IRS1
HGNC:6125 · SaudiVarKB evidence summary derived from retained literature mentions.
13Gene mentions
13Publications
1Linked variants
3Associated phenotypes
Associated phenotypes
Co-mentioned in IRS1 publications| Phenotype | Identifier | Articles | Mentions |
|---|---|---|---|
| diabetes mellitus | — | 8 | 8 |
| dyslipidemia | — | 1 | 1 |
| metabolic syndrome | — | 1 | 1 |
Linked variants
Variants normalized to IRS1| Variant | HGVS / rsID | Articles | Mentions |
|---|---|---|---|
| rs1801278 | rs1801278 | 1 | 1 |
Population context
Reported in the same publications| Country / region | Group | Cohort | Articles |
|---|---|---|---|
| Saudi Arabia | — | — | 1 |
| Not specified | — | 20 | 1 |
| Not specified | — | 56 | 1 |
| Not specified | — | 753 | 1 |
| Saudi Arabia | — | 143 | 1 |
| Not specified | — | 614 | 1 |
Supporting publications
13 records- 2025Combined Bioinformatic and Experimental Approaches to Analyze miR-182-3p and miR-24-3p Expression and Their Target Genes in Gestational Diabetes Mellitus and Iron Deficiency Anemia During Pregnancy.Current issues in molecular biologyPubMed ↗
- 2024Viscosol Treatment Ameliorates Insulin-Mediated Regulation of Dyslipidemia, Hepatic Steatosis, and Lipid Metabolism by Targeting PTP1B in Type-2 Diabetic Mice Model.International journal of endocrinologyPubMed ↗
- 2023Abundance of proteins and genes associated with nutrient signaling, protein turnover, and transport of amino acids and glucose in fetuses from lactating Holstein cows.Research in veterinary sciencePubMed ↗
- 2022Hongqu Rice Wines Ameliorate High-Fat/High-Fructose Diet-Induced Metabolic Syndrome in Rats.Alcohol and alcoholism (Oxford, Oxfordshire)PubMed ↗
- 2021Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.Nature communicationsPubMed ↗
- 2021Variations in the insulin receptor substrate 1 (IRS1) and its association with growth traits in Chinese black Tibetan sheep (Ovis aries).Animal biotechnologyPubMed ↗
- 2019Effect of Olea europaea leaves extract on streptozotocin induced diabetes in male albino rats.Saudi journal of biological sciencesPubMed ↗
- 2017Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.Nature communicationsPubMed ↗
- 2016Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci.DiabetesPubMed ↗
- 2015Nymphayol increases glucose-stimulated insulin secretion by RIN-5F cells and GLUT4-mediated insulin sensitization in type 2 diabetic rat liver.Chemico-biological interactionsPubMed ↗
- 2015Lack of association between the insulin receptor substrates-1 Gly972Arg polymorphism and type-2 diabetes mellitus among Saudis from Eastern Saudi Arabia.Saudi medical journalPubMed ↗
- 2014Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity.DiabetesPubMed ↗
- 2014Insulin receptor substrate-1 (IRS-1) Gly927Arg: correlation with gestational diabetes mellitus in Saudi women.BioMed research internationalPubMed ↗