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Gene profile

C2orf69

HGNC:26799 · SaudiVarKB evidence summary derived from retained literature mentions.

2Gene mentions
2Publications
1Linked variants
1Associated phenotypes

Associated phenotypes

Co-mentioned in C2orf69 publications
PhenotypeIdentifierArticlesMentions
epilepsyHP:000125022

Linked variants

Variants normalized to C2orf69
VariantHGVS / rsIDArticlesMentions
p.Pro107Argp.Pro107Arg11

Population context

Reported in the same publications
Country / regionGroupCohortArticles
Not specified201

Supporting publications

2 records
  1. 2025Homozygous missense variant in C2orf69 causes early-onset neurodegeneration, leukoencephalopathy and autoinflammation.Journal of medical geneticsPubMed ↗
  2. 2021Loss of C2orf69 defines a fatal autoinflammatory syndrome in humans and zebrafish that evokes a glycogen-storage-associated mitochondriopathy.American journal of human geneticsPubMed ↗