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Gene profile

TSC2

HGNC:12363 · SaudiVarKB evidence summary derived from retained literature mentions.

14Gene mentions
14Publications
0Linked variants
7Associated phenotypes

Associated phenotypes

Co-mentioned in TSC2 publications
PhenotypeIdentifierArticlesMentions
epilepsyHP:000125077
polycystic kidney disease22
intellectual disabilityHP:000124911
cystic fibrosis11
developmental delayHP:000126311
renal failure11
colorectal cancer11

Linked variants

Variants normalized to TSC2
VariantHGVS / rsIDArticlesMentions

No normalized variants are linked to this gene.

Population context

Reported in the same publications
Country / regionGroupCohortArticles
Saudi Arabia1
Not specified231
Saudi Arabia881
Saudi Arabia111
Not specified381
Saudi Arabia611
Saudi Arabia161
Saudi Arabia1,0001

Supporting publications

14 records
  1. 2026Early use of everolimus for neonatal cardiac rhabdomyoma: a pharmacotherapeutic case with pharmacist-led monitoring.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical SocietyPubMed ↗
  2. 2026Genotypic and phenotypic features of 23 Egyptian patients with tuberous sclerosis complex.BMC pediatricsPubMed ↗
  3. 2025Vitexin's Role in Colon Cancer Apoptosis: AMPK/mTOR Pathway Modulation Explored Through Experimental and Computational Approaches.Recent patents on anti-cancer drug discoveryPubMed ↗
  4. 2025Renal Cell Carcinoma in a Girl With Tuberous Sclerosis Due to a New Mutation.Journal of medical casesPubMed ↗
  5. 2024Sporadic subependymal giant cell astrocytoma with somatic TSC2 mutation: A case report.Neurosciences (Riyadh, Saudi Arabia)PubMed ↗
  6. 2024Review of the spectrum of tuberous sclerosis complex: The Saudi Arabian Experience.Neurosciences (Riyadh, Saudi Arabia)PubMed ↗
  7. 2024Central nervous system manifestations of tuberous sclerosis complex: A single centre experience in Qatar.Saudi medical journalPubMed ↗
  8. 2022Diagnostic features of tuberous sclerosis complex: case report and literature review.Quantitative imaging in medicine and surgeryPubMed ↗
  9. 2022Identification of epilepsy concomitant candidate genes recognized in Saudi epileptic patients.European review for medical and pharmacological sciencesPubMed ↗
  10. 2022High incidence of PI3K pathway gene mutations in South Indian cervical cancers.Cancer geneticsPubMed ↗
  11. 2022Identification and Characterization of Novel Mutations in Chronic Kidney Disease (CKD) and Autosomal Dominant Polycystic Kidney Disease (ADPKD) in Saudi Subjects by Whole-Exome Sequencing.Medicina (Kaunas, Lithuania)PubMed ↗
  12. 2021The Phenotypic Spectrum of Tuberous Sclerosis Complex: A Canadian Cohort.Child neurology openPubMed ↗
  13. 2019Exome sequencing of Saudi Arabian patients with ADPKD.Renal failurePubMed ↗
  14. 2018Tuberous Sclerosis Complex: Clinical Spectrum and Epilepsy: A Retrospective Chart Review Study.Translational neurosciencePubMed ↗