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Gene profile

TLR8

HGNC:15632 · SaudiVarKB evidence summary derived from retained literature mentions.

11Gene mentions
11Publications
2Linked variants
5Associated phenotypes

Associated phenotypes

Co-mentioned in TLR8 publications
PhenotypeIdentifierArticlesMentions
SARS22
COVID-1911
tuberculosis11
hepatitis C11
hepatitis B11

Linked variants

Variants normalized to TLR8
VariantHGVS / rsIDArticlesMentions
rs5744080rs574408011
rs2159377rs215937711

Population context

Reported in the same publications
Country / regionGroupCohortArticles
Saudi Arabia451
Not specified3,3681
Not specified4341

Supporting publications

11 records
  1. 2026TZ1391: a computationally designed circular mRNA multi-epitope vaccine candidate against Mycobacterium tuberculosis via TLR3 immunomodulation.BMC immunology1 mentions
  2. 20262'-O-Methyl-guanosine RNA fragments antagonize TLR7 and TLR8 to limit autoimmunity.Nature immunology1 mentions
  3. 2026Integrated Computational and In Vivo Assessment of a Novel Multi-Epitope Vaccine Against Dengue Virus Serotype 4 Capsid Protein.Microbiology and immunology1 mentions
  4. 2026Clinical study and the diagnosis of lumpy skin disease in cattle using genomic, immunological, and pathological indicators.Frontiers in veterinary science1 mentions
  5. 2025Robust Multiepitope Vaccine from Glycoproteins Against Human Metapneumovirus Genotypes A2a, A2b, and A2c by Utilizing Immunoinformatics and Reverse Vaccinology Approaches.Viral immunology1 mentions
  6. 2025Downregulation of Toll-Like Receptor Gene Expression Among Hepatitis B Virus-Positive Human Patients.Cureus1 mentions
  7. 2025Molecular assessment of the HIV pol gene and use of computational vaccine design targeting Pakistani isolates.Scientific reports1 mentions
  8. 2024Exploring advanced genomic and immunoinformatics techniques for identifying drug and vaccine targets against SARS-CoV-2.Journal, genetic engineering & biotechnology1 mentions
  9. 2023Individual Genomic Loci and mRNA Levels of Immune Biomarkers Associated with Pneumonia Susceptibility in Baladi Goats.Veterinary sciences1 mentions
  10. 2021TLR8 is highly conserved among the Saudi population and its mutations have no effect on the severity of COVID-19 symptoms.American journal of clinical and experimental immunology1 mentions
  11. 2018The association of single nucleotide polymorphisms of Toll-like receptor 3, Toll-like receptor 7 and Toll-like receptor 8 genes with the susceptibility to HCV infection.British journal of biomedical science1 mentions