ulcerative colitis
SaudiVarKB evidence summary derived from retained literature mentions.
490Phenotype mentions
100Publications
50Associated gene records
10Associated variant records
Associated gene records
Co-mentioned in the same publications| Gene | Identifier / context | Articles | Mentions |
|---|---|---|---|
| NLRP3 | HGNC:16400 | 17 | 17 |
| TLR4 | HGNC:11850 | 12 | 12 |
| STAT3 | HGNC:11364 | 9 | 9 |
| SIRT1 | HGNC:14929 | 7 | 7 |
| MPO | HGNC:7218 | 5 | 5 |
| BCL2 | HGNC:990 | 5 | 5 |
| BAX | HGNC:959 | 4 | 4 |
| IL10 | HGNC:5962 | 3 | 3 |
| TFAM | HGNC:11741 | 3 | 3 |
| PCNA | HGNC:8729 | 3 | 3 |
| MUC2 | HGNC:7512 | 3 | 3 |
| TNF | HGNC:11892 | 2 | 2 |
| LRRK2 | HGNC:18618 | 2 | 2 |
| EGFR | HGNC:3236 | 2 | 2 |
| DKK1 | HGNC:2891 | 2 | 2 |
| CXCL1 | HGNC:4602 | 2 | 2 |
| HMGB1 | HGNC:4983 | 2 | 2 |
| CPT1A | HGNC:2328 | 1 | 1 |
| CXCL9 | HGNC:7098 | 1 | 1 |
| APOE | HGNC:613 | 1 | 1 |
| CFTR | HGNC:1884 | 1 | 1 |
| CRP | HGNC:2367 | 1 | 1 |
| TYK2 | HGNC:12440 | 1 | 1 |
| IRAK4 | HGNC:17967 | 1 | 1 |
| RIPK1 | HGNC:10019 | 1 | 1 |
| KRAS | HGNC:6407 | 1 | 1 |
| BRAF | HGNC:1097 | 1 | 1 |
| CXCL8 | HGNC:6025 | 1 | 1 |
| AKT1 | HGNC:391 | 1 | 1 |
| MALAT1 | HGNC:29665 | 1 | 1 |
| EIF2B3 | HGNC:3259 | 1 | 1 |
| RAD51 | HGNC:9817 | 1 | 1 |
| FAP | HGNC:3590 | 1 | 1 |
| PCK1 | HGNC:8724 | 1 | 1 |
| JAK2 | HGNC:6192 | 1 | 1 |
| SLC26A3 | HGNC:3018 | 1 | 1 |
| NOD2 | HGNC:5331 | 1 | 1 |
| ITGA4 | HGNC:6140 | 1 | 1 |
| CARD9 | HGNC:16391 | 1 | 1 |
| MMP2 | HGNC:7166 | 1 | 1 |
| MMP9 | HGNC:7176 | 1 | 1 |
| NCF2 | HGNC:7661 | 1 | 1 |
| RAC2 | HGNC:9802 | 1 | 1 |
| JAK1 | HGNC:6190 | 1 | 1 |
| TRAF6 | HGNC:12036 | 1 | 1 |
| LAMP2 | HGNC:6501 | 1 | 1 |
| CD200R1 | HGNC:24235 | 1 | 1 |
| IL4 | HGNC:6014 | 1 | 1 |
| SLC22A5 | HGNC:10969 | 1 | 1 |
| CYBB | HGNC:2578 | 1 | 1 |
Associated variant records
Co-mentioned in the same publicationsAssociated population records
Co-mentioned in the same publicationsSupporting publications
100 records- 2026AQP9 and IFITM1 as drivers of immune infiltration and tumor progression in IBD-associated colorectal cancer: from computational insights to experimental validation.Naunyn-Schmiedeberg's archives of pharmacology1 mentions
- 2026Ultraprocessed Grains and Risk of Inflammatory Bowel Disease: Results From the Prospective Urban Rural Epidemiology Study.The American journal of gastroenterology1 mentions
- 2026Anti-inflammatory effect of pirfenidone compared to dexamethasone in ulcerative colitis model induced by acetic acid in rats: involvement of miR-146a and TLR4/NF-κB signaling.Naunyn-Schmiedeberg's archives of pharmacology1 mentions
- 2026Cost calculation model of introducing Upadacitinib and Risankizumab for adult ulcerative colitis and Crohn's disease in the Kingdom of Saudi Arabia.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2026Patterns and predictors of biologic therapy switching in inflammatory bowel disease at a tertiary care center: A retrospective observational study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2026The Impact of Disease Activity and Medications on Pregnancy and Fetal Outcomes in Women With Inflammatory Bowel Disease: A Cohort Study From the IBD-ME Group.Journal of gastroenterology and hepatology1 mentions
- 2026Inflammatory Bowel Disease in Children and Young People Living With Overweight or Obesity: A Critical Narrative Review.Obesity reviews : an official journal of the International Association for the Study of Obesity1 mentions
- 2026Protective Effects of Herbacetin in Experimental Colitis: Targeting NF-κB and NLRP3 Pathways.Drug development research1 mentions
- 2026Effectiveness and safety of upadacitinib in refractory pediatric inflammatory bowel disease: A single-arm meta-analysis of observational studies.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2026Trimetazidine Attenuates Ulcerative Colitis-Linked Extrapyramidal Dysfunction by Mediated Dectin-1/LRRK2/α-Synuclein Autophagy Axis.Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada1 mentions
- 2026Co-Occurrence of Inflammatory Bowel Disease in Patients with Vitiligo: A Systematic Review and Meta-Analysis.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology1 mentions
- 2026Association between spicy food consumption and inflammatory bowel disease: A case-control study from Saudi Arabia.Nutrition (Burbank, Los Angeles County, Calif.)1 mentions
- 2026Optimizing vedolizumab therapy in ulcerative colitis: A critical synthesis of trial evidence and the emerging role of artificial intelligence.PLOS digital health1 mentions
- 2026Redrawing the gut map: evolving probiotic approaches to microbiota modulation in inflammatory bowel disease.Antonie van Leeuwenhoek1 mentions
- 2026Repurposing alogliptin for ulcerative colitis: involvement of MicroRNAs, anti-inflammatory, and barrier-restoring mechanisms.Naunyn-Schmiedeberg's archives of pharmacology1 mentions
- 2026Ulcerative colitis, pathophysiological mechanisms and drug repurposing: a new therapeutic dawn-narrative review.Inflammopharmacology1 mentions
- 2026Mirikizumab four-year sustained and durable efficacy and safety in ulcerative colitis: Final findings from the LUCENT-3 open-label extension study.Inflammatory bowel diseases1 mentions
- 2026Modulation of mTOR, NLRP3, and Nrf2/HO-1 signaling by atorvastatin and nitazoxanide in experimental ulcerative colitis.Naunyn-Schmiedeberg's archives of pharmacology1 mentions
- 2026Characteristics, Complications, Comorbidities, and Other Manifestations of Inflammatory Bowel Disease: A 7-Year Tertiary Center Experience.Clinics and practice1 mentions
- 2026Clinical consequences of delayed recognition of gastrointestinal basidiobolomycosis: a case series.Journal of surgical case reports1 mentions
- 2026Colon-targeted pH-responsive tofacitinib beads improve ulcerative colitis outcomes with lower systemic exposure.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society1 mentions
- 2026Pyoderma Gangrenosum of the Eyelid: A Challenging Case.The American journal of case reports1 mentions
- 2026Bacterial and fungal biomarkers in irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD): trans-kingdom interactions, Blastocystis carriage, and enterotype-succinotype stratification.Gut pathogens1 mentions
- 2026Sphingosine 1-Phosphate (S1P) Receptor Modulators as an Induction and Maintenance Therapy for Moderate to Severe Ulcerative Colitis: A Systematic Review and Meta-analysis of Randomized Controlled Trials.Digestive diseases and sciences1 mentions
- 2026Harnessing Nanocarriers to Modulate Gut Inflammation: A New Era in IBD Management.Recent advances in inflammation & allergy drug discovery1 mentions
- 2026High-precision classification of WCE-based gastrointestinal abnormality using a fusion deep learning approach.Scientific reports1 mentions
- 2026Mode of birth and risk of inflammatory bowel disease in offspring: an updated systematic review and meta-analysis.Frontiers in reproductive health1 mentions
- 2026Adjunctive Pentoxifylline Enhances Clinical Remission and Reduces Inflammatory Biomarkers in Mild-to-Moderate Ulcerative Colitis: A Randomized Double-Blind Placebo-Controlled Pilot Trial.Pharmaceuticals (Basel, Switzerland)1 mentions
- 2026HOCl-Mediated Bromothymol Blue Bleaching and Carbon Dot Fluorescence Recovery for Fecal Myeloperoxidase Quantification in Ulcerative Colitis.Journal of fluorescence1 mentions
- 2026Prevalence, patient characteristics, and outcomes of high-dose upadacitinib in inflammatory bowel disease.Therapeutic advances in gastroenterology1 mentions
- 2026Medication Use and Guideline Adherence in Inflammatory Bowel Disease Management: A Retrospective Study from a Tertiary Care Hospital in Pakistan (2019-2024).International journal of general medicine1 mentions
- 2026Lactose-decorated, alginate-coated chitosan nanoparticles loaded with Coomassie Brilliant Blue G-250 protect colonic barrier integrity in experimental colitis.Tissue & cell1 mentions
- 2026STRIDE-II treatment target achievement in inflammatory bowel disease: a cross-sectional study from a tertiary IBD centre in the United Arab Emirates.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2026Disease burden of inflammatory bowel disease and subtypes in older adults in 172 high- and middle-income countries: Trends from 2000 to 2023 and projections to 2040.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2026Patient Preferences for Virtual Versus In-Person Care in Inflammatory Bowel Disease: A Cross-Sectional Study.Telemedicine journal and e-health : the official journal of the American Telemedicine Association1 mentions
- 2026Patient preferences toward the attributes of treatment used for inflammatory bowel disease in Saudi Arabia: Subgroup analysis from an international multicenter discrete choice experiment.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2026Spinosin Attenuates DSS-Induced Ulcerative Colitis in Rats in Association with Increased Nrf2/HO-1 and Reduced TLR4/NFKB1-Related Inflammatory Markers.European journal of pharmacology1 mentions
- 2025Ustekinumab Drug Levels and Outcomes in Inflammatory Bowel Disease.Journal of clinical gastroenterology1 mentions
- 2025Clinical effectiveness and safety of ustekinumab in youth with refractory inflammatory bowel disease: A retrospective cohort study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2025Periodontitis increases the risk of gastrointestinal dysfunction: an update on the plausible pathogenic molecular mechanisms.Critical reviews in microbiology1 mentions
- 2025Bacterial dysbiosis in newly diagnosed treatment naïve pediatric ulcerative colitis in Saudi Arabia.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2025Leveraging thiol-functionalized biomucoadhesive hybrid nanoliposome for local therapy of ulcerative colitis.Biomaterials1 mentions
- 2025The effectiveness of vedolizumab in advanced therapy-experienced ulcerative colitis patients: Real world data from the Inflammatory Bowel Disease of the Middle East (IBD-ME) Registry group.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2025The treatment naïve microbiome of pediatric ulcerative colitis and microbial therapeutics: A humbling challenge.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2025Gut fungal profile in new onset treatment-naïve ulcerative colitis in Saudi children.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2025Preparation, Characterization, and In Vitro Evaluation of Chlorogenic Acid Loaded Hydrogel Beads for the Management of Ulcerative Colitis.Assay and drug development technologies1 mentions
- 2025Acute Severe Ulcerative Colitis: An International Delphi Consensus on Clinical Trial Design and Endpoints.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association1 mentions
- 2025Comparison of long-term outcomes of infliximab and adalimumab therapy in biologic-naive patients with ulcerative colitis.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2025Coexisting autoimmune disorders among patients with inflammatory bowel disease at a tertiary center in Saudi Arabia: A cross-sectional study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2025Hepatobiliary manifestations of inflammatory bowel disease in Saudi Arabia: A retrospective analysis.Saudi medical journal1 mentions
- 2025Prevalence and clinical implications of anti-drug antibody formation and serum drug levels among patients with IBD receiving anti-TNF therapy: A cross-sectional study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2025Evaluating the efficacy of nano-cyclosporine A in mice model of ulcerative colitis: a meta-analysis.Naunyn-Schmiedeberg's archives of pharmacology1 mentions
- 2025Protective Role of Nano-encapsulated Bifidobacterium breve, Bacilllus coagulans, and Lactobacillus plantarum in Colitis Model: Insights Toward Propagation of Short-Chain Fatty Acids and Reduction of Exaggerated Inflammatory and Oxidative Response.Probiotics and antimicrobial proteins1 mentions
- 2025Real-world assessment of effectiveness and safety of filgotinib in 286 patients with ulcerative colitis in 9 UK centres.Drugs in context1 mentions
- 2025Commentary on the real-world effectiveness of vedolizumab in therapy-experienced ulcerative colitis: A response to Azzam et al .Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2025Dihydroartemisinin attenuates acetic acid-induced ulcerative colitis in rats: Suppression of inflammation and modulation of NFκβ/TNF-α/RIPK1-mediated necroptosis and apoptosis.Tissue & cell1 mentions
- 2025Multifunctional chrysin-loaded gallic acid-glycerol monostearate conjugate-based injectable hydrogel for targeted inhibition of hypoxia-induced NLRP3 inflammasome in ulcerative colitis.Biomaterials science1 mentions
- 2025Colorectal Neoplasia in Inflammatory Bowel Disease.Cancers1 mentions
- 2025High-Throughput Whole-Exome Sequencing and Large-Scale Computational Analysis to Identify the Genetic Biomarkers to Predict the Vedolizumab Response Status in Inflammatory Bowel Disease Patients from Saudi Arabia.Biomedicines1 mentions
- 2025Chloride channels and mast cell function: pioneering new frontiers in IBD therapy.Molecular and cellular biochemistry1 mentions
- 2025Comment on "Gut fungal profile in new onset treatment-naïve ulcerative colitis in Saudi children".Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2025Promising protective treatment potential of endophytic bacterium Rhizobium aegyptiacum for ulcerative colitis in rats.Journal of Zhejiang University. Science. B1 mentions
- 2025Mapping the Ulcerative Colitis Patient Journey in Saudi Arabia from Healthcare Professionals' Perspective: A Cross-Sectional Non-Interventional Study.Journal of clinical medicine1 mentions
- 2025The adjunctive role of metformin in patients with mild to moderate ulcerative colitis: a randomized controlled study.Frontiers in pharmacology1 mentions
- 2025Modulation of FOXO3a Nuclear Localization by Linagliptin (BI-1356) reveals a new therapeutic target in chronic ulcerative colitis.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences1 mentions
- 2025Gut virome profile in new onset treatment naïve Saudi children with ulcerative colitis.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2025Pioglitazone mitigates acetic acid-induced colitis in rats via epigenetic-modulation and antioxidant mechanisms.Naunyn-Schmiedeberg's archives of pharmacology1 mentions
- 2025Impact of Microbiota Diversity on Inflammatory Bowel Disease.Microorganisms1 mentions
- 2025Beta-Sitosterol-Conjugated Sinapic Acid-Engineered Nanoliposome: Biomucoadhesive and Enzyme-Responsive Targeted Oral Therapy in Ulcerative Colitis.ACS applied materials & interfaces1 mentions
- 2025Bioactive chitosan-BSA Maillard-derived chrysin-loaded nanoparticles: A gastroprotective, biomucoadhesive approach for enhanced oral therapy in ulcerative colitis.Carbohydrate polymers1 mentions
- 2025Repurposing Atorvastatin, HMGCO-A Reductase Inhibitor, in Patients with Ulcerative Colitis: A Randomized Controlled Study.Journal of clinical medicine1 mentions
- 2025Expression Profile of Serum CircFUNDC1 and CircUHRF1 Can Differentiate Between Colorectal Cancer and Inflammatory Bowel Diseases (Ulcerative Colitis and Crohn's Disease).Journal of clinical laboratory analysis1 mentions
- 2025Colo-Protective Effects of Pentoxifylline Alone or in Combination With Mesalamine in Colitis Through Sphingosine Kinase 1/Sphingosine 1 Phosphate, and Zonula Occuldin 1 Pathways: New Molecular Approach.Pharmacology research & perspectives1 mentions
- 2025Exploring the dual role of Mangifera indica L. in regulating immune response and pain persistence in inflammatory bowel disease.Pharmacological research1 mentions
- 2025Lactobacillus plantarum with lignin prevents Helicobacter pylori mediated DSS-colitis through improved intestinal integrity and reducing colonic inflammation in C57BL/6J mice.Journal of the science of food and agriculture1 mentions
- 2025Ileal pouch-anal anastomosis in familial adenomatous polyposis and ulcerative colitis with coexisting colorectal cancer: a guideline for treatment.Journal of surgical case reports1 mentions
- 2025The role of gut leakage and immune cell miss-homing on gut dysbiosis-induced lung inflammation in a DSS mice model.PloS one1 mentions
- 2025Acetic acid induced-ulcerative colitis is repressed by morin via modulation of CD3/CD4 mucosal immunity and TLR4/NF-κB/ERK1/2/IL-6 signalling in rats.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association1 mentions
- 2025The Association Between Fast Food Consumption and Inflammatory Bowel Disease: A Case-Control Study and Meta-Analysis.Nutrients1 mentions
- 2025Patient Preferences for Treatment Attributes in Inflammatory Bowel Disease: A Discrete Choice Experiment Among Patients in Five Non-Western Countries.Advances in therapy1 mentions
- 2025Beyond Inflammatory Bowel Disease: Calprotectin as a Marker for Trichobezoar? A Case Report.Case reports in gastroenterology1 mentions
- 2025Innovative pH-responsive alginate-coated rosuvastatin-loaded chitosan nanoparticles: a targeted approach to inhibiting HMGB1-activated RAGE/TLR4-NFκB signaling in colonic inflammation in rats.Frontiers in pharmacology1 mentions
- 2025A Randomized Controlled Pilot Study Evaluating the Safety and Efficacy of Nifuroxazide in Patients with Ulcerative Colitis.Drug design, development and therapy1 mentions
- 2025Long-Term Survival for Locally Advanced Adenosquamous Carcinoma Colon Cancer in Ulcerative Colitis: A Case Report.Case reports in oncology1 mentions
- 2025Biologic therapy utilization trends in inflammatory bowel disease: A narrative review from Saudi Arabia.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2025A systematic review of vedolizumab in treating pediatric ulcerative colitis: efficacy and safety insights.Therapeutic advances in gastroenterology1 mentions
- 2025Efficacy and Safety of 1 L PEG-ASC Preparation for Colonoscopy in Patients with Inflammatory Bowel Diseases: A Multicenter Observational Study.Journal of clinical medicine1 mentions
- 2025Garlic Peel-Derived Phytochemicals Using GC-MS: Antioxidant, Anti-Inflammatory, and Anti-Apoptotic Effects in Ulcerative Colitis Rat Model.Pharmaceuticals (Basel, Switzerland)1 mentions
- 2025Review study of alteration functional activities and networks in ulcerative colitis using resting-state fMRI.Frontiers in neurology1 mentions
- 2025The therapeutic benefits of epigallocatechin gallate in rats with experimentally induced ulcerative colitis are achieved by influencing inflammation and apoptosis.Annals of gastroenterology1 mentions
- 2025Outcomes of Outpatient Advanced Therapy Exposed Patients Hospitalized With Severe Ulcerative Colitis.Crohn's & colitis 3601 mentions
- 2025Nanoencapsulated Syzygium aromaticum oil alleviates acetic acid-induced ulcerative colitis in rats by influencing critical redox, NF-κB/iNOS, and Keap1/Nrf2/HO-1 signaling pathways.Inflammopharmacology1 mentions
- 2025Exploring Anti-TNF Therapy in Relapsing Polychondritis with Co-Existing Ulcerative Colitis: A Case Report and Literature Review.The American journal of case reports1 mentions
- 2025Association of SLC22A4 and TNF-α gene polymorphism with susceptibility to inflammatory bowel disease among patients in the Eastern Province of Saudi Arabia.Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology1 mentions
- 2025Atorvastatin as an immunomodulatory adjunct in ulcerative colitis, beyond lipid lowering to inflammation control: a randomized controlled pilot study.Frontiers in pharmacology1 mentions
- 2025C-Reactive Protein Levels in Patients with Isolated Inflammatory Bowel Disease (Crohn's Disease and Ulcerative Colitis) and Coexisting H. pylori Infection and IBD: A Comparative Study.Inflammatory intestinal diseases1 mentions
- 2025The influence of blood levels of circRNAs and microRNAs on the development of ulcerative colitis.Molecular biology reports1 mentions
- 2025Utilisation and real-world effectiveness of advanced therapies for inflammatory bowel disease in Middle Eastern populations: a systematic review.BMJ open gastroenterology1 mentions
- 2025Therapeutic Modulation of IL-6/STAT-3 and Nitric Oxide by Fenofibrate in Patients With Ulcerative Colitis: A Randomized Controlled Pilot Study.Pharmacotherapy1 mentions
- 2025TNF antagonists withdrawal is not advised in patients with inflammatory bowel disease in remission: a systematic review and meta-analysis of randomized controlled trials.International journal of colorectal disease1 mentions