supplementation on growth performance, intestinal morphology and metabolism in Nile tilapia (Oreochromis niloticus).Journal of animal physiology and animal nutritionPubMed ↗
  4. 2024Bacoside-A repressed the differentiation and lipid accumulation of 3T3-L1 preadipocytes by modulating the expression of adipogenic genes.Biotechnology and applied biochemistryPubMed ↗
  5. 2023Luteolin-7-O-rutinoside Protects RIN-5F Cells from High-Glucose-Induced Toxicity, Improves Glucose Homeostasis in L6 Myotubes, and Prevents Onset of Type 2 Diabetes.MetabolitesPubMed ↗
  6. 2023Ameliorating effect of probiotic on nonalcoholic fatty liver disease and lipolytic gene expression in rabbits.Scientific reportsPubMed ↗
  7. 2022Ocimum basilicum L. Methanol Extract Enhances Mitochondrial Efficiency and Decreases Adipokine Levels in Maturing Adipocytes Which Regulate Macrophage Systemic Inflammation.Molecules (Basel, Switzerland)PubMed ↗
  8. 2021Coronary Artery Disease: Association Study of 5 Loci with Angiographic Indices of Disease Severity.Disease markersPubMed ↗
  9. 2021Synthesis of Ziziphus spina-christi (Jujube) Root Methanol Extract Loaded Functionalized Silver Nanoparticle (ZS-Ag-NPs); Physiochemical Characterization and Effect of ZS-Ag-NPs on Adipocyte Maturation, Adipokine and Vascular Smooth Muscle Cell Interaction.Nanomaterials (Basel, Switzerland)PubMed ↗
  10. 2020Association of Four Missense SNPs with Preeclampsia in Saudi Women.Saudi journal of medicine & medical sciencesPubMed ↗
  11. 2019Pumpkin (Cucurbita ficifolia Bouché) extract attenuate the adipogenesis in human mesenchymal stem cells by controlling adipogenic gene expression.Saudi journal of biological sciencesPubMed ↗
  12. 2018Actin depolymerization enhances adipogenic differentiation in human stromal stem cells.Stem cell researchPubMed ↗
  13. 2018Association of apolipoprotein E gene polymorphisms with blood lipids and their interaction with dietary factors.Lipids in health and diseasePubMed ↗
  14. 2018The application of gene marker-assisted selection and proteomics for the best meat quality criteria and body measurements in Qinchuan cattle breed.Molecular biology reportsPubMed ↗
  15. 2017High fat diet modifies the association of lipoprotein lipase gene polymorphism with high density lipoprotein cholesterol in an Asian Indian population.Nutrition & metabolismPubMed ↗
  16. 2017Exome-wide association study of plasma lipids in >300,000 individuals.Nature geneticsPubMed ↗
  17. 2016Origanum Majoranum Extract Modulates Gene Expression, Hepatic and Renal Changes in a Rat Model of Type 2 Diabetes.Iranian journal of pharmaceutical research : IJPRPubMed ↗