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Gene profile

NPHS1

HGNC:7908 · SaudiVarKB evidence summary derived from retained literature mentions.

13Gene mentions
13Publications
2Linked variants
4Associated phenotypes

Associated phenotypes

Co-mentioned in NPHS1 publications
PhenotypeIdentifierArticlesMentions
nephrotic syndrome1111
renal failure22
hypertension11
dyslipidemia11

Linked variants

Variants normalized to NPHS1
VariantHGVS / rsIDArticlesMentions
E117K11
P118L11

Population context

Reported in the same publications
Country / regionGroupCohortArticles
Not specified2001
Not specified201
Not specified481
Saudi Arabia31
Not specified581
Saudi Arabia621
Saudi Arabia · Riyadh2061
Saudi Arabia · Jeddah441

Supporting publications

13 records
  1. 2025Genomic Insights into Blood Pressure Regulation: Exploring Ion Channel and Transporter Gene Variations in Jordanian Hypertensive Individuals.Medicina (Kaunas, Lithuania)PubMed ↗
  2. 2023Genetic Studies in Infants with Congenital Nephrotic Syndrome: A Case Series.Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi ArabiaPubMed ↗
  3. 2023Collapsing Glomerulopathy in a Patient with a TRPC6 Mutation Presenting as Rapidly Progressive Glomerulonephritis: A Case Report and Review of the Literature.Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi ArabiaPubMed ↗
  4. 2023Effectiveness of Supramaximal Angiotensin-converting Enzyme Inhibition in Controlling Proteinuria in Congenital Nephrotic Syndrome with Cytomegalovirus Infection and an NPHS1 Mutation.Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi ArabiaPubMed ↗
  5. 2021The Frequency of Genetic Mutations in Pediatric Patients Diagnosed with Nephrotic Syndrome: A Single-Center Retrospective Study in Saudi Arabia.Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi ArabiaPubMed ↗
  6. 2020Genetic screening in children with challenging nephrotic syndrome.Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi ArabiaPubMed ↗
  7. 2019Genetics of congenital and infantile nephrotic syndrome.World journal of pediatrics : WJPPubMed ↗
  8. 2014Rapid detection of monogenic causes of childhood-onset steroid-resistant nephrotic syndrome.Clinical journal of the American Society of Nephrology : CJASNPubMed ↗
  9. 2013A molecular genetic analysis of childhood nephrotic syndrome in a cohort of Saudi Arabian families.Journal of human geneticsPubMed ↗
  10. 2013Does NPHS1 polymorphism modulate P118l mutation in NPHS2?Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi ArabiaPubMed ↗
  11. 2013Steroid-resistant nephrotic syndrome: impact of genetic testing.Annals of Saudi medicinePubMed ↗
  12. 2010A novel mutation in NPHS2 causing nephrotic syndrome in a Saudi Arabian family.NDT plusPubMed ↗
  13. 2003Congenital nephrotic syndrome.Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi ArabiaPubMed ↗