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Variant profile

G12C

G12C · SaudiVarKB evidence summary derived from retained literature mentions.

4Variant mentions
4Publications
1Associated gene records
1Associated phenotype records

Associated gene records

Co-mentioned in the same publications
GeneIdentifier / contextArticlesMentions
KRASHGNC:640744

Associated phenotype records

Co-mentioned in the same publications
PhenotypeIdentifier / contextArticlesMentions
lung cancer11

Associated population records

Co-mentioned in the same publications
PopulationIdentifier / contextArticlesMentions
Saudi Arabia11

Supporting publications

4 records
  1. 2025Targeting KRAS-G12C in lung cancer: The emerging role of PROTACs in overcoming resistance.Pathology, research and practice1 mentions
  2. 2024Flavonoids as potential KRAS inhibitors: DFT, molecular docking, molecular dynamics simulation and ADMET analyses.Journal of Asian natural products research1 mentions
  3. 2023Establishing the Role of Iridoids as Potential Kirsten Rat Sarcoma Viral Oncogene Homolog G12C Inhibitors Using Molecular Docking; Molecular Docking Simulation; Molecular Mechanics Poisson-Boltzmann Surface Area; Frontier Molecular Orbital Theory; Molecular Electrostatic Potential; and Absorption, Distribution, Metabolism, Excretion, and Toxicity Analysis.Molecules (Basel, Switzerland)1 mentions
  4. 2022KRAS G12C-Mutant Non-Small-Cell Lung Adenocarcinoma: First Documented Report in the Arabian Gulf.Cureus1 mentions