← New search
Phenotype profile

Fabry disease

SaudiVarKB evidence summary derived from retained literature mentions.

18Phenotype mentions
18Publications
6Associated gene records
5Associated variant records

Associated gene records

Co-mentioned in the same publications
GeneIdentifier / contextArticlesMentions
GLAHGNC:429688
MYBPC3HGNC:755122
MYH7HGNC:757722
TTRHGNC:1240522
PRKAG2HGNC:938611
PDE4DHGNC:878311

Associated variant records

Co-mentioned in the same publications
VariantIdentifier / contextArticlesMentions
p.Ala352Glyp.Ala352Gly11
G20210AG20210A11
N215SN215S11
p.Pro205Alap.Pro205Ala11
R112LR112L11

Associated population records

Co-mentioned in the same publications
PopulationIdentifier / contextArticlesMentions
Saudi Arabia22
Population recordCohort 2,06811
Population recordCohort 40411
Population recordCohort 6211
Population recordCohort 1511
Population recordCohort 4211
Saudi ArabiaCohort 61911
Population recordCohort 8811
Saudi ArabiaCohort 5111

Supporting publications

18 records
  1. 2026Impact of enzyme replacement therapy on hearing sensitivity in Fabry disease: A systematic review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery1 mentions
  2. 2026Expert opinion on facilitating intrafamily communication in rare diseases-Lessons from Fabry disease.Genetics in medicine open1 mentions
  3. 2026Signal Peptide Engineering and Codon Optimization to Enhance α-Gal A Activity for rAAV Gene Therapy of Fabry Disease.Journal of inherited metabolic disease1 mentions
  4. 2026Uncovering the gene variants in a global cohort of patients with unexplained increased left ventricular wall thickness using next-generation sequencing.BMC cardiovascular disorders1 mentions
  5. 2025Phenotypic Evolution in Fabry Disease: Our Experience in Indian Cohort.Indian journal of clinical biochemistry : IJCB1 mentions
  6. 2024Multinational experience with next-generation sequencing: opportunity to identify transthyretin cardiac amyloidosis and Fabry disease.Cardiovascular diagnosis and therapy1 mentions
  7. 2024Experts' Opinion in Fabry Disease Management and the Unmet Medical Need: The Saudi Perspective.Therapeutics and clinical risk management1 mentions
  8. 2023Asn215Ser, Ala143Thr, and Arg112Cys variants in α-galactosidase A protein confer stability loss in Fabry's disease.Journal of biomolecular structure & dynamics1 mentions
  9. 2023The Relationship between Serum TWEAK Levels and Carotid Intima-media Thickness in Patients with Fabry Disease.Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia1 mentions
  10. 2021The benefits and challenges of family genetic testing in rare genetic diseases-lessons from Fabry disease.Molecular genetics & genomic medicine1 mentions
  11. 2020The clinical utility of total concentration of urinary globotriaosylsphingosine plus its analogues in the diagnosis of Fabry disease.Clinica chimica acta; international journal of clinical chemistry1 mentions
  12. 2020Screening for Fabry disease among 619 hemodialysis patients in Saudi Arabia.Saudi medical journal1 mentions
  13. 2020The Prevalence of Fabry Disease Among Young Cryptogenic Stroke Patients.Cureus1 mentions
  14. 2019Diagnosis and treatment of the cardiovascular consequences of Fabry disease.QJM : monthly journal of the Association of Physicians1 mentions
  15. 2018Globotriaosylsphingosine (Lyso-Gb3) as a biomarker for cardiac variant (N215S) Fabry disease.Journal of inherited metabolic disease1 mentions
  16. 2017A novel mutation and in vivo confocal microscopic findings in Fabry disease.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society1 mentions
  17. 2008Genetics of ischemic stroke.Neurosciences (Riyadh, Saudi Arabia)1 mentions
  18. 2003Fabry kidney disease.Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia1 mentions