E2F1
HGNC:3113 · SaudiVarKB evidence summary derived from retained literature mentions.
12Gene mentions
12Publications
0Linked variants
8Associated phenotypes
Associated phenotypes
Co-mentioned in E2F1 publications| Phenotype | Identifier | Articles | Mentions |
|---|---|---|---|
| breast cancer | — | 5 | 5 |
| leukemia | — | 3 | 3 |
| epilepsy | HP:0001250 | 1 | 1 |
| thyroid cancer | — | 1 | 1 |
| renal failure | — | 1 | 1 |
| hepatocellular carcinoma | — | 1 | 1 |
| COVID-19 | — | 1 | 1 |
| stroke | — | 1 | 1 |
Linked variants
Variants normalized to E2F1| Variant | HGVS / rsID | Articles | Mentions |
|---|
No normalized variants are linked to this gene.
Population context
Reported in the same publications| Country / region | Group | Cohort | Articles |
|---|---|---|---|
| Not specified | — | 19 | 1 |
| Not specified | — | 106 | 1 |
Supporting publications
12 records- 2026Differential Expression and Target Gene Analysis of PBMC-Derived microRNAs as Prognostic Biomarkers in Acute Lymphoblastic Leukemia.International journal of molecular sciencesPubMed ↗
- 2025E2F1 activates breast stromal fibroblasts and promotes their paracrine pro-carcinogenic effects.Scientific reportsPubMed ↗
- 2024Novel 2 Gene Signatures Associated With Breast Cancer Proliferation: Insights From Predictive Differential Gene Expression Analysis.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, IncPubMed ↗
- 2024Analysis of E2F1 single-nucleotide polymorphisms reveals deleterious non-synonymous substitutions that disrupt E2F1-RB protein interaction in cancer.International journal of biological macromoleculesPubMed ↗
- 2024An Integrated Framework to Identify Prognostic Biomarkers and Novel Therapeutic Targets in Hepatocellular Carcinoma-Based Disabilities.BiologyPubMed ↗
- 2023A new machine learning based computational framework identifies therapeutic targets and unveils influential genes in pancreatic islet cells.GenePubMed ↗
- 2023Food Toxicity of Mycotoxin Citrinin and Molecular Mechanisms of Its Potential Toxicity Effects through the Implicated Targets Predicted by Computer-Aided Multidimensional Data Analysis.Life (Basel, Switzerland)PubMed ↗
- 2021An Agathokakological Tale of Δ9-THC: Exploration of Possible Biological Targets.Current drug targetsPubMed ↗
- 2021Gene Expression Analysis of Pediatric Acute Myeloid Leukemia Identified a Hyperactive ASXL1/BAP1 Axis Linked with Poor Prognosis and over Expressed Epigenetic Modifiers.Pediatric hematology and oncologyPubMed ↗
- 2021Network-based transcriptomic analysis identifies the genetic effect of COVID-19 to chronic kidney disease patients: A bioinformatics approach.Saudi journal of biological sciencesPubMed ↗
- 2021Mutational Landscape of Pirin and Elucidation of the Impact of Most Detrimental Missense Variants That Accelerate the Breast Cancer Pathways: A Computational Modelling Study.Frontiers in molecular biosciencesPubMed ↗
- 2017Comprehensive molecular biomarker identification in breast cancer brain metastases.Journal of translational medicinePubMed ↗