tuberculosis
SaudiVarKB evidence summary derived from retained literature mentions.
293Phenotype mentions
100Publications
50Associated gene records
48Associated variant records
Associated gene records
Co-mentioned in the same publications| Gene | Identifier / context | Articles | Mentions |
|---|---|---|---|
| NAT2 | HGNC:7646 | 2 | 2 |
| STAT1 | HGNC:11362 | 2 | 2 |
| CYP2B6 | HGNC:2615 | 2 | 2 |
| EGFR | HGNC:3236 | 2 | 2 |
| TLR3 | HGNC:11849 | 2 | 2 |
| STAT4 | HGNC:11365 | 1 | 1 |
| TYK2 | HGNC:12440 | 1 | 1 |
| ZNFX1 | HGNC:29271 | 1 | 1 |
| ABCB1 | HGNC:40 | 1 | 1 |
| CXCL8 | HGNC:6025 | 1 | 1 |
| AKT1 | HGNC:391 | 1 | 1 |
| INS | HGNC:6081 | 1 | 1 |
| CYP3A5 | HGNC:2638 | 1 | 1 |
| JAK2 | HGNC:6192 | 1 | 1 |
| JAK3 | HGNC:6193 | 1 | 1 |
| TLR4 | HGNC:11850 | 1 | 1 |
| ITPA | HGNC:6176 | 1 | 1 |
| MMP1 | HGNC:7155 | 1 | 1 |
| MMP3 | HGNC:7173 | 1 | 1 |
| IL1B | HGNC:5992 | 1 | 1 |
| SLC34A2 | HGNC:11020 | 1 | 1 |
| REL | HGNC:9954 | 1 | 1 |
| SORT1 | HGNC:11186 | 1 | 1 |
| GSTM1 | HGNC:4632 | 1 | 1 |
| HSP90AA1 | HGNC:5253 | 1 | 1 |
| CYBB | HGNC:2578 | 1 | 1 |
| ZMPSTE24 | HGNC:12877 | 1 | 1 |
| IL12B | HGNC:5970 | 1 | 1 |
| IL12A | HGNC:5969 | 1 | 1 |
| NEAT1 | HGNC:30815 | 1 | 1 |
| SPP1 | HGNC:11255 | 1 | 1 |
| CASP1 | HGNC:1499 | 1 | 1 |
| TLR8 | HGNC:15632 | 1 | 1 |
| NRAS | HGNC:7989 | 1 | 1 |
| CXCL5 | HGNC:10642 | 1 | 1 |
| CXCL11 | HGNC:10638 | 1 | 1 |
| CYP2E1 | HGNC:2631 | 1 | 1 |
| TAP2 | HGNC:44 | 1 | 1 |
| ANKRD22 | HGNC:28321 | 1 | 1 |
| HLA-E | HGNC:4962 | 1 | 1 |
| MIF | HGNC:7097 | 1 | 1 |
| CYP2A6 | HGNC:2610 | 1 | 1 |
| MAPK8IP3 | HGNC:6884 | 1 | 1 |
| PLEKHG1 | HGNC:20884 | 1 | 1 |
| CLPB | HGNC:30664 | 1 | 1 |
| DOK4 | HGNC:19868 | 1 | 1 |
| CSF3R | HGNC:2439 | 1 | 1 |
| PRCC | HGNC:9343 | 1 | 1 |
| NR1I2 | HGNC:7968 | 1 | 1 |
| NR1I3 | HGNC:7969 | 1 | 1 |
Associated variant records
Co-mentioned in the same publications| Variant | Identifier / context | Articles | Mentions |
|---|---|---|---|
| L85P | L85P | 2 | 2 |
| rs7975232 | rs7975232 | 1 | 1 |
| rs1544410 | rs1544410 | 1 | 1 |
| rs731236 | rs731236 | 1 | 1 |
| p.S959* | p.S959* | 1 | 1 |
| p.E1606Rfs | p.E1606Rfs | 1 | 1 |
| g.482+82_856-854del | g.482+82_856-854del | 1 | 1 |
| g.315_316insA | g.315_316insA | 1 | 1 |
| rs2228570 | rs2228570 | 1 | 1 |
| rs755622 | rs755622 | 1 | 1 |
| p.Q214R | p.Q214R | 1 | 1 |
| p.M365T | p.M365T | 1 | 1 |
| P62T | P62T | 1 | 1 |
| L120R | L120R | 1 | 1 |
| V130M | V130M | 1 | 1 |
| p.Q36L | p.Q36L | 1 | 1 |
| p.Q317P | p.Q317P | 1 | 1 |
| p.R290X | p.R290X | 1 | 1 |
| rs2430561 | rs2430561 | 1 | 1 |
| S59Y | S59Y | 1 | 1 |
| D86G | D86G | 1 | 1 |
| V180F | V180F | 1 | 1 |
| S104G | S104G | 1 | 1 |
| W68L | W68L | 1 | 1 |
| T87A | T87A | 1 | 1 |
| p.Ala222Arg | p.Ala222Arg | 1 | 1 |
| S531L | S531L | 1 | 1 |
| D516V | D516V | 1 | 1 |
| A46V | A46V | 1 | 1 |
| H71Y | H71Y | 1 | 1 |
| D129N | D129N | 1 | 1 |
| D435Y | D435Y | 1 | 1 |
| H445Y | H445Y | 1 | 1 |
| S450L | S450L | 1 | 1 |
| S450W | S450W | 1 | 1 |
| rs2723176 | rs2723176 | 1 | 1 |
| rs3811046 | rs3811046 | 1 | 1 |
| rs3811047 | rs3811047 | 1 | 1 |
| rs2723186 | rs2723186 | 1 | 1 |
| rs2723187 | rs2723187 | 1 | 1 |
| rs3745274 | rs3745274 | 1 | 1 |
| S94A | S94A | 1 | 1 |
| rs6785049 | rs6785049 | 1 | 1 |
| 516G>T | 516G>T | 1 | 1 |
| A41L | A41L | 1 | 1 |
| C12L | C12L | 1 | 1 |
| A44L | A44L | 1 | 1 |
| A46R | A46R | 1 | 1 |
Associated population records
Co-mentioned in the same publicationsSupporting publications
100 records- 2026Identifying dormancy-associated enzymes in Mycobacterium tuberculosis through a computational pipeline integrating flux balance analysis and metabolic modeling.Molecular diversity1 mentions
- 2026TZ1391: a computationally designed circular mRNA multi-epitope vaccine candidate against Mycobacterium tuberculosis via TLR3 immunomodulation.BMC immunology1 mentions
- 2026Clinical utility of metagenomic next-generation sequencing in diagnosing spinal infections: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society1 mentions
- 2026Machine-Learning-Derived, Mechanistically Informed Transcriptomic Signature to Diagnose Active Tuberculosis and Guide Host-Directed Therapy.Diagnostics (Basel, Switzerland)1 mentions
- 2026Immunological and Hematological Characterisation of Mycobacterium Tuberculosis (M. Tb) Infected Patients.Reviews on recent clinical trials1 mentions
- 2026Mapping the genomic frontier: a comprehensive bibliometric analysis and thematic evolution of whole-genome sequencing for Mycobacterium tuberculosis (1994-2025).World journal of microbiology & biotechnology1 mentions
- 2026Tuberculosis surveillance indicators and chest radiograph phenotype clustering in southwestern Saudi Arabia, 2010-2020.Tropical medicine and health1 mentions
- 2026Deciphering the Molecular Interactions of Tuberculosis and Colorectal Cancer: A Network and RNA-Seq Data Analysis Approach.Anti-cancer agents in medicinal chemistry1 mentions
- 2026Effectiveness of empiric tuberculosis treatment for presumptive smear-negative pulmonary TB among people living with HIV, a systematic narrative review.The Indian journal of tuberculosis1 mentions
- 2026The Shifting Landscape of HIV-Tuberculosis Co-Infection in the MENA Region with a Focus on Saudi Arabia: A Systematic Epidemiological Analysis over Three Decades.Infectious diseases and therapy1 mentions
- 2026An Integrated Review of Conventional and Emerging Diagnostic and Therapeutic Modalities to Reduce the Risk of Surgical Resections in Intestinal Tuberculosis.Diagnostics (Basel, Switzerland)1 mentions
- 2026A Computational Quest for Finding Novel Drug Targets against Mycobacterium tuberculosis.Indian journal of microbiology1 mentions
- 2026Corrigendum to "Genomic landscape of Mycobacterium tuberculosis: Identifying mutation hotspots and stable regions for implications for drug development" [New Microb New Infect 68, (2025) 101674].New microbes and new infections1 mentions
- 2026Disseminated BCGosis in immunocompromised infants: a five-case series in the context of a national BCG vaccination policy change.BMC pediatrics1 mentions
- 2026Structure-Based Virtual Screening of Natural Product-Derived Inhibitors Targeting Rv3806c in the Decaprenylphosphoryl-d-Arabinose Biosynthetic Pathway of Mycobacterium tuberculosis.International journal of molecular sciences1 mentions
- 2026Global, regional, and national burden of tuberculosis and multidrug-resistant tuberculosis by HIV status, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.The Lancet. Infectious diseases1 mentions
- 2025Exploring the genomic potential of Kytococcus schroeteri for antibacterial metabolites against multi-drug resistant Mycobacterium tuberculosis.Journal of infection and public health1 mentions
- 2025Identification and Analysis of Autophagy-Related Genes as Diagnostic Markers and Potential Therapeutic Targets for Tuberculosis Through Bioinformatics.DNA and cell biology1 mentions
- 2025North American clinical practice guidelines for the medical management of hidradenitis suppurativa in special patient populations.Journal of the American Academy of Dermatology1 mentions
- 2025Dynamic Challenges of Active Tuberculosis: Prevalence and Risk Factors of Co-Infection in Clinical and Microbiological Characteristics at King Abdulaziz University Hospital, Jeddah, Saudi Arabia.International journal of general medicine1 mentions
- 2025BCGitis and BCGosis spectrum of imaging findings in immunocompromised pediatric patients.Pediatric radiology1 mentions
- 2025Identification and assessment of hub genes and miRNAs coregulatory associated with immune infiltrations and drug interactions in latent tuberculosis based on MicroarrayData analysis, molecular docking, and dynamic simulation.Biochemistry and biophysics reports1 mentions
- 2025Exploring therapeutic paradigm focusing on genes, proteins, and pathways to combat leprosy and tuberculosis: A network medicine and drug repurposing approach.Journal of infection and public health1 mentions
- 2025Potential role of indole-3-propionic acid in tuberculosis: current perspectives and future prospects.Expert opinion on therapeutic targets1 mentions
- 2025A mathematical framework of HIV and TB co-infection dynamics.Scientific reports1 mentions
- 2025In Silico ADMET Studies, Molecular Docking and Molecular Dynamics Simulation of Thiadiazole Derivatives for the Identification of Putative HsaA Monooxygenase Inhibitors.Current medicinal chemistry1 mentions
- 2025Pharmacokinetics of Tenofovir Diphosphate, Lamivudine Triphosphate and Emtricitabine Triphosphate in Adolescents With HIV Infection With and Without Tuberculosis Coinfection.The Pediatric infectious disease journal1 mentions
- 2025Genotypic drug resistance and transmission clusters of Mycobacterium tuberculosis isolates among Ethiopian returnees from Saudi Arabia.PloS one1 mentions
- 2025A comparative study on TB incidence and HIVTB coinfection using machine learning models on WHO global TB dataset.Scientific reports1 mentions
- 2025The effects of postponing BCG vaccination on the risk of BCG-related complications among patients with severe combined immunodeficiency disease in Saudi Arabia.Frontiers in immunology1 mentions
- 2025Dysregulation and gene polymorphisms of Vitamin D receptor: its implications in lipid metabolic disorders.Molecular biology reports1 mentions
- 2025Endocrine manifestations of lung adenocarcinoma with epidermal growth factor receptor mutation mimicking tuberculosis: A case report and literature review.Qatar medical journal1 mentions
- 2025Global, regional, and national trends in routine childhood vaccination coverage from 1980 to 2023 with forecasts to 2030: a systematic analysis for the Global Burden of Disease Study 2023.Lancet (London, England)1 mentions
- 2025A comprehensive machine learning for high throughput Tuberculosis sequence analysis, functional annotation, and visualization.Scientific reports1 mentions
- 2025Miliary Tuberculosis in an Immunocompetent Patient Presenting with Tuberculous Meningoencephalitis Complicated by Hydrocephalus and Seizures.Journal of global infectious diseases1 mentions
- 2025MetE: a promising protective antigen for tuberculosis vaccine development.Frontiers in immunology1 mentions
- 2025Impact of Genetic Polymorphisms on the Efficacy and Safety of Isoniazid in Saudi Tuberculosis Patients.International journal of genomics1 mentions
- 2025Advancing the fight against tuberculosis: integrating innovation and public health in diagnosis, treatment, vaccine development, and implementation science.Frontiers in medicine1 mentions
- 2025Mapping the immunological research landscape of tuberculosis: A bibliometric review of global trends and clinical themes (2016-2025).Journal of infection and public health1 mentions
- 2025Burden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.Lancet (London, England)1 mentions
- 2025Global burden of 292 causes of death in 204 countries and territories and 660 subnational locations, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.Lancet (London, England)1 mentions
- 2025Emergence of novel sublineages of Mycobacterium tuberculosis in Pakistan.International journal of medical microbiology : IJMM1 mentions
- 2025IFN-γ-Driven macrophage responses in the immunity to Mycobacterium tuberculosis and Mycobacterium leprae.Frontiers in cellular and infection microbiology1 mentions
- 2025Genomic landscape of Mycobacterium tuberculosis: Identifying mutation hotspots and stable regions for implications for drug development.New microbes and new infections1 mentions
- 2025AI-powered risk prediction of tuberculosis reactivation in latently infected individuals.The Indian journal of tuberculosis1 mentions
- 2025Incidence, risk factors and outcomes of BCGosis following BCG vaccination in infants: a systematic review and meta-analyses.Frontiers in immunology1 mentions
- 2024The use of a tumor necrosis factor inhibitor-adalimumab-in the management of arthritis in an adolescent with HIV: A case report.International journal of rheumatic diseases1 mentions
- 2024Free energy landscape and thermodynamics properties of novel mutations in PncA of pyrazinamide resistance isolates of Mycobacterium tuberculosis.Journal of biomolecular structure & dynamics1 mentions
- 2024Modulation of lncRNA NEAT1 overturns the macrophages based immune response in M. tuberculosis infected patients via miR-373 regulation.Journal of applied genetics1 mentions
- 2024Integrated Network Pharmacology Approach to Evaluate Bioactive Phytochemicals of Acalypha indica and Their Mechanistic Actions to Suppress Target Genes of Tuberculosis.ACS omega1 mentions
- 2024Identification of new anti-mycobacterial agents based on quinoline-isatin hybrids targeting enoyl acyl carrier protein reductase (InhA).Bioorganic chemistry1 mentions
- 2024Tuberculosis in Sudan: systematic review and meta analysis.BMC pulmonary medicine1 mentions
- 2024Consanguineous marriages increase the incidence of recurrent tuberculosis: Evidence from whole exome sequencing.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases1 mentions
- 2024QSPR analysis of distance-based structural indices for drug compounds in tuberculosis treatment.Heliyon1 mentions
- 2024The oral microbiome of newly diagnosed tuberculosis patients; a pilot study.Genomics1 mentions
- 2024Identification of Mycobacterium tuberculosis transcriptional repressor EthR inhibitors: Shape-based search and machine learning studies.Heliyon1 mentions
- 2024Prevalence of co-infection of human immunodeficiency virus in diagnosed tuberculosis cases: Meta-analysis.International journal of health sciences1 mentions
- 2024Tuberculous Otitis Media With Cerebral Venous Thrombosis: A Rare and Challenging Diagnostic Case.Cureus1 mentions
- 2024Activity against Mycobacterium tuberculosis of a new class of spirooxindolopyrrolidine embedded chromanone hybrid heterocycles.RSC advances1 mentions
- 2024In silico identification of phytochemical inhibitors for multidrug-resistant tuberculosis based on novel pharmacophore generation and molecular dynamics simulation studies.BMC chemistry1 mentions
- 2024The prevalence of pneumothorax in human immunodeficiency virus patients. A single center study.Saudi medical journal1 mentions
- 2024An HLA-E-targeted TCR bispecific molecule redirects T cell immunity against Mycobacterium tuberculosis.Proceedings of the National Academy of Sciences of the United States of America1 mentions
- 2024The risk of tuberculosis infection in Saudi patients receiving adalimumab, etanercept, and tocilizumab therapy.Journal of infection and public health1 mentions
- 2024Tuberculoma mimicking en-plaque meningioma in a 45-year-old male: A case report.Surgical neurology international1 mentions
- 2024Fatal Nocardia paucivorans Lower Respiratory Tract Infection in a Tuberculosis Suspect Who Worked as Gold Miner.International journal of mycobacteriology1 mentions
- 2024Insights into the Effects of Ligand Binding on Leucyl-tRNA Synthetase Inhibitors for Tuberculosis: In Silico Analysis and Isothermal Titration Calorimetry Validation.Biomolecules1 mentions
- 2024Impact of bedaquiline regimen on the treatment success rates of multidrug-resistant tuberculosis patients in Egypt.Scientific reports1 mentions
- 2024WHO global research priorities for antimicrobial resistance in human health.The Lancet. Microbe1 mentions
- 2024Identification of 2-(N-aryl-1,2,3-triazol-4-yl) quinoline derivatives as antitubercular agents endowed with InhA inhibitory activity.Frontiers in chemistry1 mentions
- 2024Resistome Signature and Antibiotic Resistance Mechanisms in Rhizospheric Soil Bacteriomes of Mecca Region, Saudi Arabia: Insights into Impact on Human Health.Life (Basel, Switzerland)1 mentions
- 2024Identification of echinoderm metabolites as potential inhibitors targeting wild-type and mutant forms of Escherichia coli RNA polymerase (RpoB) for tuberculosis treatment.PloS one1 mentions
- 2024Regional and National Trends in Tuberculosis Research in South Asian Association for Regional Cooperation Countries: Post-COVID-19 Pandemic Machine Learning Factorial Analysis.International journal of mycobacteriology1 mentions
- 2024Left Middle Phalanx Tuberculous Dactylitis Masquerading as a Tumor: First Case Report in Saudi Arabia.Plastic and reconstructive surgery. Global open1 mentions
- 2024Benzenesulfonohydrazide-tethered non-fused and fused heterocycles as potential anti-mycobacterial agents targeting enoyl acyl carrier protein reductase (InhA) with antibiofilm activity.RSC advances1 mentions
- 2024Cachexia in tuberculosis in South-East Asian and African regions: knowledge gaps and untapped opportunities.Annals of medicine and surgery (2012)1 mentions
- 2024Magnitude and Determinants of Latent Tuberculosis Among Inmates of Saudi Correctional Facilities: A Cross-Sectional Study.International journal of general medicine1 mentions
- 2024Left hand abscess as a paradoxical reaction during treatment of disseminated tuberculosis in immunocompetent patient: case report and review of literature.BMC infectious diseases1 mentions
- 2024Comprehensive pan-genome analysis of Mycobacterium marinum: insights into genomic diversity, evolution, and pathogenicity.Scientific reports1 mentions
- 2024Substrate-Induced Structural Dynamics and Evolutionary Linkage of Siderophore-Iron ABC Transporters of Mycobacterium tuberculosis.Medicina (Kaunas, Lithuania)1 mentions
- 2023Diversity and novel mutations in membrane transporters of Mycobacterium tuberculosis.Briefings in functional genomics1 mentions
- 2023Deciphering the mechanism of resistance by novel double mutations in pncA in Mycobacterium tuberculosis using protein structural graphs (PSG) and structural bioinformatic approaches.Computers in biology and medicine1 mentions
- 2023Study of drug interaction, mutant frequency and mutant prevention concentration of DFMBT against Mycobacterium tuberculosis H37RV.Microbial pathogenesis1 mentions
- 2023Classical fever of unknown origin in 21 countries with different economic development: an international ID-IRI study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology1 mentions
- 2023Multimodality imaging workup of classical Hodgkin lymphoma in an 8-month-old child.Radiology case reports1 mentions
- 2023Clinico-demographic and survival profile of people living with HIV on antiretroviral treatment.Frontiers in public health1 mentions
- 2023Primary tuberculous otomastoiditis complicated with Bezold's, postauricular, and subdural abscesses: a case report and review of the literature.Journal of surgical case reports1 mentions
- 2023Isoflavonoid and Furanochromone Natural Products as Potential DNA Gyrase Inhibitors: Computational, Spectral, and Antimycobacterial Studies.ACS omega1 mentions
- 2023Basidiobolomycosis Mimicking Fistulizing Crohn's Disease: A Case Report From Saudi Arabia.Cureus1 mentions
- 2023Clinicopathological profile of peritoneal tuberculosis and a new scoring model for predicting mortality: an international ID-IRI study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology1 mentions
- 2023Highlights on the Development, Related Patents, and Prospects of Lenacapavir: The First-in-Class HIV-1 Capsid Inhibitor for the Treatment of Multi-Drug-Resistant HIV-1 Infection.Medicina (Kaunas, Lithuania)1 mentions
- 2023Novel mutations in genes of the IL-12/IFN-γ axis cause susceptibility to tuberculosis.Journal of infection and public health1 mentions
- 2023The effect of anti-tuberculosis drug pharmacokinetics on QTc prolongation.International journal of antimicrobial agents1 mentions
- 2023Deciphering the emerging role of phytocompounds: Implications in the management of drug-resistant tuberculosis and ATDs-induced hepatic damage.Journal of infection and public health1 mentions
- 2023Subtractive panning for the isolation of monoclonal PEPITEM peptide antibody by phage display.Scientific reports1 mentions
- 2023Exploring recombinant secretory proteins from Mycobacterium tuberculosis to develop a serological platform for tuberculosis diagnosis.International journal of biological macromolecules1 mentions
- 2023Evaluation of Xpert MTB/RIF Ultra for the Diagnosis of Extrapulmonary Tuberculosis: A Retrospective Analysis in Saudi Arabia.Journal of epidemiology and global health1 mentions
- 2023Overcoming Mycobacterium tuberculosis Drug Resistance: Novel Medications and Repositioning Strategies.ACS omega1 mentions
- 2023The clinical impact of rifampicin-based anti-TB therapy and tenofovir alafenamide-containing ARV regimen drug Interaction in people living with HIV: Case series report.Journal of infection and public health1 mentions
- 2023Evaluating the Sensitivity of Different Molecular Techniques for Detecting Mycobacterium tuberculosis Complex in Patients with Pulmonary Infection.Polish journal of microbiology1 mentions
- 2023Correlation of anti-TNF-a biological therapy with periodontal conditions and osteonecrosis in autoimmune patients: A systematic review.The Saudi dental journal1 mentions