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Gene profile

TRMT1

HGNC:25980 · SaudiVarKB evidence summary derived from retained literature mentions.

2Gene mentions
2Publications
0Linked variants
4Associated phenotypes

Associated phenotypes

Co-mentioned in TRMT1 publications
PhenotypeIdentifierArticlesMentions
intellectual disabilityHP:000124922
epilepsyHP:000125022
developmental delayHP:000126322
neurodevelopmental disorderHP:001275911

Linked variants

Variants normalized to TRMT1
VariantHGVS / rsIDArticlesMentions

No normalized variants are linked to this gene.

Population context

Reported in the same publications
Country / regionGroupCohortArticles
Not specified431

Supporting publications

2 records
  1. 2025Bi-allelic pathogenic variants in TRMT1 disrupt tRNA modification and induce a neurodevelopmental disorder.American journal of human geneticsPubMed ↗
  2. 2020An intellectual disability-associated missense variant in TRMT1 impairs tRNA modification and reconstitution of enzymatic activity.Human mutationPubMed ↗