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Gene profile

FRRS1L

HGNC:1362 · SaudiVarKB evidence summary derived from retained literature mentions.

5Gene mentions
5Publications
0Linked variants
2Associated phenotypes

Associated phenotypes

Co-mentioned in FRRS1L publications
PhenotypeIdentifierArticlesMentions
epilepsyHP:000125033
intellectual disabilityHP:000124911

Linked variants

Variants normalized to FRRS1L
VariantHGVS / rsIDArticlesMentions

No normalized variants are linked to this gene.

Population context

Reported in the same publications
Country / regionGroupCohortArticles
Saudi Arabia1,0001

Supporting publications

5 records
  1. 2023Continuous Spikes and Waves During Sleep (CSWS), Severe Epileptic Encephalopathy, and Choreoathetosis due to Mutations in FRRS1L.Clinical EEG and neurosciencePubMed ↗
  2. 2022Identification of epilepsy concomitant candidate genes recognized in Saudi epileptic patients.European review for medical and pharmacological sciencesPubMed ↗
  3. 2017AMPA-receptor specific biogenesis complexes control synaptic transmission and intellectual ability.Nature communicationsPubMed ↗
  4. 2016Loss-of-Function Mutations in FRRS1L Lead to an Epileptic-Dyskinetic Encephalopathy.American journal of human geneticsPubMed ↗
  5. 2016Epileptic encephalopathy with continuous spike-and-wave during sleep maps to a homozygous truncating mutation in AMPA receptor component FRRS1L.Clinical geneticsPubMed ↗