FOXP3
HGNC:6106 · SaudiVarKB evidence summary derived from retained literature mentions.
22Gene mentions
22Publications
3Linked variants
12Associated phenotypes
Associated phenotypes
Co-mentioned in FOXP3 publications| Phenotype | Identifier | Articles | Mentions |
|---|---|---|---|
| diabetes mellitus | — | 2 | 2 |
| autism spectrum disorder | HP:0000729 | 2 | 2 |
| neurodevelopmental disorder | HP:0012759 | 2 | 2 |
| asthma | — | 2 | 2 |
| leukemia | — | 1 | 1 |
| epilepsy | HP:0001250 | 1 | 1 |
| hypertension | — | 1 | 1 |
| pre-eclampsia | — | 1 | 1 |
| atopic dermatitis | — | 1 | 1 |
| renal failure | — | 1 | 1 |
| colorectal cancer | — | 1 | 1 |
| breast cancer | — | 1 | 1 |
Linked variants
Variants normalized to FOXP3| Variant | HGVS / rsID | Articles | Mentions |
|---|---|---|---|
| p.Arg347His | p.Arg347His | 1 | 1 |
| rs2232365 | rs2232365 | 1 | 1 |
| c.1222G>A | c.1222G>A | 1 | 1 |
Population context
Reported in the same publications| Country / region | Group | Cohort | Articles |
|---|---|---|---|
| Saudi Arabia | — | — | 1 |
| Not specified | — | 20 | 1 |
| Not specified | — | 22 | 1 |
| Not specified | — | 200 | 1 |
| Not specified | — | 67 | 1 |
| Not specified | — | 46 | 1 |
| Not specified | — | 73 | 1 |
Supporting publications
22 records- 2026X-Linked immune dysregulation, polyendocrinopathy, and enteropathy (IPEX) syndrome with concurrent membranous and IgA nephropathy: a case report.BMC nephrologyPubMed ↗
- 2026Understanding the Molecular Landscape of Alopecia Areata: Key Genes, Regulatory Networks, and Therapeutic Targets.Health science reportsPubMed ↗
- 2026Unveiling natural anti-inflammatory compounds for sinusitis treatments by modulating FOXP3, C5aR1, and LIF.Frontiers in immunologyPubMed ↗
- 2026Precision Immunoregulation in transplantation: The rise of engineered Treg therapies.Molecular biology reportsPubMed ↗
- 2025CD4+ T-cell Subsets and Cytokine Signature in Pemphigus Foliaceus Clinical Stratification beyond the th1/Th2 Paradigm.Current molecular medicinePubMed ↗
- 2025Biochemical investigation of FOXP3 genetic polymorphism and its association with biochemical parameters in pre-eclampsia patients.Naunyn-Schmiedeberg's archives of pharmacologyPubMed ↗
- 2025Cullin-3 and Regulatory Biomolecules Profiling in Vitiligo: Integrated Docking, Clinical, and In Silico Insights.BiomoleculesPubMed ↗
- 2025Crosstalk Between Immunity and Oncogenes Within the Tumor Microenvironment of HPV-Associated Cervical Squamous Cell Carcinoma.OncoTargets and therapyPubMed ↗
- 2025Profiling of Breast Cancer Stem Cell Types/States Shows the Role of CD44hi/CD24lo-ALDH1hi as an Independent Prognostic Factor After Neoadjuvant Chemotherapy.International journal of molecular sciencesPubMed ↗
- 2025Gut microbiota alterations and their association with tumorigenic pathways in colorectal cancer: insights from a pooled analysis of 109 microbiome datasets.Gut pathogensPubMed ↗
- 2024New insights on genetic variants and phenotypic features of childhood large-vessel vasculopathy: a systematic review and single-centre series.Clinical and experimental rheumatologyPubMed ↗
- 2024Investigating the T regulatory cells and Sirtuin-I serum level in immunotherapy treated house dust mite allergic asthma patients.The Journal of asthma : official journal of the Association for the Care of AsthmaPubMed ↗
- 2024Regulatory T-cell dysfunction and cutaneous exposure to Staphylococcus aureus underlie eczema in DOCK8 deficiency.The Journal of allergy and clinical immunologyPubMed ↗
- 2024Activated PI3Kδ Specifically Perturbs Mouse Regulatory T Cell Homeostasis and Function Leading to Immune Dysregulation.Journal of immunology (Baltimore, Md. : 1950)PubMed ↗
- 2024Therapeutic Efficacy of Lavandula dentata's Oil and Ethanol Extract in Regulation of the Neuroinflammation, Histopathological Alterations, Oxidative Stress, and Restoring Balance Treg Cells Expressing FoxP3+ in a Rat Model of Epilepsy.Pharmaceuticals (Basel, Switzerland)PubMed ↗
- 2022Anti-inflammatory and immunomodulatory activity of Mangifera indica L. reveals the modulation of COX-2/mPGES-1 axis and Th17/Treg ratio.Pharmacological researchPubMed ↗
- 2021Dysregulation of Ki-67 Expression in T Cells of Children with Autism Spectrum Disorder.Children (Basel, Switzerland)PubMed ↗
- 20215-Aminoisoquinolinone, a PARP-1 Inhibitor, Ameliorates Immune Abnormalities through Upregulation of Anti-Inflammatory and Downregulation of Inflammatory Parameters in T Cells of BTBR Mouse Model of Autism.Brain sciencesPubMed ↗
- 2021Familial Clustering of Juvenile Psoriatic Arthritis Associated with a Hemizygous FOXP3 Mutation.Current rheumatology reportsPubMed ↗
- 2021Case Report: FOXP3 Mutation in a Patient Presenting With ALPS.Frontiers in immunologyPubMed ↗
- 2020A Novel Pathogenic Variant in CARMIL2 (RLTPR) Causing CARMIL2 Deficiency and EBV-Associated Smooth Muscle Tumors.Frontiers in immunologyPubMed ↗
- 2015Regulatory T-cell deficiency and immune dysregulation, polyendocrinopathy, enteropathy, X-linked-like disorder caused by loss-of-function mutations in LRBA.The Journal of allergy and clinical immunologyPubMed ↗