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Gene profile

TET2

HGNC:25941 · SaudiVarKB evidence summary derived from retained literature mentions.

11Gene mentions
11Publications
0Linked variants
8Associated phenotypes

Associated phenotypes

Co-mentioned in TET2 publications
PhenotypeIdentifierArticlesMentions
leukemia55
epilepsyHP:000125011
rheumatoid arthritis11
developmental delayHP:000126311
neurodevelopmental disorderHP:001275911
asthma11
stroke11
myocardial infarction11

Linked variants

Variants normalized to TET2
VariantHGVS / rsIDArticlesMentions

No normalized variants are linked to this gene.

Population context

Reported in the same publications
Country / regionGroupCohortArticles
Not specified161
Not specified21
Not specified151
Not specified1,5141

Supporting publications

11 records
  1. 2026Epigenetics and In Silico Transcriptome Analysis of Pediatric Acute Myeloid Leukemia.European journal of haematologyPubMed ↗
  2. 2026CHIP In cardiovascular and immune ageing.Ageing research reviewsPubMed ↗
  3. 2025Leukemias in the Context of Rheumatoid Arthritis: Shared Pathways and Clinical Perspectives.CureusPubMed ↗
  4. 2024Application of Newly Customized Myeloid NGS Panel in the Diagnosis of Myeloid Malignancies.International journal of general medicinePubMed ↗
  5. 2022Decreased CD177pos neutrophils in myeloid neoplasms is associated with NPM1, RUNX1, TET2, and U2AF1 S34F mutations.Leukemia researchPubMed ↗
  6. 2022A homozygous frame-shift variant in PROSER1 is associated with developmental delay, hypotonia, genitourinary malformations, and distinctive facial features.Clinical geneticsPubMed ↗
  7. 2021Gene Expression Analysis of Pediatric Acute Myeloid Leukemia Identified a Hyperactive ASXL1/BAP1 Axis Linked with Poor Prognosis and over Expressed Epigenetic Modifiers.Pediatric hematology and oncologyPubMed ↗
  8. 2021Isolated ten-eleven translocation 2 positive in triple negative essential thrombocythemia: Case report and literature review.SAGE open medical case reportsPubMed ↗
  9. 2020A Personalized Prediction Model for Outcomes after Allogeneic Hematopoietic Cell Transplant in Patients with Myelodysplastic Syndromes.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow TransplantationPubMed ↗
  10. 2015Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank.The Lancet. Respiratory medicinePubMed ↗
  11. 2013TET2 mutations, myelodysplastic features, and a distinct immunoprofile characterize blastic plasmacytoid dendritic cell neoplasm in the bone marrow.American journal of hematologyPubMed ↗