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Gene profile

HMGCL

HGNC:5005 · SaudiVarKB evidence summary derived from retained literature mentions.

4Gene mentions
4Publications
2Linked variants
2Associated phenotypes

Associated phenotypes

Co-mentioned in HMGCL publications
PhenotypeIdentifierArticlesMentions
epilepsyHP:000125011
developmental delayHP:000126311

Linked variants

Variants normalized to HMGCL
VariantHGVS / rsIDArticlesMentions
c.122G>Ac.122G>A11
p.Arg41Glnp.Arg41Gln11

Population context

Reported in the same publications
Country / regionGroupCohortArticles
Saudi Arabia1
Saudi Arabia · Riyadh501
Saudi Arabia931
Saudi Arabia621

Supporting publications

4 records
  1. 2022HMG-CoA Lyase Deficiency: A Retrospective Study of 62 Saudi Patients.Frontiers in genetics1 mentions
  2. 2021Hepatic Manifestations of 3-Hydroxy-3-Methylglutaryl-Coenzyme-A Lyase Deficiency in Saudi Patients: Experience of a Tertiary Care Center.Journal of pediatric genetics1 mentions
  3. 2007Molecular genetics of HMG-CoA lyase deficiency.Molecular genetics and metabolism1 mentions
  4. 2006Mutations underlying 3-hydroxy-3-methylglutaryl CoA lyase deficiency in the Saudi population.BMC medical genetics1 mentions