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Phenotype profile

malaria

SaudiVarKB evidence summary derived from retained literature mentions.

153Phenotype mentions
100Publications
18Associated gene records
45Associated variant records

Associated gene records

Co-mentioned in the same publications
GeneIdentifier / contextArticlesMentions
G6PDHGNC:405766
HBBHGNC:482722
CD4HGNC:167811
TNFHGNC:1189211
GFAPHGNC:423511
VWFHGNC:1272611
CRPHGNC:236711
ABOHGNC:7911
CYP2B6HGNC:261511
PSMB9HGNC:954611
PNPHGNC:789211
TYROBPHGNC:1244911
PTPRCHGNC:966611
ACE2HGNC:1355711
CFHHGNC:488311
ITGB2HGNC:615511
LCP2HGNC:652911
CNR1HGNC:215911

Associated variant records

Co-mentioned in the same publications
VariantIdentifier / contextArticlesMentions
c.486-34delTc.486-34delT11
c.1311C>Tc.1311C>T11
c.1365-13T>Cc.1365-13T>C11
rs10118795rs1011879511
rs55726619rs5572661911
rs10815393rs1081539311
rs1332290rs133229011
rs1061170rs106117011
rs181209rs18120911
rs26528rs2652811
rs181206rs18120611
rs187238rs18723811
rs1946518rs194651811
rs4646116rs464611611
K26RK26R11
rs1238146879rs123814687911
P426AP426A11
N51IN51I11
S108NS108N11
C59RC59R11
A437GA437G11
K540EK540E11
rs3745274rs374527411
rs2279343rs227934311
rs28399499rs2839949911
rs2069705rs206970511
rs1061147rs106114711
p.Ala243Alap.Ala243Ala11
p.His402Tyrp.His402Tyr11
rs8177374rs817737411
rs5744292rs574429211
rs544354rs54435411
rs360714rs36071411
rs360728rs36072811
K189NK189N11
K189TK189T11
E208KE208K11
D281VD281V11
E401QE401Q11
R622IR622I11
T535MT535M11
A41LA41L11
C12LC12L11
A44LA44L11
A46RA46R11

Associated population records

Co-mentioned in the same publications

Supporting publications

100 records
  1. 2026Quantifying the fatal and non-fatal burden of disease associated with child growth failure, 2000-2023: a systematic analysis from the Global Burden of Disease Study 2023.The Lancet. Child & adolescent health1 mentions
  2. 2026Quantitative Estimation and Biosynthetic Pathways Study of Artemisinin in Artemisia tournefortiana: An Alternative Source for Artemisinin.Biomedical chromatography : BMC1 mentions
  3. 2026In silico profiling of the plasmodium knowlesi 32 kDa antigen: Diversity, epitope prediction, and structural modeling.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases1 mentions
  4. 2026Integrated diagnostic and host biomarker assessment of plasmodium infections in malaria-endemic Peshawar, Pakistan.Acta tropica1 mentions
  5. 2026Genetic diversity of plasmodium vivax merozoite surface protein 3α and β field isolates.Diagnostic microbiology and infectious disease1 mentions
  6. 2026Transfusion-transmitted infections among blood donors in Saudi Arabia: demographic and malaria risk differences by donation purpose.Hematology (Amsterdam, Netherlands)1 mentions
  7. 2026Plasmodium vivax infection in Duffy-negative populations in Sudan: a systematic review and meta-analysis of host-parasite genetic adaptation.Malaria journal1 mentions
  8. 2026Climate-sensitive infectious diseases in transition: a scoping review of key diseases and their epidemiology, data applications and mechanism of outbreak response in Saudi Arabia.BMC infectious diseases1 mentions
  9. 2026Association of interleukin-33 gene polymorphisms with susceptibility to Plasmodium falciparum infection.Malaria journal1 mentions
  10. 2026The origin, history, and resistance architecture of an invasive urban malaria mosquito in Africa.Science (New York, N.Y.)1 mentions
  11. 2025Ethnobotany, bioactive compounds and pharmacology of Syzygium guineense (Willd.) DC: A review.Journal of ethnopharmacology1 mentions
  12. 2025PHYLOGENETIC ANALYSIS OF AEDES AEGYPTI IN TAIF AND JEDDAH GOVERNORATES, SAUDI ARABIA.Journal of the American Mosquito Control Association1 mentions
  13. 2025Integrating malaria vaccine and CRISPR/Cas9 gene drive: a comprehensive strategy for accelerated malaria eradication.Malaria journal1 mentions
  14. 2025Leveraging genomic insights from the neglected malaria parasites P. malariae and P. ovale using selective whole genome amplification (SWGA) approach.BMC genomics1 mentions
  15. 2025In silico comparative analysis of genetic diversity and natural selection of Plasmodium knowlesi and Plasmodium vivax etramp11.2 gene.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases1 mentions
  16. 2025The origin, invasion history and resistance architecture of Anopheles stephensi in Africa.bioRxiv : the preprint server for biology1 mentions
  17. 2025Neuroprotective and antimalarial effects of Juglans regia leaf extracts in a murine model of cerebral malaria.Frontiers in veterinary science1 mentions
  18. 2025A Narrative Review on the Prevalence of Plasmodium falciparum Resistance Mutations to Antimalarial Drugs in Rwanda.Tropical medicine and infectious disease1 mentions
  19. 2025Determinants of Malaria Vaccine Acceptance: A Systematic Review and Meta-Analysis of Awareness, Acceptance, Hesitancy, and Willingness to Pay.Immunity, inflammation and disease1 mentions
  20. 2025Greenness assessment and phototoxicity of rose bengal and methylene blue on immature aquatic stages of malaria vector Anopheles pharoensis.Scientific reports1 mentions
  21. 2025Therapeutic Effects of Isopropyltoluene (p-Cymene) Alone and in Combination with Quinine Against Malaria Infection Through Modulation of Inflammation and Oxidative Stress.Vector borne and zoonotic diseases (Larchmont, N.Y.)1 mentions
  22. 2025Revolutionizing vaccination: the marvel of nanovaccination technology.Molecular biology reports1 mentions
  23. 2025Differential Impacts of Extreme Weather Events on Vector-Borne Disease Transmission Across Urban and Rural Settings: A Scoping Review.Healthcare (Basel, Switzerland)1 mentions
  24. 2025Global, regional, and national sepsis incidence and mortality, 1990-2021: a systematic analysis.The Lancet. Global health1 mentions
  25. 2025Distribution of HbS, HbC variants, ABO blood groups in relation to malaria infection among Saudi children in Jazan region.Acta tropica1 mentions
  26. 2025Transfusion-transmitted infections among northern Saudi blood donors: Seroprevalence and risk factors.Medicine1 mentions
  27. 2025Genetic diversity and haplotype structure of the CelTOS gene in Plasmodium falciparum from Jazan Province, Saudi Arabia: implications for vaccine development and malaria elimination.Frontiers in cellular and infection microbiology1 mentions
  28. 2025Duffy Antigen Receptor for Chemokines (DARC) Polymorphisms and Susceptibility to Plasmodium Vivax Malaria in Sudan: a Case - Control Study.Materia socio-medica1 mentions
  29. 2025The Impact of Aging on Organ Systems in Sickle Cell Disease: a Comparative Review of Physiological Adaptation and Dysfunction.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology1 mentions
  30. 2024Coding Therapeutic Nucleic Acids from Recombinant Proteins to Next-Generation Vaccines: Current Uses, Limitations, and Future Horizons.Molecular biotechnology1 mentions
  31. 2024Identification of novel compounds and repurposing of FDA drugs for 1-deoxy-D-xylulose 5-phosphate reductoisomerase enzyme of Plasmodium falciparum to combat malaria resistance.International journal of biological macromolecules1 mentions
  32. 2024Joint quantile disease mapping with application to malaria and G6PD deficiency.Royal Society open science1 mentions
  33. 2024Structural exploration of the PfBLM Helicase-ATP Binding Domain and implications in the quest for antimalarial therapies.Journal of vector borne diseases1 mentions
  34. 2024Genetic analysis and molecular basis of G6PD deficiency among malaria patients in Thailand: implications for safe use of 8-aminoquinolines.Malaria journal1 mentions
  35. 2024Knowledge and Awareness of Systemic Lupus Erythematosus Among the Population of Jeddah, Saudi Arabia: A Cross-Sectional Study.Cureus1 mentions
  36. 2024Unveiling potential repurposed drug candidates for Plasmodium falciparum through in silico evaluation: A synergy of structure-based approaches, structure prediction, and molecular dynamics simulations.Computational biology and chemistry1 mentions
  37. 2024Awareness of sickle cell disease among nursing undergraduates in Farasan: Its interference with malaria.Journal of family medicine and primary care1 mentions
  38. 2024Exploring mosquito abundance and Plasmodium infection through nested-PCR: implications for disease surveillance and control.Scientific reports1 mentions
  39. 2024Analyzing the impact of pesticides on the indus river: contamination levels in water, sediment, fish, and associated human health risks.Environmental geochemistry and health1 mentions
  40. 2024Efficient deep learning-based approach for malaria detection using red blood cell smears.Scientific reports1 mentions
  41. 2024Transcriptional responses of brain endothelium to Plasmodium falciparum patient-derived isolates in vitro.Microbiology spectrum1 mentions
  42. 2024Zinc oxide nanoparticles loaded with linalool as a potential control agent of malaria infection.Acta tropica1 mentions
  43. 2024Identification of complex Plasmodium falciparum genetic backgrounds circulating in Africa: a multicountry genomic epidemiology analysis.The Lancet. Microbe1 mentions
  44. 2024Investigation of Wright Blood Group Alleles and Genotypes in Malaria-Endemic Area in Southwestern Saudi Arabia.International journal of general medicine1 mentions
  45. 2024Recent Advances in the Treatment of Malaria.Pharmaceutics1 mentions
  46. 2023Approaching COVID-19 with epidemiological genomic surveillance and the sustainability of biodiversity informatics in Africa.Journal of medical virology1 mentions
  47. 2023The Prevalence of Transfusion-Transmitted Infection Markers among Blood Donors at Saudi Hospital, Makkah.Clinical laboratory1 mentions
  48. 2023Pf7: an open dataset of Plasmodium falciparum genome variation in 20,000 worldwide samples.Wellcome open research1 mentions
  49. 2023Creating and Validating Ligase Primers to Detect Single Nucleotide Polymorphisms Associated with Atovaquone Resistance in Plasmodium falciparum.The American journal of tropical medicine and hygiene1 mentions
  50. 2023Anti-phosphatidylserine antibody levels are low in multigravid pregnant women in a malaria-endemic area in Nigeria, and do not correlate with anti-VAR2CSA antibodies.Frontiers in cellular and infection microbiology1 mentions
  51. 2023A Critical Review on Human Malaria and Schistosomiasis Vaccines: Current State, Recent Advancements, and Developments.Vaccines1 mentions
  52. 2023IgG4 Antibodies Induced by Repeated Vaccination May Generate Immune Tolerance to the SARS-CoV-2 Spike Protein.Vaccines1 mentions
  53. 2023PfAP2-MRP DNA-binding protein is a master regulator of parasite pathogenesis during malaria parasite blood stages.bioRxiv : the preprint server for biology1 mentions
  54. 2023Association between interleukin-27 gene polymorphisms and Plasmodium falciparum Malaria.Innate immunity1 mentions
  55. 2023In Silico Analysis Reveals High Levels of Genetic Diversity of Plasmodium knowlesi Cell Traversal Protein for Ookinetes and Sporozoites (PkCelTOS) in Clinical Samples.Tropical medicine and infectious disease1 mentions
  56. 2023Exploring the host factors affecting asymptomatic Plasmodium falciparum infection: insights from a rural Burkina Faso study.Malaria journal1 mentions
  57. 2023Antimalarial drug discovery against malaria parasites through haplopine modification: An advanced computational approach.Journal of cellular and molecular medicine1 mentions
  58. 2023Peripheral and Placental Prevalence of Sulfadoxine-Pyrimethamine Resistance Markers in Plasmodium falciparum among Pregnant Women in Southern Province, Rwanda.The American journal of tropical medicine and hygiene1 mentions
  59. 2023Identification of useful biomolecular markers in kidney renal clear cell carcinoma: an in silico and in vitro analysis-based study.American journal of translational research1 mentions
  60. 2023DNA-binding protein PfAP2-P regulates parasite pathogenesis during malaria parasite blood stages.Nature microbiology1 mentions
  61. 2023Different PfEMP1-expressing Plasmodium falciparum variants induce divergent endothelial transcriptional responses during co-culture.PloS one1 mentions
  62. 2022Plasmodium falciparum histidine rich protein 2 (pfhrp2): an additional genetic marker suitable for anti-malarial drug efficacy trials.Malaria journal1 mentions
  63. 2022Patterns, Outcomes and Predictors of Pediatric Medical Admissions at Gadarif Hospital in Eastern Sudan.Frontiers in pediatrics1 mentions
  64. 2022Genetic Diversity, Repeat Motifs, and Natural Selection at the C-Terminal Knob-Associated Histidine Rich Protein (KAHRP) of Plasmodium falciparum Clinical Samples from Saudi Arabia.Journal of tropical medicine1 mentions
  65. 2022Geographical distribution and genetic diversity of Plasmodium vivax reticulocyte binding protein 1a correlates with patient antigenicity.PLoS neglected tropical diseases1 mentions
  66. 2022Genetic Diversity and Population Genetic Analysis of Plasmodium falciparum Thrombospondin Related Anonymous Protein (TRAP) in Clinical Samples from Saudi Arabia.Genes1 mentions
  67. 2022Prevalence of Transfusion-Transmitted Infections (HCV, HIV, Syphilis and Malaria) in Blood Donors: A Large-Scale Cross-Sectional Study.Pathogens (Basel, Switzerland)1 mentions
  68. 2022The prevalence of sickling abnormality in Oman: A review of relevant publications.Acta bio-medica : Atenei Parmensis1 mentions
  69. 2022Phase 3 evaluation of an innovative simple molecular test for the diagnosis of malaria in different endemic and health settings in sub-Saharan Africa (DIAGMAL).PloS one1 mentions
  70. 2022In silico study to predict promiscuous T cell and B cell-epitopes derived from the vaccine candidate antigens of Plasmodium vivax binding to MHC class-II alleles.Journal of vector borne diseases1 mentions
  71. 2022Demographic and Selection Histories of Populations Across the Sahel/Savannah Belt.Molecular biology and evolution1 mentions
  72. 2022Prevalence of anemia in pre-school tribal children with reference to parasitic infections and nutritional impact.Journal of Taibah University Medical Sciences1 mentions
  73. 2022Creation and preclinical evaluation of genetically attenuated malaria parasites arresting growth late in the liver.NPJ vaccines1 mentions
  74. 2022Plasmodium falciparum Malaria Susceptibility and Severity: Influence of MyD88-Adaptor-Like Gene (rs8177374) Polymorphism.Infection and drug resistance1 mentions
  75. 2022Phytoconstituents Assisted Biofabrication of Copper Oxide Nanoparticles and Their Antiplasmodial, and Antilarval Efficacy: A Novel Approach for the Control of Parasites.Molecules (Basel, Switzerland)1 mentions
  76. 2022Prevalence of transfusion-transmitted infections in Saudi Arabia blood donors: A nationwide, cross-sectional study.Saudi medical journal1 mentions
  77. 2021An Analysis of Racial and Ethnic Backgrounds Within the CASiRe International Cohort of Sickle Cell Disease Patients: Implications for Disease Phenotype and Clinical Research.Journal of racial and ethnic health disparities1 mentions
  78. 2021Chloroquine and Hydroxychloroquine Interact Differently with ACE2 Domains Reported to Bind with the Coronavirus Spike Protein: Mediation by ACE2 Polymorphism.Molecules (Basel, Switzerland)1 mentions
  79. 2021An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples.Wellcome open research1 mentions
  80. 2021Plasmodium vinckei genomes provide insights into the pan-genome and evolution of rodent malaria parasites.BMC biology1 mentions
  81. 2021Associations of Single Nucleotide Polymorphisms in IL-18 Gene with Plasmodium falciparum-Associated Malaria.Journal of inflammation research1 mentions
  82. 2021Seroprevalence of Transfusion-Transmitted Infections among Voluntary and Replacement Blood Donors at the Peshawar Regional Blood Centre, Khyber Pakhtunkhwa, Pakistan.Journal of laboratory physicians1 mentions
  83. 2021New insights into the spread of resistance to artemisinin and its analogues.Journal of global antimicrobial resistance1 mentions
  84. 2021Significant differences in FcγRIIa, FcγRIIIa and FcγRIIIb genes polymorphism and anti-malarial IgG subclass pattern are associated with severe Plasmodium falciparum malaria in Saudi children.Malaria journal1 mentions
  85. 2021The return of chloroquine-sensitive Plasmodium falciparum parasites in Jazan region, southwestern Saudi Arabia over a decade after the adoption of artemisinin-based combination therapy: analysis of genetic mutations in the pfcrt gene.Parasitology research1 mentions
  86. 2021The genome of the zoonotic malaria parasite Plasmodium simium reveals adaptations to host switching.BMC biology1 mentions
  87. 2021Identification of immunodominant epitopes in allelic variants VK210 and VK247 of Plasmodium Vivax Circumsporozoite immunogen.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases1 mentions
  88. 2021Epidemiology of community-acquired acute kidney injury in children as seen in an emergency room of Tertiary Hospital in South-South Nigeria.Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia1 mentions
  89. 2021Identification, Mapping, and Genetic Diversity of Novel Conserved Cross-Species Epitopes of RhopH2 in Plasmodium knowlesi With Plasmodium vivax.Frontiers in cellular and infection microbiology1 mentions
  90. 2020Targeted deep amplicon sequencing of kelch 13 and cytochrome b in Plasmodium falciparum isolates from an endemic African country using the Malaria Resistance Surveillance (MaRS) protocol.Parasites & vectors1 mentions
  91. 2020Immune responses in liver and spleen against Plasmodium yoelii pre-erythrocytic stages in Swiss mice model.Journal of advanced research1 mentions
  92. 2020Influx of diverse, drug resistant and transmissible Plasmodium falciparum into a malaria-free setting in Qatar.BMC infectious diseases1 mentions
  93. 2020Uncomplicated falciparum malaria among schoolchildren in Bajil district of Hodeidah governorate, west of Yemen: association with anaemia and underweight.Malaria journal1 mentions
  94. 2020Kelch 13-propeller polymorphisms in Plasmodium falciparum from Jazan region, southwest Saudi Arabia.Malaria journal1 mentions
  95. 2020Increased prevalence of pfdhfr and pfdhps mutations associated with sulfadoxine-pyrimethamine resistance in Plasmodium falciparum isolates from Jazan Region, Southwestern Saudi Arabia: important implications for malaria treatment policy.Malaria journal1 mentions
  96. 2020Evaluation of Annona muricata Acetogenins as Potential Anti-SARS-CoV-2 Agents Through Computational Approaches.Frontiers in chemistry1 mentions
  97. 2019Plasmodium life cycle stage classification based quantification of malaria parasitaemia in thin blood smears.Microscopy research and technique1 mentions
  98. 2019Complement factor H gene polymorphisms and vivax malaria associated thrombotic microangiopathy.Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia1 mentions
  99. 2019Whole genome sequencing of amplified Plasmodium knowlesi DNA from unprocessed blood reveals genetic exchange events between Malaysian Peninsular and Borneo subpopulations.Scientific reports1 mentions
  100. 2019Evolution of Plasmodium falciparum drug resistance genes following artemisinin combination therapy in Sudan.Transactions of the Royal Society of Tropical Medicine and Hygiene1 mentions