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Gene profile

CAPN3

HGNC:1480 · SaudiVarKB evidence summary derived from retained literature mentions.

6Gene mentions
6Publications
1Linked variants
4Associated phenotypes

Associated phenotypes

Co-mentioned in CAPN3 publications
PhenotypeIdentifierArticlesMentions
congenital myopathy22
coronary artery disease11
Duchenne muscular dystrophy11
Pompe disease11

Linked variants

Variants normalized to CAPN3
VariantHGVS / rsIDArticlesMentions
3A>G11

Population context

Reported in the same publications
Country / regionGroupCohortArticles
Saudi Arabia1
Saudi Arabia1
Saudi Arabia1121
Not specified111
Not specified8,2631

Supporting publications

6 records
  1. 2022A recurrent rare intronic variant in CAPN3 alters mRNA splicing and causes autosomal recessive limb-girdle muscular dystrophy-1 in three Pakistani pedigrees.American journal of medical genetics. Part A1 mentions
  2. 2021Clinical and genetic features of Calpainopathies in Saudi Arabia - a descriptive cross-sectional study.European review for medical and pharmacological sciences1 mentions
  3. 2017The sensitivity of exome sequencing in identifying pathogenic mutations for LGMD in the United States.Journal of human genetics1 mentions
  4. 2017Novel genetic loci associated with long-term deterioration in blood lipid concentrations and coronary artery disease in European adults.International journal of epidemiology1 mentions
  5. 2016A first-line diagnostic assay for limb-girdle muscular dystrophy and other myopathies.Human genomics1 mentions
  6. 2016Novel Homozygous Missense Mutation in CAPN3 Gene Detected in a Saudi Arabian Family With Limb-Girdle Muscular Dystrophy Type 2A.Journal of clinical neuromuscular disease1 mentions