TF
HGNC:11740 · 28 retained evidence mentions
Source-grounded findings
Supporting evidence
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| gene | TF | “Among the key transcription factor (TF) families involved in plant stress responses; the nuclear factor-Y (NF-Y) family plays a pivotal role in modulating gene expression under environmental stresses.” | 0.98 | hgnc_dict_v1 |
| gene | TF | “Moreover, SNP + MT lessens metal-induced toxicity by decreasing Cd uptake, translocation (TF) and bioconcentration (BCF) factors.” | 0.98 | hgnc_dict_v1 |
| gene | TF | “Additionally, related gene ontology concepts (e.g. sequence-specific DNA binding and TF activity) connected to DEGs in HD were identified using gene set enrichment analysis (GSEA).” | 0.98 | hgnc_dict_v1 |
| gene | TF | “As observed from FFL centrality measures, the highest-order subnetwork motif comprised one TF (SOX7), one miRNA (miR-484), and one mRNA (SPARC) in the case of GSE28829.” | 0.98 | hgnc_dict_v1 |
| gene | TF | “Here, we have used a single mRNA detection method in live-cells to comprehend the ON/OFF mechanism of the first transcriptional (TF) and consecutive events (TC) controlled by lactose promoters, Plac and Plac/ara1.” | 0.98 | hgnc_dict_v1 |
| gene | TF | “The MYB transcription factor (TF) are among the largest gene families of plants being responsible for several biological processes.” | 0.98 | hgnc_dict_v1 |
| gene | TF | “This work additionally identified the connection of TF genes and miRNAs with common DEGs, as well as TF activity.” | 0.98 | hgnc_dict_v1 |
| gene | TF | “There are contemplating evidences that demonstrate the role of transcription factors (TF) in sustaining the neoplastic stem cell's pluripotency and plasticity alongside the miRNA in regulation of crucial genes involved in the transformation of normal oral mucosa to malignancy.” | 0.98 | hgnc_dict_v1 |
| gene | TF | “Among these genes, one TF belongs to the zinc finger protein CONSTANS family and proved via qPCR to drive expression of a gene encoding a speculative TF namely zinc transporter 3-like and two other stress related genes encoding tryptophan synthase alpha chain and asparagine synthetase.” | 0.98 | hgnc_dict_v1 |
| gene | TF | “However, a single TF binding site was lost at g.202A > T due to SNP3.” | 0.98 | hgnc_dict_v1 |
| gene | TF | “Furthermore, screening of the LF promoter sequence explored the gain of four TF binding sites at locus g.98T˃C and three TF binding sites at g.346A˃G.” | 0.98 | hgnc_dict_v1 |
| gene | TF | “Moreover, in SNP1 loss of 3 transcription factors (TF) binding sites occurred, SNP2 caused loss of two TFs binding sites, and SNP3 caused loss of a single TF binding site.” | 0.98 | hgnc_dict_v1 |
| gene | TF | “TF and TCF4 gene polymorphisms are linked to autism spectrum disorder: a case-control study.” | 0.98 | hgnc_dict_v1 |
| gene | TF | “Identification of TF-miRNA association network reveals the interconnection between TF genes and miRNAs, which may be effective to reveal the other influenced disease that occurs for SARS-CoV-2 to CF.” | 0.98 | hgnc_dict_v1 |
| gene | TF | “The creation, destruction, or modulation of TF binding and function may be influenced by genetic modifications at TF binding sites that affect the binding affinity.” | 0.98 | hgnc_dict_v1 |
| gene | TF | “Overlapping transcription factor (TF) binding sites with lipid-associated loci identifies TFs relevant in lipid biology.” | 0.98 | hgnc_dict_v1 |
| gene | TF | “Protein-protein interaction (PPI) modular, functional enrichment, and feed-forward loop (FFL) analyses led to the identification of two key miRNAs, i.e., miR-222-3p and miR-125b-5p, which showed a strong association with the OAS3 gene and TRAF-type zinc finger domain containing 1 (TRAFD1) transcription factor (TF) based on essential centrality measures.” | 0.98 | hgnc_dict_v1 |
| gene | TF | “For cytological data, according to the highest asymmetry index (AsK%) and lowest total form percentage (TF%) values, genotype Ahs-670 was the most advanced cultivar, and genotype Bah-312 was the most primitive one.” | 0.98 | hgnc_dict_v1 |
| gene | TF | “Data analyses depicted that boll retention percentage, photosynthesis, stomatal conductance, relative water content under the stress conditions were associated with the presence of important drought & heat TF/genes which depicts high genetic potential of Pakistani cotton varieties against abiotic stress.” | 0.98 | hgnc_dict_v1 |
| gene | TF | “The basic helix-loop-helix (bHLH) is a TF gene family critical for plant growth and stress responses, including salinity.” | 0.98 | hgnc_dict_v1 |
| gene | TF | “Then, we used site-directed mutagenesis to induce knob-in-hole mutations in the human IgG heavy chain and the human lambda light chain to generate the bi-specific antibody (Bis-Ab) TF/RAP that binds both antigens simultaneously.” | 0.98 | hgnc_dict_v1 |
| gene | TF | “In this study, we model an SCGRN as a directed graph where an edge from a source node (also called transcription factor (TF)) to a target node (also called target gene) indicates that a TF regulates a target gene.” | 0.98 | hgnc_dict_v1 |
| gene | TF | “The pathway and gene ontology (GO) enrichment analysis, construction of protein-protein interaction (PPI) network, module analysis, construction of target genes-miRNA interaction network and target genes-transcription factor (TF) interaction network were performed using bioinformatics tools.” | 0.98 | hgnc_dict_v1 |
| gene | TF | “We screened expression profiling data to identify the transcription factor (TF) genes which are highly enriched in meningioma, and characterized the expression pattern of those TFs and downstream genes in clinical meningioma samples as well as normal brain tissues.” | 0.98 | hgnc_dict_v1 |
| gene | TF | “Quantitative analysis of gene expression of CD markers, OB cell markers, and transcription factors (TF) showed a high degree of similarity between the two cell populations (72%, 77%, and 81%, respectively).” | 0.98 | hgnc_dict_v1 |
| gene | TF | “RESULTS: We silenced ATG7 in HUVECs and observed >60% decreases in tumor necrosis factor (TNF)-α-induced tissue factor (TF) transcript levels, protein expression, and activity.” | 0.98 | hgnc_dict_v1 |
| gene | TF | “This mutation may result in disruption of the predicted H-bonding between residue Glu51 of FX and the Asn199 residue of the tissue factor (TF) in the FX/TF/factor VIIa ternary complex, producing the phenotype 'FX deficiency Riyadh', with prolonged PT and normal PTT.” | 0.98 | hgnc_dict_v1 |
| gene | TF | “Serum protein polymorphisms in Arab Moslems and Druze of Israel: BF, F13B, AHSG, GC, PLG, PI, and TF.” | 0.98 | hgnc_dict_v1 |