PINK1
HGNC:14581 · SaudiVarKB evidence summary derived from retained literature mentions.
14Gene mentions
14Publications
4Linked variants
8Associated phenotypes
Associated phenotypes
Co-mentioned in PINK1 publications| Phenotype | Identifier | Articles | Mentions |
|---|---|---|---|
| Parkinson disease | — | 9 | 9 |
| cardiomyopathy | HP:0001638 | 1 | 1 |
| Alzheimer disease | — | 1 | 1 |
| diabetes mellitus | — | 1 | 1 |
| multiple sclerosis | — | 1 | 1 |
| amyotrophic lateral sclerosis | — | 1 | 1 |
| stroke | — | 1 | 1 |
| breast cancer | — | 1 | 1 |
Linked variants
Variants normalized to PINK1Population context
Reported in the same publications| Country / region | Group | Cohort | Articles |
|---|---|---|---|
| Saudi Arabia | — | 2 | 1 |
| Not specified | — | 1,322 | 1 |
| Saudi Arabia | — | 5 | 1 |
| Not specified | — | 14 | 1 |
Supporting publications
14 records- 2026Cardioprotective effects of 3-N-Butylphthalide in diabetic cardiomyopathy: focus on balanced mitochondrial dynamics and pyroptosis pathways.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of PharmacologyPubMed ↗
- 2026Dose-dependent neurotoxic effects of anastrozole via disrupting NLRP3 inflammasome and α-synuclein pathways.Tissue & cellPubMed ↗
- 2026Loss of PINK1 causes age-dependent mitochondrial trafficking deficits in nigrostriatal dopaminergic neurons via aberrant p38 MAPK activation.NPJ Parkinson's diseasePubMed ↗
- 2025Hyperoside flavonoids protect against malathion-induced mitochondrial toxicity in the differentiated SH-SY5Y cells.Naunyn-Schmiedeberg's archives of pharmacologyPubMed ↗
- 2025Computational association in parkinson's disease SNPs with brain structural and functional alterations.NeurogeneticsPubMed ↗
- 2024Repurposing the inhibitors of MMP-9 and SGLT-2 against ubiquitin specific protease 30 in Parkinson's disease: computational modelling studies.Journal of biomolecular structure & dynamicsPubMed ↗
- 2023Embracing Monogenic Parkinson's Disease: The MJFF Global Genetic PD Cohort.Movement disorders : official journal of the Movement Disorder SocietyPubMed ↗
- 2023Intrafamilial and interfamilial heterogeneity of PINK1-associated Parkinson's disease in Sudan.Parkinsonism & related disordersPubMed ↗
- 2023Gene Signals and SNPs Associated with Parkinson's Disease: A Nutrigenomics and Computational Prospective Insights.NeurosciencePubMed ↗
- 2022The Role of Mitochondrial Genes in Neurodegenerative Disorders.Current neuropharmacologyPubMed ↗
- 2018Mitochondrial dynamics: Biological roles, molecular machinery, and related diseases.Molecular genetics and metabolismPubMed ↗
- 2017Early-Onset Parkinsonism: Case Report and Review of the Literature.Pediatric neurologyPubMed ↗
- 2015Parkinson's Disease in Saudi Patients: A Genetic Study.PloS onePubMed ↗
- 2006T313M PINK1 mutation in an extended highly consanguineous Saudi family with early-onset Parkinson disease.Archives of neurologyPubMed ↗