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Gene profile

TMPRSS6

HGNC:16517 · SaudiVarKB evidence summary derived from retained literature mentions.

9Gene mentions
9Publications
4Linked variants
1Associated phenotypes

Associated phenotypes

Co-mentioned in TMPRSS6 publications
PhenotypeIdentifierArticlesMentions
diabetes mellitus11

Linked variants

Variants normalized to TMPRSS6
VariantHGVS / rsIDArticlesMentions
rs855791rs85579122
rs141312rs14131211
rs235756rs23575611
rs2111833rs211183311

Population context

Reported in the same publications
Country / regionGroupCohortArticles
Saudi Arabia1
Saudi Arabia21
Saudi Arabia321
Not specified1131
Not specified5671
Saudi Arabia · Tabuk1
Not specified2931

Supporting publications

9 records
  1. 2023TMPRSS6 gene mutations in six Saudi families with iron refractory iron deficiency anemia.GenePubMed ↗
  2. 2021Genetic analysis of TMPRSS6 gene in Saudi female patients with iron deficiency anemia.Hematology/oncology and stem cell therapyPubMed ↗
  3. 2021Molecular analysis of homeostatic iron regulator, transmembrane protease serine-6, and BTB domain-containing protein-9 variants and iron parameters in blood donors.Bioscience reportsPubMed ↗
  4. 2021Role of TMPRSS6 rs855791 (T > C) polymorphism in reproductive age women with iron deficiency anemia from Lahore, Pakistan.Saudi journal of biological sciencesPubMed ↗
  5. 2021Association of SNPs within TMPRSS6 and BMP2 genes with iron deficiency status in Saudi Arabia.PloS onePubMed ↗
  6. 2020Study the association of transmembrane serine protease 6 gene polymorphisms with iron deficiency status in Saudi Arabia.GenePubMed ↗
  7. 2020Hepcidin, an overview of biochemical and clinical properties.SteroidsPubMed ↗
  8. 2017A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants.DiabetesPubMed ↗
  9. 2016Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals.American journal of human geneticsPubMed ↗