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Gene profile

BCR

HGNC:1014 · SaudiVarKB evidence summary derived from retained literature mentions.

20Gene mentions
20Publications
0Linked variants
10Associated phenotypes

Associated phenotypes

Co-mentioned in BCR publications
PhenotypeIdentifierArticlesMentions
leukemia1616
diabetes mellitus22
hypertension11
lymphoma11
Down syndrome11
von Willebrand disease11
COVID-1911
colorectal cancer11
lung cancer11
MERS11

Linked variants

Variants normalized to BCR
VariantHGVS / rsIDArticlesMentions

No normalized variants are linked to this gene.

Population context

Reported in the same publications
Country / regionGroupCohortArticles
Saudi Arabia1
Not specified1031
Not specified1301
Not specified321
Saudi Arabia161
Saudi Arabia851

Supporting publications

20 records
  1. 2026The emerging role of immunotherapy in improving outcomes in Down syndrome - associated acute lymphoblastic leukemia: an insightful review.Leukemia & lymphomaPubMed ↗
  2. 2026Management of tyrosine kinase inhibitors and donor lymphocyte infusions post transplantation for chronic myeloid leukemia: a survey of contemporary practice on behalf of the chronic malignancies working party of the EBMT.Bone marrow transplantationPubMed ↗
  3. 2026Experimental Validation and Computational Deconstruction of Downstream Mutations in MIR5195: Integrating Whole-Exome Sequencing, Structural Dynamics, and Molecular Docking to Decipher Transcriptional Reprogramming in CML.Cell biochemistry and biophysicsPubMed ↗
  4. 2025An Updated Review of the Anticancer Mechanisms and Therapeutic Potential of Naringenin.Food science & nutritionPubMed ↗
  5. 2025Anticancer Molecular Mechanisms of Epigallocatechin Gallate: An Updated Review on Clinical Trials.Food science & nutritionPubMed ↗
  6. 2024Exploring the interplay between microRNA expression and DNA mutation analysis in AML patients.Saudi journal of biological sciencesPubMed ↗
  7. 2024Chronic Myeloid Leukemia with a Rare Philadelphia Chromosome Variant Involving Chromosome 16.The American journal of case reportsPubMed ↗
  8. 2023A 68-Year-Old Man with a Cytogenetic Diagnosis of Chronic Myeloid Leukemia and Bone Marrow Findings of Philadelphia Chromosome Translocation Between the Long Arm of Chromosomes 9 and 22, Leading to the BCR-ABL1 Fusion Gene and V617F Mutation in the JAK2 Gene.The American journal of case reportsPubMed ↗
  9. 2022Role of Potential COVID-19 Immune System Associated Genes and the Potential Pathways Linkage with Type-2 Diabetes.Combinatorial chemistry & high throughput screeningPubMed ↗
  10. 2022Saudi Arabian CML patient with a novel four-way translocation at t(9;22;5;2)(q34;q11.2;p13;q44).Molecular genetics & genomic medicinePubMed ↗
  11. 2020Ectopic PD-L1 expression in JAK2 (V617F) myeloproliferative neoplasm patients is mediated via increased activation of STAT3 and STAT5.Human cellPubMed ↗
  12. 2018Current paradigms in the management of Philadelphia chromosome positive acute lymphoblastic leukemia in adults.American journal of hematologyPubMed ↗
  13. 2017A rare case of three-way complex variant translocation in chronic myeloid leukemia t(6;9;22)(p21;q34;q11): A case report.Biomedical reportsPubMed ↗
  14. 2016A rare case of a three way complex variant positive Philadelphia translocation involving chromosome (9;11;22)(q34;p15;q11) in chronic myeloid leukemia: A case report.Oncology lettersPubMed ↗
  15. 2015Three-way complex variant translocation involving short arm chromosome (1;9;22)(p36;q34;q11) in a chronic myeloid leukemia patient.Oncology lettersPubMed ↗
  16. 2014A comprehensive analysis of breakpoint cluster region-abelson fusion oncogene splice variants in chronic myeloid leukemia and their correlation with disease biology.Indian journal of human geneticsPubMed ↗
  17. 2010Molecular monitoring of response to imatinib (Glivec) in chronic myeloid leukemia patients: experience at a tertiary care hospital in Saudi Arabia.Genetic testing and molecular biomarkersPubMed ↗
  18. 2008Expression of CD66c and CD25 in acute lymphoblastic leukemia as a predictor of the presence of BCR/ABL rearrangement.Hematology/oncology and stem cell therapyPubMed ↗
  19. 2006Molecular detection of BCR/ABL fusion gene in Saudi acute lymphoblastic leukemia patients.Journal of the Egyptian National Cancer InstitutePubMed ↗
  20. 2005Molecular hematology. Qualitative to quantitative techniques.Saudi medical journalPubMed ↗