CXCR2
HGNC:6027 · SaudiVarKB evidence summary derived from retained literature mentions.
9Gene mentions
9Publications
6Linked variants
4Associated phenotypes
Associated phenotypes
Co-mentioned in CXCR2 publications| Phenotype | Identifier | Articles | Mentions |
|---|---|---|---|
| autism spectrum disorder | HP:0000729 | 3 | 3 |
| neurodevelopmental disorder | HP:0012759 | 2 | 2 |
| COVID-19 | — | 1 | 1 |
| infertility | — | 1 | 1 |
Linked variants
Variants normalized to CXCR2Population context
Reported in the same publications| Country / region | Group | Cohort | Articles |
|---|---|---|---|
| Not specified | — | 19 | 1 |
| Tabuk | — | — | 1 |
Supporting publications
9 records- 2025Seven Hub Genes Associated with Huntington's Disease and Diagnostic and Therapeutic Potentials Identified by Computational Biology.Omics : a journal of integrative biologyPubMed ↗
- 2024Molecular Determination of Tumor Necrosis Factor-alpha, Interleukin-8, Interleukin-10, and C-X-C Chemokine Receptor-2 Genetic Variations and their Association with Disease Susceptibility and Mortality in COVID-19 Patients.Current genomicsPubMed ↗
- 2024Exploring the Association of Biochemical Characterization and Genetic Determinants of TNF-α, CXCR2, and CCR5 Delta 32 Mutation with Predisposition to Polycystic Ovary Syndrome.Life (Basel, Switzerland)PubMed ↗
- 2023A potent and selective CXCR2 antagonist improves neuroimmune dysregulation through the inhibition of NF-κB and notch inflammatory signaling in the BTBR mouse model of autism.Journal of neuroimmunologyPubMed ↗
- 2022CXCR2 antagonist SB332235 mitigates deficits in social behavior and dysregulation of Th1/Th22 and T regulatory cell-related transcription factor signaling in male BTBR T+ Itpr3tf/J mouse model of autism.Pharmacology, biochemistry, and behaviorPubMed ↗
- 2021Senescence-Associated Secretory Phenotype Suppression Mediated by Small-Sized Mesenchymal Stem Cells Delays Cellular Senescence through TLR2 and TLR5 Signaling.CellsPubMed ↗
- 2021Loss of Neutrophil Homing to the Periodontal Tissues Modulates the Composition and Disease Potential of the Oral Microbiota.Infection and immunityPubMed ↗
- 2020CXCR2 signaling promotes secretory cancer-associated fibroblasts in pancreatic ductal adenocarcinoma.FASEB journal : official publication of the Federation of American Societies for Experimental BiologyPubMed ↗
- 2018Upregulation of peripheral CXC and CC chemokine receptor expression on CD4+ T cells is associated with immune dysregulation in children with autism.Progress in neuro-psychopharmacology & biological psychiatryPubMed ↗