pre-eclampsia
SaudiVarKB evidence summary derived from retained literature mentions.
69Phenotype mentions
69Publications
50Associated gene records
19Associated variant records
Associated gene records
Co-mentioned in the same publications| Gene | Identifier / context | Articles | Mentions |
|---|---|---|---|
| NLRP3 | HGNC:16400 | 2 | 2 |
| G6PD | HGNC:4057 | 2 | 2 |
| MTHFR | HGNC:7436 | 2 | 2 |
| ACE | HGNC:2707 | 2 | 2 |
| FOXP3 | HGNC:6106 | 1 | 1 |
| STAT6 | HGNC:11368 | 1 | 1 |
| LPL | HGNC:6677 | 1 | 1 |
| CD40 | HGNC:11919 | 1 | 1 |
| STAT3 | HGNC:11364 | 1 | 1 |
| MPO | HGNC:7218 | 1 | 1 |
| PTEN | HGNC:9588 | 1 | 1 |
| HMOX1 | HGNC:5013 | 1 | 1 |
| IL10 | HGNC:5962 | 1 | 1 |
| AGL | HGNC:321 | 1 | 1 |
| ABCB1 | HGNC:40 | 1 | 1 |
| EPHX1 | HGNC:3401 | 1 | 1 |
| PTGS2 | HGNC:9605 | 1 | 1 |
| LDLR | HGNC:6547 | 1 | 1 |
| BRAF | HGNC:1097 | 1 | 1 |
| ASPM | HGNC:19048 | 1 | 1 |
| ATP8B1 | HGNC:3706 | 1 | 1 |
| EGFR | HGNC:3236 | 1 | 1 |
| CGA | HGNC:1885 | 1 | 1 |
| ESR1 | HGNC:3467 | 1 | 1 |
| TLR4 | HGNC:11850 | 1 | 1 |
| PAPPA2 | HGNC:14615 | 1 | 1 |
| F5 | HGNC:3542 | 1 | 1 |
| CD44 | HGNC:1681 | 1 | 1 |
| SLC3A1 | HGNC:11025 | 1 | 1 |
| HTRA1 | HGNC:9476 | 1 | 1 |
| FLT1 | HGNC:3763 | 1 | 1 |
| ENG | HGNC:3349 | 1 | 1 |
| FTO | HGNC:24678 | 1 | 1 |
| ZFP36 | HGNC:12862 | 1 | 1 |
| KIF2A | HGNC:6318 | 1 | 1 |
| RPL27A | HGNC:10329 | 1 | 1 |
| CD200R1 | HGNC:24235 | 1 | 1 |
| STAMBP | HGNC:16950 | 1 | 1 |
| CD226 | HGNC:16961 | 1 | 1 |
| IDH1 | HGNC:5382 | 1 | 1 |
| IDH2 | HGNC:5383 | 1 | 1 |
| OGT | HGNC:8127 | 1 | 1 |
| TMEM70 | HGNC:26050 | 1 | 1 |
| P4HA1 | HGNC:8546 | 1 | 1 |
| CYBB | HGNC:2578 | 1 | 1 |
| LEP | HGNC:6553 | 1 | 1 |
| NEAT1 | HGNC:30815 | 1 | 1 |
| SPP1 | HGNC:11255 | 1 | 1 |
| TERT | HGNC:11730 | 1 | 1 |
| GAPDH | HGNC:4141 | 1 | 1 |
Associated variant records
Co-mentioned in the same publications| Variant | Identifier / context | Articles | Mentions |
|---|---|---|---|
| G20210A | G20210A | 2 | 2 |
| rs2232365 | rs2232365 | 1 | 1 |
| p.W577C | p.W577C | 1 | 1 |
| G894T | G894T | 1 | 1 |
| T174M | T174M | 1 | 1 |
| M235T | M235T | 1 | 1 |
| rs1051740 | rs1051740 | 1 | 1 |
| rs2234922 | rs2234922 | 1 | 1 |
| rs268 | rs268 | 1 | 1 |
| rs6025 | rs6025 | 1 | 1 |
| c.668A>G | c.668A>G | 1 | 1 |
| c.1968G>C | c.1968G>C | 1 | 1 |
| rs1137101 | rs1137101 | 1 | 1 |
| rs1805094 | rs1805094 | 1 | 1 |
| 668A>G | 668A>G | 1 | 1 |
| 1968G>C | 1968G>C | 1 | 1 |
| rs10936599 | rs10936599 | 1 | 1 |
| rs2736100 | rs2736100 | 1 | 1 |
| rs12597511 | rs12597511 | 1 | 1 |
Associated population records
Co-mentioned in the same publications| Population | Identifier / context | Articles | Mentions |
|---|---|---|---|
| Saudi Arabia | — | 2 | 2 |
| Population record | Cohort 20 | 1 | 1 |
| Population record | Cohort 1 | 1 | 1 |
| Saudi Arabia · Riyadh | — | 1 | 1 |
| Population record | Cohort 75 | 1 | 1 |
| Population record | Cohort 82 | 1 | 1 |
| Saudi Arabia · Jeddah | — | 1 | 1 |
| Saudi Arabia | Cohort 3 | 1 | 1 |
| Population record | Cohort 200 | 1 | 1 |
| Population record | Cohort 62 | 1 | 1 |
| Population record | Cohort 149 | 1 | 1 |
| Saudi Arabia · Asir | — | 1 | 1 |
| Population record | Cohort 351 | 1 | 1 |
| Saudi Arabia · Riyadh | Cohort 392 | 1 | 1 |
| Population record | Cohort 202 | 1 | 1 |
| Population record | Cohort 225 | 1 | 1 |
| Saudi Arabia · Jeddah | Cohort 94 | 1 | 1 |
| Population record | Cohort 369 | 1 | 1 |
| Saudi Arabia · Riyadh | Cohort 44 | 1 | 1 |
| Population record | Cohort 1,988 | 1 | 1 |
| Saudi Arabia · Riyadh | Cohort 55 | 1 | 1 |
| Population record | Cohort 3,821 | 1 | 1 |
Supporting publications
69 records- 2026Anesthetic management of a cesarean section in a pregnant patient with congenital complete atrioventricular block without pacemaker - A case report.Saudi journal of anaesthesia1 mentions
- 2026Systems-level actions of luteolin in female reproductive disorders: from molecular mechanisms to clinical translation.Frontiers in pharmacology1 mentions
- 2026Placental dysfunction, inflammation, and impaired autophagy in preeclampsia: A pathophysiological link to autism spectrum disorder.Metabolic brain disease1 mentions
- 2026The Role of Maternal Homocysteine Concentration in Pregnancy Complications: A Systematic Review and Meta-Analysis.Journal of clinical medicine1 mentions
- 2026Systemic lupus erythematosus in pregnancy: Maternal and fetal outcomes and management strategies (Review).Medicine international1 mentions
- 2026Oxidative dyslipidemia in early pregnancy: integrating atherogenic index of plasma (AIP) and uric acid (UA) to refine preeclampsia risk stratification.Frontiers in pharmacology1 mentions
- 2026NLRs and preeclampsia: Advances in etiology, pathogenesis, and therapeutic targeting, highlighting NLRP3.Reproductive biology1 mentions
- 2026The endothelin-1/TLR4/NF-κB/NLRP3 inflammasome axis in preeclampsia: a review of a pathological feed-forward loop and therapeutic frontier.Naunyn-Schmiedeberg's archives of pharmacology1 mentions
- 2025Insights on obstetric outcomes in pregnant individuals with Marfan Syndrome: evidence from the National Inpatient Sample.Minerva obstetrics and gynecology1 mentions
- 2025Biochemical investigation of FOXP3 genetic polymorphism and its association with biochemical parameters in pre-eclampsia patients.Naunyn-Schmiedeberg's archives of pharmacology1 mentions
- 2025Maternal epilepsy and pregnancy, delivery and neonatal outcomes: A population-based retrospective cohort study.Epilepsy & behavior : E&B1 mentions
- 2025Exploring gene expression signatures in preeclampsia and identifying hub genes through bioinformatic analysis.Placenta1 mentions
- 2025Pregnancy, delivery, and neonatal outcomes among women with beta-thalassemia major: a population-based study of a large US database.Archives of gynecology and obstetrics1 mentions
- 2025Prophylactic vs therapeutic blood transfusions impact on pregnant sickle cell patients.Pakistan journal of medical sciences1 mentions
- 2025Pregnancy Outcomes in Women with Low and Ultra-Low Ejection Fraction: A Retrospective Study in a Tertiary Care Center.Journal of clinical medicine1 mentions
- 2025The Role of Exosomal miRNAs in Female Infertility: Therapeutic Potential and Mechanisms of Action.Stem cell reviews and reports1 mentions
- 2025Insights into the role of miR-877 and histidine-rich glycoprotein in preeclampsia.Archives of medical science : AMS1 mentions
- 2025Traditional Versus Contemporary Models for Identifying Causes of Maternal Death: A Population-Based Study.BJOG : an international journal of obstetrics and gynaecology1 mentions
- 2025Generalized and focal epilepsy and pregnancy, delivery and neonatal outcomes: a retrospective cohort study.Epilepsy & behavior : E&B1 mentions
- 2025Effectiveness of antihypertensive therapies and maternal-neonatal outcomes in preeclampsia and eclampsia women: an analytical retrospective study from sudan.Journal of family medicine and primary care1 mentions
- 2025Maternal, delivery and neonatal outcomes in women with peripartum cardiomyopathy. A study of a population database.Acta cardiologica1 mentions
- 2025Preeclampsia in Saudi Arabia: A Systematic Review and Meta-Analysis of Prevalence, Risk Factors, Awareness, and Outcomes.Cureus1 mentions
- 2024Identification of polymorphic alleles in TERC and TERT gene reprogramming the telomeres of newborn and legacy with parental health.Saudi journal of biological sciences1 mentions
- 2024Association of ACE*(Insertion/Deletion) Variant with the Elevated Risk of Preeclampsia Among Gestational Women.Biochemical genetics1 mentions
- 2024A complex case of posterior reversible encephalopathy syndrome after combined spinal epidural of preeclampsia parturient: A case report.Saudi journal of anaesthesia1 mentions
- 2024Maternal mortality in the United States: are the high and rising rates due to changes in obstetrical factors, maternal medical conditions, or maternal mortality surveillance?American journal of obstetrics and gynecology1 mentions
- 2024Analyzing molecular signatures in preeclampsia and fetal growth restriction: Identifying key genes, pathways, and therapeutic targets for preterm birth.Frontiers in molecular biosciences1 mentions
- 2024A comparison of obstetric and neonatal outcomes in polycystic ovary syndrome and congenital adrenal hyperplasia: a retrospective analysis of a population database.F&S science1 mentions
- 2024Editorial: The repercussions of maternal inflammation in pre-eclampsia on fetal health and neurodevelopment.Frontiers in immunology1 mentions
- 2024Serum lncRNAs TUG1, H19, and NEAT1 and their target miR-29b/SLC3A1 axis as possible biomarkers of preeclampsia: Potential clinical insights.Non-coding RNA research1 mentions
- 2024Comparative Analysis of Antihypertensive and Anticonvulsant Regimens in Managing Pre-eclampsia and Eclampsia: Insights from a Sudanese Retrospective Study.Medical science monitor : international medical journal of experimental and clinical research1 mentions
- 2023Functions of LncRNAs, exosomes derived MSCs and immune regulatory molecules in preeclampsia disease.Pathology, research and practice1 mentions
- 2023Pregnancy and Inflammatory Rheumatological Diseases: A Single-Center Retrospective Cohort Study.Cureus1 mentions
- 2023The outcome of heart failure in women: a study from a tertiary heart function clinic.American journal of cardiovascular disease1 mentions
- 2022Pregnancy, delivery, and neonatal outcomes among women with psoriatic arthritis, a population based study.Journal of perinatal medicine1 mentions
- 2022Serum biomarkers for the prediction and diagnosis of preeclampsia: A meta-analysis.Journal of Taibah University Medical Sciences1 mentions
- 2022Reduced Abundance of Nitrate-Reducing Bacteria in the Oral Microbiota of Women with Future Preeclampsia.Nutrients1 mentions
- 2022Patterns of antiseizure medication prescription in pregnancy and maternal complications in women with epilepsy: A retrospective study in Saudi Arabia.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society1 mentions
- 2022Interplay between HTRA1 and classical signalling pathways in organogenesis and diseases.Saudi journal of biological sciences1 mentions
- 2022Pre-Existing Diabetes Mellitus, Hypertension and KidneyDisease as Risk Factors of Pre-Eclampsia: A Disease of Theories and Its Association with Genetic Polymorphism.International journal of environmental research and public health1 mentions
- 2022Genetic Polymorphism in Angiotensinogen and Its Association with Cardiometabolic Diseases.Metabolites1 mentions
- 2021MZe786, a hydrogen sulfide-releasing aspirin prevents preeclampsia in heme oxygenase-1 haplodeficient pregnancy under high soluble flt-1 environment.Redox biology1 mentions
- 2021Pregnant women who develop preeclampsia have lower abundance of the butyrate-producer Coprococcus in their gut microbiota.Pregnancy hypertension1 mentions
- 2021Identification and validation of DNA methylation changes in pre-eclampsia.Placenta1 mentions
- 2021Association of endothelial nitric oxide synthase gene variants with preeclampsia.Reproductive health1 mentions
- 2021Reversible Cerebral Vasoconstriction Syndrome in a Background of Eclampsia Responding to Milrinone Infusion.The American journal of case reports1 mentions
- 2020Evaluation of Factor V Leiden and prothrombin G20210A mutations in Sudanese women with severe preeclampsia.Current research in translational medicine1 mentions
- 2020HMOX1 is partly responsible for phenotypic and functional abnormalities in mesenchymal stem cells/stromal cells from placenta of preeclampsia (PE) patients.Stem cell research & therapy1 mentions
- 2020Assessment of insertion/deletion polymorphism of ACE gene as a genetic risk marker for preeclampsia in pregnant women.JPMA. The Journal of the Pakistan Medical Association1 mentions
- 2020Leptin receptor gene polymorphisms c.668A>G and c.1968G>C in Sudanese women with preeclampsia: a case-control study.BMC medical genetics1 mentions
- 2020The association of the prothrombin G20210A single-nucleotide polymorphism and the risk of preeclampsia: Systematic review and meta-analysis.European journal of obstetrics, gynecology, and reproductive biology1 mentions
- 2020Association of Four Missense SNPs with Preeclampsia in Saudi Women.Saudi journal of medicine & medical sciences1 mentions
- 2020Association between preeclampsia and prostasin polymorphism in Pakistani females.Saudi medical journal1 mentions
- 2020Pregnancy-associated hemolytic uremic syndrome.Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia1 mentions
- 2018Deconvoluting the Biological Roles of Vitamin D-Binding Protein During Pregnancy: A Both Clinical and Theoretical Challenge.Frontiers in endocrinology1 mentions
- 2017Myasthenia gravis and preeclampsia: Dot all the I's and cross all the T's.Journal of Taibah University Medical Sciences1 mentions
- 2016Posterior reversible encephalopathy syndrome in a hypertensive patient with renal failure.Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia1 mentions
- 2016Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015) : Jeddah, Kingdom of Saudi Arabia. 30 November - 3 December 2015.BMC genomics1 mentions
- 2015Estrogen Receptor Alpha (ESR1) Gene Polymorphisms in Pre-eclamptic Saudi Patients.Pakistan journal of medical sciences1 mentions
- 2013The eye and visual system in the preeclampsia/eclampsia syndrome: What to expect?Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society1 mentions
- 2013Cardiorespiratory crisis at the end of pregnancy: a case of pheochromocytoma.Middle East journal of anaesthesiology1 mentions
- 2012Morbidity and pregnancy outcomes associated with sickle cell anemia among Saudi women.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics1 mentions
- 2008Peripartum neurological emergencies in a Critical Care Unit.Neurosciences (Riyadh, Saudi Arabia)1 mentions
- 2006Sickle cell disease and pregnancy in Bahrain.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics1 mentions
- 2006The relationship between thrombophilic mutations and preeclampsia: a prospective case-control study.Annals of Saudi medicine1 mentions
- 2006The relationship between pregnancy induced hypertension and congenital thrombophilia.Saudi medical journal1 mentions
- 2005Hyperhomocysteinemia in pregnant rats: effects on arterial pressure, kidneys and fetal growth.European journal of obstetrics, gynecology, and reproductive biology1 mentions
- 2004Glucose 6 phosphate dehydrogenase (G6PD) deficiency is a possible risk factor for the development of preeclampsia.Medical hypotheses1 mentions
- 2002Severe preeclampsia and the very-low-birth-weight infant. The controversy over delivery mode continues.The Journal of reproductive medicine1 mentions