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Gene profile

HDAC2

HGNC:4853 · SaudiVarKB evidence summary derived from retained literature mentions.

8Gene mentions
8Publications
0Linked variants
6Associated phenotypes

Associated phenotypes

Co-mentioned in HDAC2 publications
PhenotypeIdentifierArticlesMentions
diabetes mellitus22
asthma22
cardiomyopathyHP:000163811
Alzheimer disease11
autism spectrum disorderHP:000072911
dyslipidemia11

Linked variants

Variants normalized to HDAC2
VariantHGVS / rsIDArticlesMentions

No normalized variants are linked to this gene.

Population context

Reported in the same publications
Country / regionGroupCohortArticles
Not specified601

Supporting publications

8 records
  1. 2026Computational approaches for the identification of potential HDAC2 inhibitors and histamine H3 receptor antagonists from Berberis vulgaris: a dual mechanistic approach for autism spectrum disorder treatment.Open life sciencesPubMed ↗
  2. 2026Interleukin-35 as a key immunoregulatory mediator in steroid-hyporesponsive severe asthma.Frontiers in immunologyPubMed ↗
  3. 2023Bruton's tyrosine kinase inhibition suppresses neutrophilic inflammation and restores histone deacetylase 2 expression in myeloid and structural cells in a mixed granulocytic mouse model of asthma.International immunopharmacologyPubMed ↗
  4. 2023Analysis of global DNA methylation and epigenetic modifiers (DNMTs and HDACs) in human foetal endothelium exposed to gestational and type 2 diabetes.EpigeneticsPubMed ↗
  5. 2023Paget's disease: a review of the epidemiology, etiology, genetics, and treatment.Frontiers in geneticsPubMed ↗
  6. 2020Gene Expression Profiling of Multiple Histone Deacetylases (HDAC) and Its Correlation with NRF2-Mediated Redox Regulation in the Pathogenesis of Diabetic Foot Ulcers.BiomoleculesPubMed ↗
  7. 2011Sex-dimorphism in cardiac nutrigenomics: effect of trans fat and/or monosodium glutamate consumption.BMC genomicsPubMed ↗
  8. 2009Left ventricular global transcriptional profiling in human end-stage dilated cardiomyopathy.GenomicsPubMed ↗