SARS
SaudiVarKB evidence summary derived from retained literature mentions.
273Phenotype mentions
100Publications
50Associated gene records
50Associated variant records
Associated gene records
Co-mentioned in the same publications| Gene | Identifier / context | Articles | Mentions |
|---|---|---|---|
| ACE2 | HGNC:13557 | 27 | 27 |
| TLR4 | HGNC:11850 | 3 | 3 |
| CRP | HGNC:2367 | 2 | 2 |
| ABO | HGNC:79 | 2 | 2 |
| IRF7 | HGNC:6122 | 2 | 2 |
| CFH | HGNC:4883 | 2 | 2 |
| TLR8 | HGNC:15632 | 2 | 2 |
| TBK1 | HGNC:11584 | 2 | 2 |
| IFNAR2 | HGNC:5433 | 2 | 2 |
| TMPRSS2 | HGNC:11876 | 2 | 2 |
| NLRP3 | HGNC:16400 | 1 | 1 |
| CDKN1A | HGNC:1784 | 1 | 1 |
| APOE | HGNC:613 | 1 | 1 |
| HBB | HGNC:4827 | 1 | 1 |
| STAT1 | HGNC:11362 | 1 | 1 |
| MTHFR | HGNC:7436 | 1 | 1 |
| CBS | HGNC:1550 | 1 | 1 |
| LDLR | HGNC:6547 | 1 | 1 |
| ALDH1A1 | HGNC:402 | 1 | 1 |
| TP53 | HGNC:11998 | 1 | 1 |
| TF | HGNC:11740 | 1 | 1 |
| ACE | HGNC:2707 | 1 | 1 |
| CPS1 | HGNC:2323 | 1 | 1 |
| RAD51 | HGNC:9817 | 1 | 1 |
| PCSK9 | HGNC:20001 | 1 | 1 |
| LZTFL1 | HGNC:6741 | 1 | 1 |
| HFE | HGNC:4886 | 1 | 1 |
| BCL2L1 | HGNC:992 | 1 | 1 |
| HLA-A | HGNC:4931 | 1 | 1 |
| CUL2 | HGNC:2552 | 1 | 1 |
| ELOB | HGNC:11619 | 1 | 1 |
| ELOC | HGNC:11617 | 1 | 1 |
| MAP7D1 | HGNC:25514 | 1 | 1 |
| PPT1 | HGNC:9325 | 1 | 1 |
| RBX1 | HGNC:9928 | 1 | 1 |
| THTPA | HGNC:18987 | 1 | 1 |
| TIMM8B | HGNC:11818 | 1 | 1 |
| ZYG11B | HGNC:25820 | 1 | 1 |
| F5 | HGNC:3542 | 1 | 1 |
| FGG | HGNC:3694 | 1 | 1 |
| CDH23 | HGNC:13733 | 1 | 1 |
| TLR3 | HGNC:11849 | 1 | 1 |
| CREBBP | HGNC:2348 | 1 | 1 |
| EP300 | HGNC:3373 | 1 | 1 |
| IFNAR1 | HGNC:5432 | 1 | 1 |
| CLC | HGNC:2014 | 1 | 1 |
| FGA | HGNC:3661 | 1 | 1 |
| HMGB1 | HGNC:4983 | 1 | 1 |
| KPNA2 | HGNC:6395 | 1 | 1 |
| TLR2 | HGNC:11848 | 1 | 1 |
Associated variant records
Co-mentioned in the same publications| Variant | Identifier / context | Articles | Mentions |
|---|---|---|---|
| D614G | D614G | 4 | 4 |
| L452R | L452R | 3 | 3 |
| E484K | E484K | 2 | 2 |
| N501Y | N501Y | 2 | 2 |
| H63D | H63D | 1 | 1 |
| p.F8S | p.F8S | 1 | 1 |
| rs16944 | rs16944 | 1 | 1 |
| K417N | K417N | 1 | 1 |
| rs1143634 | rs1143634 | 1 | 1 |
| rs12083537 | rs12083537 | 1 | 1 |
| rs1042522 | rs1042522 | 1 | 1 |
| p.His63Asp | p.His63Asp | 1 | 1 |
| p.Glu7Val | p.Glu7Val | 1 | 1 |
| Q57H | Q57H | 1 | 1 |
| F35G | F35G | 1 | 1 |
| L37F | L37F | 1 | 1 |
| L125F | L125F | 1 | 1 |
| I162T | I162T | 1 | 1 |
| V24A | V24A | 1 | 1 |
| W27L | W27L | 1 | 1 |
| I33T | I33T | 1 | 1 |
| A242V | A242V | 1 | 1 |
| R708W | R708W | 1 | 1 |
| G405E | G405E | 1 | 1 |
| D292N | D292N | 1 | 1 |
| Y633C | Y633C | 1 | 1 |
| F308L | F308L | 1 | 1 |
| P323L | P323L | 1 | 1 |
| rs9792388 | rs9792388 | 1 | 1 |
| rs3025892 | rs3025892 | 1 | 1 |
| S477N | S477N | 1 | 1 |
| N969K | N969K | 1 | 1 |
| S884F | S884F | 1 | 1 |
| G446V | G446V | 1 | 1 |
| R102S | R102S | 1 | 1 |
| G181V | G181V | 1 | 1 |
| A97V | A97V | 1 | 1 |
| P323I | P323I | 1 | 1 |
| Y606C | Y606C | 1 | 1 |
| N439K | N439K | 1 | 1 |
| rs4240157 | rs4240157 | 1 | 1 |
| rs4343 | rs4343 | 1 | 1 |
| rs11614913 | rs11614913 | 1 | 1 |
| E484Q | E484Q | 1 | 1 |
| L452R | L452R | 1 | 1 |
| T478K | T478K | 1 | 1 |
| N501Y | N501Y | 1 | 1 |
| rs5744080 | rs5744080 | 1 | 1 |
| rs2159377 | rs2159377 | 1 | 1 |
| R24C | R24C | 1 | 1 |
Associated population records
Co-mentioned in the same publicationsSupporting publications
100 records- 2026Exploring natural compounds and synthetic derivatives as potential inhibitors of SARS-CoV-2 PLpro: a computational approach with enzyme inhibition and cytotoxicity assessment.Journal of biomolecular structure & dynamics1 mentions
- 2026Protracted SARS-CoV-2 Infection in B-cell Depleted Patients: Immunologic and Viral Characteristics and Response to Dual and Extended Antiviral Therapy.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America1 mentions
- 2026IFNAR2 p.F8S Variant Associates with Severe COVID-19 and Adaptive Immune Cell Activation Modulation.International journal of molecular sciences1 mentions
- 2026Fundamental concepts of convergent (parallel) evolution in human-pathogenic viruses and their implications for global health.Virology1 mentions
- 2026Clinical Outcomes with the Use of Dipeptidyl Peptidase-4 (DPP-4) Inhibitor Among Patients with Diabetes Mellitus and COVID-19: A Systematic Review of Observational Studies.Journal of clinical medicine1 mentions
- 2026Vaccine effectiveness across the Omicron evolutionary spectrum (BA.2, BA.5, XBB, JN.1, KP.3): a systematic review of studies published 2022-2025.BMC infectious diseases1 mentions
- 2026Targeting SARS-CoV-2 main protease (3CLpro) with Paeonia-derived phytochemicals.In silico pharmacology1 mentions
- 2026Biochemical insights and microRNA profiling via next-generation sequencing in moderate and severe COVID-19 cases.Clinics (Sao Paulo, Brazil)1 mentions
- 2026Gold nanoparticles as dual-action antiviral agents: disruption of SARS-CoV-2 viral envelopes and RNA integrity.Scientific reports1 mentions
- 2025Molecular dynamic analyses of the interaction of SARS-CoV-1 or 2 variants with various angiotensin-converting enzyme-2 species.Journal of biomolecular structure & dynamics1 mentions
- 2025Clinical and epidemiological characteristics of respiratory syncytial virus, SARS-CoV-2 and influenza paediatric viral respiratory infections in southwest Saudi Arabia.Annals of medicine1 mentions
- 2025Uncovering Antiviral Potential of Cistus Ladanifer Extracts Against Herpes Simplex Virus 1 and Severe Acute Respiratory Syndrome Coronavirus 2 by In Vitro and In Silico Analysis.Chemistry & biodiversity1 mentions
- 2025In-Utero Maternal-to-Fetal Transmission of COVID-19: An Immunological and Virological Study in the Eastern Province of Saudi Arabia.Infection and drug resistance1 mentions
- 2025Silaproline-bearing nirmatrelvir derivatives are potent inhibitors of the SARS-CoV-2 main protease highlighting the value of silicon-derivatives in structure-activity-relationship studies.European journal of medicinal chemistry1 mentions
- 2025Innate immunity, therapeutic targets and monoclonal antibodies in SARS-CoV-2 infection.PeerJ1 mentions
- 2025First-in-class inhibitors of Nsp15 endoribonuclease of SARS-CoV-2: Modeling, synthesis, and enzymatic assay of thiazolidinedione and rhodanine analogs.The Journal of biological chemistry1 mentions
- 2025Immune transcriptomic analysis on COVID-19 patients with varying clinical presentations identifies severity markers.Scientific reports1 mentions
- 2025Fatty Acids and Inflammatory Protein Biomarkers From Coronavirus Disease 2019 Patients.Immunity, inflammation and disease1 mentions
- 2025Impact of COVID-19 vaccination on cancer patients: safety, efficacy, and long-term effects.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer1 mentions
- 2025New Neonatal and Prenatal Approach to Home Therapy with Amoxicillin, Rifaximin, and Anti-Inflammatory Drugs for Pregnant Women with COVID-19 Infections-Monitoring of Fetal Growth as a Prognostic Factor: A Triple Case Series (N.A.T.H.A.N.).Biomedicines1 mentions
- 2025Multisystem inflammatory syndrome in children (MIS-C) presenting with valvulitis, myocarditis, and QTc prolongation: A case report from Saudi Arabia.Medicine1 mentions
- 2025Immuno-epigenetic paradigms in coronavirus infection.Frontiers in immunology1 mentions
- 2025An exploratory binding study of molnupiravir efficacy against emerging Omicron SARS-CoV-2 variants.Scientific reports1 mentions
- 2025Cross-national disparities in healthcare workers' perceptions: Examining fear of infection and confidence in the received COVID-19 vaccines amid emerging variants.PloS one1 mentions
- 2025COVID-19 vaccine-induced autoimmune hyperthyroidism: Graves' disease.Frontiers in immunology1 mentions
- 2025Potential relationships between circulating gene expression of ACE2, TLR4, and IL-17 and disease severity and outcome of hospitalized patients with COVID-19.Journal of Zhejiang University. Science. B1 mentions
- 2024Structural basis for the mechanism of interaction of SARS-CoV-2 B.1.640.2 variant RBD with the host receptors hACE2 and GRP78.Journal of biomolecular structure & dynamics1 mentions
- 2024Impact of Respiratory Viruses and SARS-CoV-2 on Febrile Seizures in Saudi Children: Insights into Etiologies, Gender, and Familial Associations.Medical science monitor : international medical journal of experimental and clinical research1 mentions
- 2024SARS-CoV-2 NSP14 governs mutational instability and assists in making new SARS-CoV-2 variants.Computers in biology and medicine1 mentions
- 2024Molecular docking as a tool for the discovery of novel insight about the role of acid sphingomyelinase inhibitors in SARS- CoV-2 infectivity.BMC public health1 mentions
- 2024ACE2-Fc and DPP4-Fc decoy receptors against SARS-CoV-2 and MERS-CoV variants: a quick therapeutic option for current and future coronaviruses outbreaks.Antibody therapeutics1 mentions
- 2024Fusing Peptide Epitopes for Advanced Multiplex Serological Testing for SARS-CoV-2 Antibody Detection.ACS bio & med chem Au1 mentions
- 2024Utilizing sinapic acid as an inhibitory antiviral agent against MERS-CoV PLpro.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society1 mentions
- 2024Potential use of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibition and prevention method in viral infection.Microbial cell factories1 mentions
- 2024The global impact of SARS-CoV-2 variant BA.2.86: a comprehensive analysis with the latest developments and transmission trends - an epidemiological study.European review for medical and pharmacological sciences1 mentions
- 2024Assessment and classification of COVID-19 DNA sequence using pairwise features concatenation from multi-transformer and deep features with machine learning models.SLAS technology1 mentions
- 2024Pathogenesis of COVID19 and the applications of US FDA-approved repurposed antiviral drugs to combat SARS-CoV-2 in Saudi Arabia: A recent update by review of literature.Saudi journal of biological sciences1 mentions
- 2024Whole-Exome Sequencing Detecting a Recurrent Pathogenic Mutation, HFE p.His63Asp (H63D) in COVID-19 Patients and Its Effect on Mortality.Discovery medicine1 mentions
- 2024Circulation of Non-Middle East Respiratory Syndrome (MERS) Coronaviruses in Imported Camels in Saudi Arabia.Cureus1 mentions
- 2024Assessing the impact of severe acute respiratory syndrome coronavirus 2 infection on hematological parameters.Transactions of the Royal Society of Tropical Medicine and Hygiene1 mentions
- 2024Genetic risk factors for COVID-19 and influenza are largely distinct.Nature genetics1 mentions
- 2024Spectrum of respiratory viruses identified from SARS-CoV-2-negative human respiratory tract specimens in Watansoppeng, Indonesia.Access microbiology1 mentions
- 2024A review of the role of graphene-based nanomaterials in tackling challenges posed by the COVID-19 pandemic.Microbial pathogenesis1 mentions
- 2024Interleukin-1 Beta rs16944 and rs1143634 and Interleukin-6 Receptor rs12083537 Single Nucleotide Polymorphisms as Potential Predictors of COVID-19 Severity.Pathogens (Basel, Switzerland)1 mentions
- 2024Inactivation of Pseudovirus Expressing the D614G Spike Protein Mutation using Nitric Oxide-Plasma Activated Water.Advanced science (Weinheim, Baden-Wurttemberg, Germany)1 mentions
- 2024Vesicular Stomatitis Virus as a Platform for Protease Activity Measurements.Current protocols1 mentions
- 2024Exploring advanced genomic and immunoinformatics techniques for identifying drug and vaccine targets against SARS-CoV-2.Journal, genetic engineering & biotechnology1 mentions
- 2023The relevant information about the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using the five-question approach (when, where, what, why, and how) and its impact on the environment.Environmental science and pollution research international1 mentions
- 2023Reporting dinaciclib and theodrenaline as a multitargeted inhibitor against SARS-CoV-2: an in-silico study.Journal of biomolecular structure & dynamics1 mentions
- 2023Mechanistic Insight and Possible Mechanism of Seizure in Covid-19: The Nuances and Focal Points.CNS & neurological disorders drug targets1 mentions
- 2023Monoclonal antibody designed for SARS-nCoV-2 spike protein of receptor binding domain on antigenic targeted epitopes for inhibition to prevent viral entry.Molecular diversity1 mentions
- 2023Unveiling the multitargeted potential of N-(4-Aminobutanoyl)-S-(4-methoxybenzyl)-L-cysteinylglycine (NSL-CG) against SARS CoV-2: a virtual screening and molecular dynamics simulation study.Journal of biomolecular structure & dynamics1 mentions
- 2023PheroxyPyrabenz and Carbopyrropyridin against major proteins of SARS CoV-2: a comprehensive in-silico molecular docking and dynamics simulation studies.Journal of biomolecular structure & dynamics1 mentions
- 2023Global emerging Omicron variant of SARS-CoV-2: Impacts, challenges and strategies.Journal of infection and public health1 mentions
- 2023Analysis of SARS-CoV-2 genomic surveillance data during the Delta and Omicron waves at a Saudi tertiary referral hospital.Journal of infection and public health1 mentions
- 2023Dysrhythmias associated with COVID-19: Review and management considerations.The American journal of emergency medicine1 mentions
- 2023Advanced Plasmonic Nanoparticle-Based Techniques for the Prevention, Detection, and Treatment of Current COVID-19.Plasmonics (Norwell, Mass.)1 mentions
- 2023COVID-19: A state of art on immunological responses, mutations, and treatment modalities in riposte.Journal of infection and public health1 mentions
- 2023Safety, Tolerability and Pharmacokinetics of Half-Life Extended Severe Acute Respiratory Syndrome Coronavirus 2 Neutralizing Monoclonal Antibodies AZD7442 (Tixagevimab-Cilgavimab) in Healthy Adults.The Journal of infectious diseases1 mentions
- 2023Assessment of the Prevalence and Incidence of COVID-19 in Saudi Arabia.Journal of multidisciplinary healthcare1 mentions
- 2023Whale optimization with random contraction and Rosenbrock method for COVID-19 disease prediction.Biomedical signal processing and control1 mentions
- 2023In silico prediction of potential inhibitors for SARS-CoV-2 Omicron variant using molecular docking and dynamics simulation-based drug repurposing.Journal of molecular modeling1 mentions
- 2023Molecular evolutionary model based on phylogenetic and mutation analysis of SARS-CoV-2 spike protein sequences from Asian countries: A phylogenomic approach.Informatics in medicine unlocked1 mentions
- 2023Artificial Intelligence: A Next-Level Approach in Confronting the COVID-19 Pandemic.Healthcare (Basel, Switzerland)1 mentions
- 2023The potential role of SARS-CoV-2 infection in acute coronary syndrome and type 2 myocardial infarction (T2MI): Intertwining spread.Immunity, inflammation and disease1 mentions
- 2023SARS-CoV-2 Detection and COVID-19 Diagnosis: A Bird's Eye View.Reviews on recent clinical trials1 mentions
- 2023SARS-CoV-2 Outbreak Investigation Using Contact Tracing and Whole-Genome Sequencing in an Ontario Tertiary Care Hospital.Microbiology spectrum1 mentions
- 2023The potential role of scavenger receptor B type I (SR-BI) in SARS-CoV-2 infection.Immunity, inflammation and disease1 mentions
- 2023CRISPR-Cas13a-powered electrochemical biosensor for the detection of the L452R mutation in clinical samples of SARS-CoV-2 variants.Journal of nanobiotechnology1 mentions
- 2023Clinical features of Omicron variant infection in 445 patients with coronavirus 19 disease.Annals of Saudi medicine1 mentions
- 2023Discovering common pathogenic processes between COVID-19 and HFRS by integrating RNA-seq differential expression analysis with machine learning.Frontiers in microbiology1 mentions
- 2023The effects of prolactin on the immune system, its relationship with the severity of COVID-19, and its potential immunomodulatory therapeutic effect.Cytokine1 mentions
- 2023Genome-wide epistasis study highlights genetic interactions influencing severity of COVID-19.European journal of epidemiology1 mentions
- 2023Viruses and autism: A Bi-mutual cause and effect.World journal of virology1 mentions
- 2023T cell receptor β repertoires in patients with COVID-19 reveal disease severity signatures.Frontiers in immunology1 mentions
- 2023Preoperative universal screening of coronavirus disease 2019 during Omicron outbreak in patients undergoing ophthalmic surgeries: Experience from a tertiary eye care center in Saudi Arabia.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society1 mentions
- 2023The Effect of COVID-19 Vaccines on Hospital Admission and Severity of Symptoms Among COVID-19 Patients in Saudi Arabia, 2021.Cureus1 mentions
- 2023Coronavirus and co-infections: A Saudi Arabian perspective.Saudi journal of biological sciences1 mentions
- 2023Early and Sensitive Detection of Pathogens for Public Health and Biosafety: An Example of Surveillance and Genotyping of SARS-CoV-2 in Sewage Water by Cas12a-Facilitated Portable Plasmonic Biosensor.Research (Washington, D.C.)1 mentions
- 2023Natural Killer Cells in SARS-CoV-2-Vaccinated Subjects with Increased Effector Cytotoxic CD56dim Cells and Memory-Like CD57+NKG2C+CD56dim Cells.Frontiers in bioscience (Landmark edition)1 mentions
- 2023Repurposing the oncolytic virus VSV∆51M as a COVID-19 vaccine.Frontiers in bioengineering and biotechnology1 mentions
- 2023SARS-CoV-2 infections and MIS-C among children: A narrative review.Medicine1 mentions
- 2023Severity of SARS-CoV-2 infection in children with inborn errors of immunity (primary immunodeficiencies): a systematic review.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology1 mentions
- 2023Development of Rapid Aptamer-Based Screening Assay for the Detection of Covid-19 Variants.ACS omega1 mentions
- 2023Design and Assessment of a Novel In Silico Approach for Developing a Next-Generation Multi-Epitope Universal Vaccine Targeting Coronaviruses.Microorganisms1 mentions
- 2023Insights on Covid-19 with superimposed pulmonary histoplasmosis: The possible nexus.Immunity, inflammation and disease1 mentions
- 2023Intrinsic factors behind long-COVID: II. SARS-CoV-2, extracellular vesicles, and neurological disorders.Journal of cellular biochemistry1 mentions
- 2023Incompetent memory immune response in severe COVID-19 patients under treatment.Heliyon1 mentions
- 2023Omicron new variant BA.2.86 (Pirola): Epidemiological, biological, and clinical characteristics - a global data-based analysis.European review for medical and pharmacological sciences1 mentions
- 2023Evaluation of Potential Peptide-Based Inhibitors against SARS-CoV-2 and Variants of Concern.BioMed research international1 mentions
- 2023Blood coagulation, risk factors and associated complications in COVID-19 patients in Saudi Arabia: A retrospective cohort study.Medicine1 mentions
- 2023Effectiveness of COVID-19 vaccines against ICU admission during Omicron surge in Saudi Arabia: a nationwide retrospective cohort study.BMC infectious diseases1 mentions
- 2023Efficacy of Oxford-AstraZeneca (ChAdOx1 CoV-19) vaccine against Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) cases, hospital admissions, type of variants, and deaths.European review for medical and pharmacological sciences1 mentions
- 2023Non-synonymous Single Nucleotide Polymorphisms in Human ACE2 Gene May Affect the Infectivity of SARS-CoV-2 Omicron Subvariants.Current pharmaceutical design1 mentions
- 2023Navigating Vaccine Uncertainty: Anxiety and Fourth Dose Hesitancy Among Saudi Adults.Cureus1 mentions
- 2023Mutational analysis of SARS-CoV-2 ORF6-KPNA2 binding interface and identification of potent small molecule inhibitors to recuse the host immune system.Frontiers in immunology1 mentions
- 2023Elucidating the binding mechanism of SARS-CoV-2 NSP6-TBK1 and structure-based designing of phytocompounds inhibitors for instigating the host immune response.Frontiers in chemistry1 mentions
- 2022Effect of mutation and vaccination on spread, severity, and mortality of COVID-19 disease.Journal of medical virology1 mentions
- 2022Analyzing the effect of mutations in SARS-CoV2 papain-like protease from Saudi isolates on protein structure and drug-protein binding: Molecular modelling and dynamics studies.Saudi journal of biological sciences1 mentions
- 2022Periodically aperiodic pattern of SARS-CoV-2 mutations underpins the uncertainty of its origin and evolution.Environmental research1 mentions