Population record
· 91 retained evidence mentions
Source-grounded findings
Supporting evidence
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| population | Population | “We describe 3 children with genetically confirmed ATS who demonstrated strikingly different clinical courses.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Breast cancer is a leading cause of cancer-related morbidity and mortality globally, with the WHO reporting approximately 2.3 million new cases and 685,000 deaths annually.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “BACKGROUND: Breast cancer (BC) is a highly heterogeneous malignancy originating from mammary epithelial cells and remains a leading cause of cancer-related mortality worldwide, with ∼2.3 million new cases and over 665,000-670,000 deaths annually.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “However, whether and how arbuscular mycorrhizal (AM) fungi mediate the entire 14-3-3 gene family to enhance drought tolerance in woody fruit crops remains unclear.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Furthermore, understanding the tumor-associated biological functions of 14-3-3 family proteins and targeting their interaction with specific miRNAs or directly manipulating 14-3-3 proteins may reveal their potential for cancer treatment in the future, as discussed in this review.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Overall, 3 patients (42.9%) were seizure-free at the final follow-up.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “BACKGROUND: Recessive loss-of-function NARS2 variants causing the multi-system disorder Combined oxidative phosphorylation deficiency 24 (COXPD24) have recently been reported in 3 individuals with diabetes diagnosed between 3 days and 14 months of age.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “RESULTS: We studied 3 individuals from an extended kindred presenting with a spectrum of infections, lymphoproliferation, and autoimmune manifestations.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “The diagnosis was confirmed by clinical exome sequencing, which demonstrated a homozygous missense variant in exon 3 of the solute carrier family 39 member 4 (SLC39A4) gene.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Further in silico validation analyses revealed increased gene expression of galectin-3 in DM TNBC patients, resulting in poor overall survival and disease-free survival.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “In 2020, an estimated 2.3 million new cases were reported, resulting in approximately 685,000 deaths.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “The BC represents 11.7% of all cancer cases and accounts for a predestined 2.3 million new cases.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “METHODS: During the Fall semester of the 2023-2024 academic term, third-year student pharmacists completed 3 pharmacogenetic counseling cases focused on cardiovascular conditions, psychiatry, and epilepsy-using PharmTutorAI.com.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Patients with SA were categorized into 3 cohorts, those with: (i) no prescription for OCS, (ii) prescription(s) for iOCS (ie, ≤90 days in previous 12-months, usually short courses for exacerbations), and (iii) prescriptions for LTOCS (ie, >90 days in previous 12-months).” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Colonization was associated with an increased risk of infection in the 3 cohorts (CRE, MRSA, and VRE), with risk ratios reported as 4.6, 8.2, and 22, respectively.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “The UV-irradiated SH20 variant boosted shoot length up to 3 times that of the control.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “The control group was fed a basal diet only, while the other 3 were administered control diets supplemented with P. polymyxa at 3 concentrations: 0.5, 1, and 1.5 mg/kg.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Only 3 cases of melanocytic lesions in the middle ear have been reported.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Two novel homozygous variants of ATP6V0A2 and ALDH18A1 lead to autosomal recessive cutis laxa type 2 and 3 in two Pakistani families.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “However, CyP3A5*3 heterozygous individuals did not show any significant difference in comparison to CyP3A5*1/*3 individuals.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “METHODS: This case-controlled study included 3 subject groups: twenty healthy females (control group), twenty PCOS females before treatment, and twenty PCOS females treated with metformin at a dose (500 mg 3 times per day for 3 months).” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Here, we identified biallelic variants in the highly conserved flightless-I (FLII) gene in 3 families with idiopathic, early-onset dilated CM.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Inhibin-Positive "Cholangioblastic" Variant of Intrahepatic Cholangiocarcinoma: Report of 3 New Patients With Review of the Literature.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Breast carcinoma has surpassed lung carcinoma and currently represents the chief type of cancer diagnosed (2.3 million new cases, which amount to 11.7% of all cancer cases).” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Drug-resistant epilepsy, defined as the failure of 2 or more antiseizure medications to achieve seizure freedom, is responsible for 2/3 of epilepsy cases.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Breast cancer (BC) is the most common cancer in women worldwide, with 2.3 million cases recorded in 2020.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Methods: A cross-sectional study was conducted for 3 months among patients attending diabetes mellitus outpatient clinic in Irbid, Jordan.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Interestingly, restlessness and restless leg syndrome, nocturnal dyspnea, narcolepsy and bruxism were reported in 7, 6, 5, 4 and 3 cases, respectively.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Distinct homozygous mutations in CBLB were identified in 3 unrelated children with early-onset autoimmunity, one of whom also had chronic urticaria.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Primary adrenal MRT is extremely rare, with only 3 cases reported in the literature.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “In the case series, we discuss 3 patients with challenging LAA anatomy that underwent successful Watchman FLX implantation.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Finally, group A (treatment group on day 3 of differentiation and control group on day 0 of differentiation) obtained a total of 1180 mRNA and 185 lncRNA; group B (treatment group on day 6 of differentiation and control group on day 0 of differentiation).” | 0.80 | saudi_context_rules_v1 |
| population | Population | “All but 3 patients had normal renal and cardiac function at the time of transplantation.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “We report a new FFH type-3 patient who underwent unnecessary parathyroidectomy in association with misleading FCH-PET/CT imaging.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “According Global Cancer Statistics 2020 GLOBOCAN estimates female breast cancer was found as the most commonly diagnosed cancer, with an estimated 2.3 million new cases (11.7%), and the fourth leading cause (6.9%) of cancer death among women worldwide.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “The author will demonstrate that the rationale behind the L1-3 classification in patients in VA is based on the embryogenesis of the 6 affected anatomical areas in VA.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Moreover, bilateral peripheral facial paralysis associated with SS has been described only in 3 patients in the literature and the first case was described by Henrik Sjogren himself in 1935.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “CASE REPORT Herein, we report 3 cases of pyogenic liver abscesses complicated by pleural empyema, each approached differently, along with a succinct review of the literature.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “In addition to a high-dose oral steroid, azathioprine was given for 3 months before the patient developed decompensated liver failure, which was successfully managed with a liver transplant.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Clopidogrel is widely used in these patients in several areas worldwide, such as Middle East, but is associated to sub-optimal platelet inhibition in up to 1/3 of treated patients.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “PRESENTATION OF CASE: We reported a case of a 3 day old male newborn who presented with failure to pass meconium along with progressive abdominal distension.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “CASE REPORT A series of 3 patients with histopathologically-proven biopsy specimens of XP-associated neoplasia of the eyelids and ocular surface underwent subconjunctival injections of PEG-IFN-alpha-2 band topical cycles of MMC.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “To date, 80 missense mutations have been identified in association with the Aldehyde Dehydrogenase 3 Family Member A2 (ALDH3A2) gene causing SLS.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “In this study, we report a family of 4 (a father with 3 children) who presented with congenital hypoparathyroidism and hypocalcemia, facial asymmetry, deafness, normal intelligence, and no cardiac involvement.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Furthermore, we evaluated the add-on effect of combined use of low Pioglitazone dose of and ω-3 on reproductive functions in adult male T2DM rats.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “This study investigates the effects of an intraverbal webbing procedure on the development of divergent and convergent intraverbal responses in 3 children with autism spectrum disorder between the ages of 4 and 7 years using a multiple-probe across-participants design.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “It is concluded that CD8+ T cells show a reduced response to HPIV-3 in children with severe LRTIs suggesting a strong association of these cells with disease severity.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Surgical mitral valve replacement using direct implantation of Sapien 3 valve in a patients with severe mitral annular calcification without adjunctive techniques, a case report.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Supraventricular tachycardias, conduction disease, and cardiomyopathy in 3 families with the same rare variant in TNNI3K (p.Glu768Lys).” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Usually, the seizures were brief lasting <3 min but few patients also presented with status epilepticus especially when the medication was weaned.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “In the present study, we assessed the role of TIM-3 signaling in children with ASD.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Acute Intermittent Porphyria: A Report of 3 Cases with Neuropathy.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “We matched them with 3 CI patients each with normal cochlear morphology regarding sex, age, side, implant type and surgical date.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “RESULTS: Five patients from 3 independent families presented at ages ranging from 32 to 52 years with neurologic symptoms that included progressive hypophonia, upper and lower limb weakness and spasticity, and cerebellar dysfunction and MRIs characterized by widespread white matter alterations.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “KIF1Bβ is a kinesin-3 family anterograde motor protein essential for neuronal development, viability, and function.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “LDL-C cut points were determined from a large database comprising > 3.3 million subjects.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “The aim of this study was to examine the sialidosis type 1 brain using volumetric magnetic resonance imaging (MRI), diffusion tensor imaging and functional MRI in comparison to 3 controls.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “We present 3 children with homozygous null variants in the PPP1R21 gene.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “RESULTS: Among ~2,500 women with SLE, we found 3 patients with a triple mosaic, consisting of 45,X/46,XX/47,XXX.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “There are only 3 case reports of GSS in China.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “A New IVH Scoring System Based on Laterality Enhances Prediction of Neurodevelopmental Outcomes at 3 Years Age in Premature Infants.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Here, we identified recessive mutations in the gene encoding the actin-binding protein advillin (AVIL) in 3 unrelated families with SRNS.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “METHODS: The pedigree included 3 generations of a family with 13 affected individuals.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Tumor and treatment characteristics were then compared among the first five groups (only 3 patients were allocated to G6).” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Genetic analysis of Xp22.3 micro-deletions in seventeen families segregating isolated form of X-linked ichthyosis.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “OBJECTIVE: To report and discuss the multi-domain impact of elosulfase alfa, with focus on tertiary and composite endpoints, in the 24-week, randomized, double-blind, placebo-controlled phase 3 trial in patients with Morquio A syndrome (mucopolysaccharidosis IVA).” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Upregulated hepatic expression of mitochondrial PEPCK triggers initial gluconeogenic reactions in the HCV-3 patients.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Phase 2 and 3 clinical trials in patients with moderate and severe hypercholesterolemia (including FH) show that this approach is safe and highly efficacious to lower LDL-C and lipoprotein(a).” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Recently, 3 unrelated children with a potentially novel 3q26.33-3q27.2 microdeletion syndrome were reported.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “We report 3 recent autopsy cases that illustrate the clinicopathologic distinction between the 3 entities.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “When specifically questioned, the 3 affected children had experienced recurrent bouts of diarrhea in early childhood, which is a common feature of the disease.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Iris neovascularization and neovascular glaucoma in neurofibromatosis type 1: report of 3 cases in children.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “At 12-18 months, 1 woman in the balloon and 3 in the control group were not trying to conceive and 1 in each group had not conceived.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “RESULTS: We have identified a novel Xq12-q13.3 duplication in an extended family.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “During a follow-up of 41.2 ± 17.6 months, 3 patients (all with prior cardiac arrest) had appropriate device therapy.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Only 3 cases of mesenteric EOS have been reported in English literature.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Linkage and haplotype analysis for chemokine receptors clustered on chromosome 3p21.3 and transmitted in family pedigrees with asthma and atopy.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Based on the findings in the second symptomatic child, NR2E3 analysis was performed, which revealed homozygosity for a novel mutation, p.S44X, in all 3 affected individuals and heterozygosity for the mutation in both asymptomatic individuals.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “We report a homozygous novel mutation (c.93 delG) in the ARG1 gene from 3 affected children of a Pakistani family living in the United Arab Emirates.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “We report 3 patients with NB, whose main complaint was sensorineural hearing loss (SNHL) who were followed up at our hospital for 3 years.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “This report describes the first 3 children with Angelman syndrome from Bahrain.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “World Health Organization and UNAIDS unveil plan to get 3 million AIDS patients on treatment by 2005.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “We report 3 patients with CLD associated with various renal abnormalities including chronic renal failure secondary to renal hypoplasia, nephrocalcinosis and congenital nephrotic syndrome.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Complications of cerebral palsy, mental retardation and epilepsy occurred in 3 patients (23%).” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Complications of cerebral palsy, mental retardation and epilepsy occurred in 3 patients (23%).” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Molecular analyses of the GSS gene was performed in 3 patients.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “The total number of seizures ranged between 3 and 10 (mean 5), and all seizures resolved by day 3 in all cases.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Our case is compared to 3 similar cases of t(5p;21q) reported recently, which were also originally diagnosed as monosomy 21.” | 0.80 | saudi_context_rules_v1 |
| population | Population | “Jaundice and pruritus were early symptoms, with onset in the 1st 3 months in all patients.” | 0.80 | saudi_context_rules_v1 |