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Gene profile

SCNN1A

HGNC:10599 · SaudiVarKB evidence summary derived from retained literature mentions.

4Gene mentions
4Publications
9Linked variants
1Associated phenotypes

Associated phenotypes

Co-mentioned in SCNN1A publications
PhenotypeIdentifierArticlesMentions
hypertension11

Linked variants

Variants normalized to SCNN1A
VariantHGVS / rsIDArticlesMentions
c.729_730delAGc.729_730delAG11
c.1496A>Gc.1496A>G11
p.Q499Rp.Q499R11
c.1453C>Tc.1453C>T11
p.Q485Xp.Q485X11
c.1322_1322delAc.1322_1322delA11
p.N441Tfsp.N441Tfs11
p.I68Tfsp.I68Tfs11
c.1522C>Tc.1522C>T11

Population context

Reported in the same publications
Country / regionGroupCohortArticles
Saudi Arabia1
Saudi Arabia221

Supporting publications

4 records
  1. 2024Pseudohypoaldosteronism Type 1b in a Saudi Female Infant Due to Homozygous Variant Gene Mutation in SCNN1A: A Case Report.CureusPubMed ↗
  2. 2022A Novel SCNN1A Variation in a Patient with Autosomal-recessive Pseudohypoaldosteronism Type 1.Journal of clinical research in pediatric endocrinologyPubMed ↗
  3. 2021A Unique Genotype of Pseudohypoaldosteronism Type 1b in a Highly Consanguineous Population.Journal of the Endocrine SocietyPubMed ↗
  4. 2021A Rare Case of Familiar Hypertension Presenting with Hypertensive Encephalopathy in an Elderly Patient: A Diagnostic Dilemma: A Presentation of Liddle's Syndrome due to Novel Mutation in SCNN1G Gene.Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi ArabiaPubMed ↗