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Gene profile

SORL1

HGNC:11185 · SaudiVarKB evidence summary derived from retained literature mentions.

4Gene mentions
4Publications
7Linked variants
2Associated phenotypes

Associated phenotypes

Co-mentioned in SORL1 publications
PhenotypeIdentifierArticlesMentions
Alzheimer disease44
Parkinson disease11

Linked variants

Variants normalized to SORL1
VariantHGVS / rsIDArticlesMentions
p.Val297Metp.Val297Met11
p.Arg1084Cysp.Arg1084Cys11
p.Asp1100Asnp.Asp1100Asn11
p.Pro1213Serp.Pro1213Ser11
p.Glu380Lysp.Glu380Lys11
G1135T11
p.G379Wp.G379W11

Population context

Reported in the same publications
Country / regionGroupCohortArticles
Saudi Arabia1171

Supporting publications

4 records
  1. 2024Genome-wide association neural networks identify genes linked to family history of Alzheimer's disease.Briefings in bioinformaticsPubMed ↗
  2. 2021Molecular Genetics of Early- and Late-Onset Alzheimer's Disease.Current gene therapyPubMed ↗
  3. 2021SORL1 mutation in a Greek family with Parkinson's disease and dementia.Annals of clinical and translational neurologyPubMed ↗
  4. 2019Genetic Study of Alzheimer's Disease in Saudi Population.Journal of Alzheimer's disease : JADPubMed ↗