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Gene profile

SOX2

HGNC:11195 · SaudiVarKB evidence summary derived from retained literature mentions.

18Gene mentions
18Publications
2Linked variants
6Associated phenotypes

Associated phenotypes

Co-mentioned in SOX2 publications
PhenotypeIdentifierArticlesMentions
breast cancer22
leukemia11
diabetes mellitus11
thyroid cancer11
colorectal cancer11
lung cancer11

Linked variants

Variants normalized to SOX2
VariantHGVS / rsIDArticlesMentions
rs4434184rs443418411
rs881301rs88130111

Population context

Reported in the same publications
Country / regionGroupCohortArticles
Not specified601
Not specified371

Supporting publications

18 records
  1. 2026Cardiac drug potential: exploring individual and combined cardiac drugs to promote differentiation of adipose-derived stem cells into cardiomyocytes.Molecular biology reportsPubMed ↗
  2. 2026Integrated biomarker mapping reveals differential expression of senescence profiles in IDH-wild-type glioblastoma recurrent versus primary tumors.Virchows Archiv : an international journal of pathologyPubMed ↗
  3. 2026Squamous Cancers and Precancers of the Vulva: Emerging Diagnostic, Prognostic and Predictive Biomarkers in Pathology.CancersPubMed ↗
  4. 2026Transcription Factors in the Pathogenesis of Schizophrenia.Life (Basel, Switzerland)PubMed ↗
  5. 2026Exploring hypoxia-related genes as prognostic indicators in lung adenocarcinoma.PloS onePubMed ↗
  6. 2025A cutting-edge investigation of the multifaceted role of SOX family genes in cancer pathogenesis through the modulation of various signaling pathways.Functional & integrative genomicsPubMed ↗
  7. 2025Distinct Phenotypic and Molecular Characteristics of CD34- and CD34+ Hematopoietic Stem/Progenitor Cell Subsets in Cord Blood and Bone Marrow Samples: Implications for Clinical Applications.Diagnostics (Basel, Switzerland)PubMed ↗
  8. 2025Polymorphisms in SOX2/FGFR1 are associated with skeletal class III maxillary and mandibular dimensions: A preliminary study.Journal of Taibah University Medical SciencesPubMed ↗
  9. 2025Optimizing extended embryo culture and trophoblast derivation in sheep.TheriogenologyPubMed ↗
  10. 2025RNA Expression Signatures in Glioblastoma: A Systematic Review of Tumour Biology and Therapeutic Targets.Oncology researchPubMed ↗
  11. 2025Interplay between Epigenetic and Transcription Factors Mediating Drug Resistance via Stem Cells in Breast Cancer.ACS omegaPubMed ↗
  12. 2022Meta-analysis of whole-genome gene expression datasets assessing the effects of IDH1 and IDH2 mutations in isogenic disease models.Scientific reportsPubMed ↗
  13. 2021Long intergenic non-coding RNA, regulator of reprogramming (LINC-ROR) over-expression predicts poor prognosis in renal cell carcinoma.Archives of medical science : AMSPubMed ↗
  14. 2021Recurrence biomarkers of triple negative breast cancer treated with neoadjuvant chemotherapy and anti-EGFR antibodies.NPJ breast cancerPubMed ↗
  15. 2020Metformin treatment decreases the expression of cancer stem cell marker CD44 and stemness related gene expression in primary oral cancer cells.Archives of oral biologyPubMed ↗
  16. 2020Switches of SOX17 and SOX2 expression in the development of squamous metaplasia and squamous intraepithelial lesions of the uterine cervix.Cancer medicinePubMed ↗
  17. 2018Current and emerging biomarkers in tumors of the central nervous system: Possible diagnostic, prognostic and therapeutic applications.Seminars in cancer biologyPubMed ↗
  18. 2017MicroRNA-34a: A Key Regulator in the Hallmarks of Renal Cell Carcinoma.Oxidative medicine and cellular longevityPubMed ↗