GSTP1
HGNC:4638 · 28 retained evidence mentions
Source-grounded findings
Supporting evidence
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | GSTP1 | “Molecular dynamics investigation of single nucleotide polymorphism-driven variations in GSTP1 phosphorylation and substrate interaction.” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “Molecular Characterization and Impact of the Genetic Variants GSTP1, LncRNA H19, TCF7L2 and HNF1A on the Risk of Coronary Artery Disease With and Without T2DM Comorbidity: A Genomic Biomarker Study.” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “The Influence of CYP2B6, GSTP1, and SLCO1B1 Star Allele-Predicted Phenotypes and CBR1 Genetic Variants on Effectiveness Outcomes in Patients With Hepatocellular Carcinoma Receiving Doxorubicin via Transarterial Chemoembolization.” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “Investigation of GSTP1 and PTEN gene polymorphisms and their association with susceptibility to colorectal cancer.” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “Exposure to heavy metals, antioxidant status, and the interaction of single nucleotide polymorphisms in the genes CAT rs7943316, GSTP1 rs1695, as well as GSTM1 and GSTT1 genes, among workers in occupational settings.” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “Chronic exposure to electronic waste poses risk to liver toxicity with molecular interaction of GSTM1, GSTT1 null variants, and GSTP1.” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “Platinum-induced ototoxicity in pediatric cancer survivors: GSTP1 c.313A>G variant association.” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “The current study aimed to investigate the relationship between polymorphisms in detoxifying (GSTM1, GSTT1, and GSTP1) genes and their association with colorectal cancer (CRC) in tobacco addicts of Pashtun ethnicity.” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “Single-nucleotide polymorphisms (SNPs) of antioxidant enzymes SOD2 and GSTP1 genes and SLE risk and severity in an Egyptian pediatric population.” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “GSTM1, GSTP1, and GSTO1 SNPs showed no significant association (p > 0.05).” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “Association of GSTP1 p.Ile105Val (rs1695, c.313A > G) Variant with the Risk of Breast Carcinoma among Egyptian Women.” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “GSTP1 variant genotypes AG (OR = 2.1, P = .003) and GG (OR = 5.6, P < .001), significantly associated with increased risk of CML.” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “Genetic Polymorphism of GSTP1, GSTM1 and GSTT1 Genes and Susceptibility to Chronic Myeloid Leukaemia.” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “GSTP1 involved in the metabolism of carcinogens and toxins, reduces damage of DNA and act as a suppressor of carcinogenesis.” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “In the GST gene, GSTM1 and GSTT1 variants were genotyped by multiplex PCR, and GSTP1 variants were genotyped by PCR-RFLP analysis.” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “The prognostic impact of GSTM1/GSTP1 genetic variants in bladder Cancer.” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “Association Of GSTM1, GSTT1 And GSTP1 Polymorphisms With Breast Cancer Among Jordanian Women.” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “Promoter methylation and Ile105val polymorphism of GSTP1 gene in the modulation of colorectal cancer risk in ethnic Kashmiri population.” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “Association of GSTP1 and ERCC1 polymorphisms with toxicity in locally advanced head and neck cancer platinum-based chemoradiotherapy treatment.” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “Polymorphisms and mutations in GSTP1, RAD51, XRCC1 and XRCC3 genes in breast cancer patients.” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “The objective of our study was to evaluate the oxidative stress profile caused by IR in 29 Tunisian medical staff from radiology and radiotherapy departments, and to find an association between the GSTM1 null, GSTT1 null, and GSTP1 Ile105Val polymorphisms and oxidative stress biomarkers.” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “Does Val/Val genotype of GSTP1 enzyme affects susceptibility to colorectal cancer in Saudi Arabia?” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “In a case-control study, we investigated the role of GSTP1 Ile105Val polymorphism in predisposition to T2DM in patients from Tarabah province, Saudi Arabia.” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “Association between GSTP1 genotypes and hormone receptor phenotype in invasive ductal carcinomas of breast.” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “The GSTP1 Ile105Val polymorphism is not associated with susceptibility to colorectal cancer.” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “METHODS: 223 incident papillary thyroid cancer cases and 513 controls recruited from Saudi Arabian population were analyzed for the association between polymorphisms in genes encoding folic acid metabolizing enzymes MTHFR and six xenobiotics-metabolizing enzymes including CYP1A1 T3801C, C4887A, GSTP1 A1578G, C2293T, GSTM1, GSTT1, NAT2 G590A, NQO*1 C609T, using PCR-RELP.” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “Polymorphisms in five genes (CYP1A1, GSTT1, GSTP1, GSTM1, and NQO1) were characterized in 182 individuals with DLBCL and 513 normal controls using PCR-RFLP method.” | 0.98 | hgnc_dict_v1 |
| gene | GSTP1 | “The frequencies of alleles and/or genotypes for CYP1A1*2A, GSTT1 null, GSTT1 and GSTM1 double null, and GSTP1 A1578G in Arabs were significantly higher than those reported in Caucasians.” | 0.98 | hgnc_dict_v1 |