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Gene profile

CYP2C8

HGNC:2622 · SaudiVarKB evidence summary derived from retained literature mentions.

6Gene mentions
6Publications
4Linked variants
2Associated phenotypes

Associated phenotypes

Co-mentioned in CYP2C8 publications
PhenotypeIdentifierArticlesMentions
diabetes mellitus11
rheumatoid arthritis11

Linked variants

Variants normalized to CYP2C8
VariantHGVS / rsIDArticlesMentions
I269F11
R139K11
C144R11
L359A11

Population context

Reported in the same publications
Country / regionGroupCohortArticles
Saudi Arabia1
Saudi Arabia1401
Saudi Arabia7861
Not specified2181

Supporting publications

6 records
  1. 2026USFDA-Approved Small Molecules in the Year 2025: Medicinal Chemistry Strategies and Trends.Archiv der PharmaziePubMed ↗
  2. 2024Pediatric pharmacogenetics: profiling CYP2C8 polymorphisms at King Abdulaziz University Dental Clinic.Drug metabolism and personalized therapyPubMed ↗
  3. 2023Targeted next-generation sequencing of genes involved in Warfarin Pharmacodynamics and pharmacokinetics pathways using the Saudi Warfarin Pharmacogenetic study (SWAP).The pharmacogenomics journalPubMed ↗
  4. 2023Association of CYP2C9∗3 and CYP2C8∗3 Non-Functional Alleles with Ibuprofen-Induced Upper Gastrointestinal Toxicity in a Saudi Patient.Case reports in medicinePubMed ↗
  5. 2021Utilizing Large Electronic Medical Record Data Sets to Identify Novel Drug-Gene Interactions for Commonly Used Drugs.Clinical pharmacology and therapeuticsPubMed ↗
  6. 2017Distribution of CYP2C8 and CYP2C9 amino acid substitution alleles in South Indian diabetes patients: A genotypic and computational protein phenotype study.Clinical and experimental pharmacology & physiologyPubMed ↗