ULK1
HGNC:12558 · SaudiVarKB evidence summary derived from retained literature mentions.
9Gene mentions
9Publications
0Linked variants
6Associated phenotypes
Associated phenotypes
Co-mentioned in ULK1 publications| Phenotype | Identifier | Articles | Mentions |
|---|---|---|---|
| intellectual disability | HP:0001249 | 2 | 2 |
| cardiomyopathy | HP:0001638 | 1 | 1 |
| Parkinson disease | — | 1 | 1 |
| developmental delay | HP:0001263 | 1 | 1 |
| Noonan syndrome | — | 1 | 1 |
| Crohn disease | — | 1 | 1 |
Linked variants
Variants normalized to ULK1| Variant | HGVS / rsID | Articles | Mentions |
|---|
No normalized variants are linked to this gene.
Population context
Reported in the same publications| Country / region | Group | Cohort | Articles |
|---|---|---|---|
| Not specified | — | — | 1 |
| Not specified | — | 100 | 1 |
Supporting publications
9 records- 2026Resveratrol alleviates neurological disorders and motor dysfunction in 3-NP induced- Huntington's Disease in rats: Role of activating AMPK/SIRT1/ULK1 autophagy pathway.NeuropharmacologyPubMed ↗
- 2025Cognitive and psychotic effects of ketamine "short- vs. long-term" therapy in a rat model of depression: Hippocampal TrkB/Akt/GSK-3β/mTOR/autophagy trajectories.Progress in neuro-psychopharmacology & biological psychiatryPubMed ↗
- 2024Trigonelline Chloride Ameliorated Triphenyltin-Induced Testicular Autophagy, Inflammation, and Apoptosis: Role of Recovery.Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of CanadaPubMed ↗
- 2024The autophagy-mediated mechanism via TSC1/mTOR signaling pathway in thiram-induced tibial dyschondroplasia of broilers.The Science of the total environmentPubMed ↗
- 2023Bisphenol-A exposure alters liver, kidney, and pancreatic Klotho expression by HSP60-activated mTOR/autophagy pathway in male albino rats.Cellular and molecular biology (Noisy-le-Grand, France)PubMed ↗
- 2021Investigation of the specificity and mechanism of action of the ULK1/AMPK inhibitor SBI-0206965.The Biochemical journalPubMed ↗
- 2020Categorized Genetic Analysis in Childhood-Onset Cardiomyopathy.Circulation. Genomic and precision medicinePubMed ↗
- 2019ULK1-mediated phosphorylation of ATG16L1 promotes xenophagy, but destabilizes the ATG16L1 Crohn's mutant.EMBO reportsPubMed ↗
- 2011Chromosome 12q24.31-q24.33 deletion causes multiple dysmorphic features and developmental delay: First mosaic patient and overview of the phenotype related to 12q24qter defects.Molecular cytogeneticsPubMed ↗