NPM1
HGNC:7910 · SaudiVarKB evidence summary derived from retained literature mentions.
15Gene mentions
15Publications
1Linked variants
3Associated phenotypes
Associated phenotypes
Co-mentioned in NPM1 publications| Phenotype | Identifier | Articles | Mentions |
|---|---|---|---|
| leukemia | — | 13 | 13 |
| lymphoma | — | 1 | 1 |
| Noonan syndrome | — | 1 | 1 |
Linked variants
Variants normalized to NPM1| Variant | HGVS / rsID | Articles | Mentions |
|---|---|---|---|
| S34F | — | 1 | 1 |
Population context
Reported in the same publications| Country / region | Group | Cohort | Articles |
|---|---|---|---|
| Saudi Arabia · Jeddah | — | 87 | 1 |
| Not specified | — | 30 | 1 |
| Not specified | — | 15 | 1 |
| Not specified | — | 35 | 1 |
| Not specified | — | 131 | 1 |
| Not specified | — | 78 | 1 |
| Not specified | — | 1,888 | 1 |
| Not specified | — | 600 | 1 |
Supporting publications
15 records- 2026The impact of DNMT3A mutation on survival of AML patients receiving allotransplant in first remission depends on the karyotype and co-occurring mutations.Bone marrow transplantation1 mentions
- 2026Targeting the Menin-KMT2A Interface: Medicinal Chemistry Rules Governing Reversible, Covalent, and Degrader Inhibitors.Chemical biology & drug design1 mentions
- 2026Epigenetics and In Silico Transcriptome Analysis of Pediatric Acute Myeloid Leukemia.European journal of haematology1 mentions
- 2025Molecular Analysis of Genes CEBPA, NPM1, IDH1, and RUNX1 Polymorphisms as Biomarker Potential in Leukemia Patients.Molecular carcinogenesis1 mentions
- 2025HOX-PBX Up-regulation Predicts Favorable Prognosis in NPM1-mutated Normal Cytogenetic AML via WNT Signaling.Anticancer research1 mentions
- 2024Application of Newly Customized Myeloid NGS Panel in the Diagnosis of Myeloid Malignancies.International journal of general medicine1 mentions
- 2024An Ultra-Fast Validated Green UPLC-MS/MS Approach for Assessing Revumenib in Human Liver Microsomes: In Vitro Absorption, Distribution, Metabolism, and Excretion and Metabolic Stability Evaluation.Medicina (Kaunas, Lithuania)1 mentions
- 2022Decreased CD177pos neutrophils in myeloid neoplasms is associated with NPM1, RUNX1, TET2, and U2AF1 S34F mutations.Leukemia research1 mentions
- 2021Prognostic relevance of combined IDH1 and NPM1 mutations in the intermediate cytogenetic de novo acute myeloid leukemia.Cellular and molecular biology (Noisy-le-Grand, France)1 mentions
- 2020Comprehensive Genomic Analysis of Noonan Syndrome and Acute Myeloid Leukemia in Adults: A Review and Future Directions.Acta haematologica1 mentions
- 2019Overall survival of adult acute myeloid leukemia based on cytogenetic and molecular abnormalities during 5 years in a single center study.Saudi medical journal1 mentions
- 2013A surrogate marker to detect nucleophosnim (NPM1) gene mutations in the cytoplasm of acute myeloid leukemia (AML) blast cells in 30 adult Iraqi patients.Annals of Saudi medicine1 mentions
- 2013Novel t(7;10)(p22;p24) along with NPM1 mutation in patient with relapsed acute myeloid leukemia.Annals of Saudi medicine1 mentions
- 2011Detection of nucleophosmin and FMS-like tyrosine kinase-3 gene mutations in acute myeloid leukemia.Annals of Saudi medicine1 mentions
- 2008The challenge of risk stratification in acute myeloid leukemia with normal karyotype.Hematology/oncology and stem cell therapy1 mentions