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Gene profile

GBE1

HGNC:4180 · SaudiVarKB evidence summary derived from retained literature mentions.

3Gene mentions
3Publications
0Linked variants
1Associated phenotypes

Associated phenotypes

Co-mentioned in GBE1 publications
PhenotypeIdentifierArticlesMentions
epilepsyHP:000125022

Linked variants

Variants normalized to GBE1
VariantHGVS / rsIDArticlesMentions

No normalized variants are linked to this gene.

Population context

Reported in the same publications
Country / regionGroupCohortArticles
Not specified201
Saudi Arabia · Madinah1

Supporting publications

3 records
  1. 2025Homozygous missense variant in C2orf69 causes early-onset neurodegeneration, leukoencephalopathy and autoinflammation.Journal of medical geneticsPubMed ↗
  2. 2024Identification of Novel and Recurrent Variants in BTD, GBE1, AGL and ASL Genes in Families with Metabolic Disorders in Saudi Arabia.Journal of clinical medicinePubMed ↗
  3. 2021Loss of C2orf69 defines a fatal autoinflammatory syndrome in humans and zebrafish that evokes a glycogen-storage-associated mitochondriopathy.American journal of human geneticsPubMed ↗