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Variant profile

rs1801133

rs1801133 · SaudiVarKB evidence summary derived from retained literature mentions.

10Variant mentions
10Publications
16Associated gene records
11Associated phenotype records

Associated gene records

Co-mentioned in the same publications
GeneIdentifier / contextArticlesMentions
MTHFRHGNC:74361010
OR51V1HGNC:1959711
OR52A5HGNC:1958011
OR51B5HGNC:1959911
CBSHGNC:155011
TP53HGNC:1199811
ABCC2HGNC:5311
ACEHGNC:270711
OR51A1PHGNC:831611
OR51E2HGNC:1519511
OR52K1HGNC:1522211
OR52K2HGNC:1522311
OR52T1PHGNC:1523611
OLFM5PHGNC:5192711
PON1HGNC:920411
MTRHGNC:746811

Associated phenotype records

Co-mentioned in the same publications
PhenotypeIdentifier / contextArticlesMentions
epilepsyHP:000125033
diabetes mellitus22
autism spectrum disorderHP:000072922
stroke22
myocardial infarction22
intellectual disabilityHP:000124911
developmental delayHP:000126311
sickle cell diseaseHP:0001878 · 60390311
coronary artery disease11
breast cancer11
recurrent pregnancy loss11

Associated population records

Co-mentioned in the same publications
PopulationIdentifier / contextArticlesMentions
Saudi Arabia11
Population recordCohort 211
Population recordCohort 2,43111
Saudi ArabiaCohort 11211
Population recordCohort 50411
Population recordCohort 30011
Population recordCohort 24211
Population recordCohort 29611
Saudi Arabia · JeddahCohort 10111

Supporting publications

10 records
  1. 2025High penetrance and phenotypic landscape of methylenetetrahydrofolate reductase c.665 C>T polymorphism in the absence of folate fortification.Clinical nutrition ESPEN1 mentions
  2. 2025Genetic variants and breast carcinoma susceptibility: Unveiling the role of MTHFR (rs1801131, rs1801133) and TP53 (rs1042522).Gene1 mentions
  3. 2025Colorimetric loop-mediated isothermal amplification (cLAMP) assay for the genotyping of a thrombophilia genetic risk factor, MTHFR (C677T).Analytical methods : advancing methods and applications1 mentions
  4. 2023Biochemical Association of MTHFR C677T Polymorphism with Myocardial Infarction in the Presence of Diabetes Mellitus as a Risk Factor.Metabolites1 mentions
  5. 2023Impact of Genetic Variations on Thromboembolic Risk in Saudis with Sickle Cell Disease.Genes1 mentions
  6. 2022Role of metabolizing MTHFR gene polymorphism (rs1801133) and its mRNA expression among Type 2 Diabetes.Journal of diabetes and metabolic disorders1 mentions
  7. 2022Association of Polymorphism of the Methyl Tetrahydrofolate Reductase (MTHFR) Gene with Anti-Seizure Medication Response in Pediatric Patients in Jeddah, Saudi Arabia.Medicina (Kaunas, Lithuania)1 mentions
  8. 2019Effects of MTHFR and ABCC2 gene polymorphisms on antiepileptic drug responsiveness in Jordanian epileptic patients.Pharmacogenomics and personalized medicine1 mentions
  9. 2019Methylenetetrahydrofolate Reductase Gene Variants Confer Potential Vulnerability to Autism Spectrum Disorder in a Saudi Community.Neuropsychiatric disease and treatment1 mentions
  10. 2017The communal relation of MTHFR, MTR, ACE gene polymorphisms and hyperhomocysteinemia as conceivable risk of coronary artery disease.Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme1 mentions