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Phenotype profile

homocystinuria

SaudiVarKB evidence summary derived from retained literature mentions.

17Phenotype mentions
17Publications
2Associated gene records
9Associated variant records

Associated gene records

Co-mentioned in the same publications
GeneIdentifier / contextArticlesMentions
CBSHGNC:155033
MTHFRHGNC:743611

Associated variant records

Co-mentioned in the same publications
VariantIdentifier / contextArticlesMentions
c.969G>Ac.969G>A11
p.Trp323Xp.Trp323X11
p.Arg336Cysp.Arg336Cys11
p.Gly153Argp.Gly153Arg11
p.Thr257Metp.Thr257Met11
785C>G785C>G11
T262RT262R11
IVS17IVS1711
T833CT833C11

Associated population records

Co-mentioned in the same publications
PopulationIdentifier / contextArticlesMentions
Population record22
Saudi Arabia11
Saudi ArabiaCohort 2411
Saudi Arabia · Jeddah11
Population recordCohort 10011
Saudi Arabia · RiyadhCohort 3311
Population recordCohort 2811
Saudi ArabiaCohort 1311
Population recordCohort 2511
Saudi ArabiaCohort 13511
Saudi ArabiaCohort 2011
Saudi Arabia · RiyadhCohort 1711
Saudi ArabiaCohort 91011

Supporting publications

17 records
  1. 2026Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review).Molecular medicine reports1 mentions
  2. 2025Clinical, biochemical and molecular characteristics of classic homocystinuria in Saudi Arabia and the impact of newborn screening on prevention of the complications: A tertiary center experience.JIMD reports1 mentions
  3. 2025Incidence and risk factors of ocular complications among patients with homocystinuria in Saudi Arabia: a cross-sectional study.Annals of medicine and surgery (2012)1 mentions
  4. 2021The first Saudi baby with classic homocystinuria diagnosed by universal newborn screening.Saudi medical journal1 mentions
  5. 2021Molecular Evaluation of Exon 8 Cystathionine rs5742905T T>C Gene Polymorphism and Determination of its Frequency, Distribution Pattern, and Association with Susceptibility to Coronary Artery Disease in the North Indian Population.Cardiovascular & hematological disorders drug targets1 mentions
  6. 2020The Spectrum of Mutations of Homocystinuria in the MENA Region.Genes1 mentions
  7. 2019Homocysteine and Hyperhomocysteinaemia.Current medicinal chemistry1 mentions
  8. 2019Revising the Psychiatric Phenotype of Homocystinuria.Genetics in medicine : official journal of the American College of Medical Genetics1 mentions
  9. 2018Severe Crohn's Disease Manifestations in a Child with Cystathionine β-Synthase Deficiency.ACG case reports journal1 mentions
  10. 2013Retrospective review of visual outcome in operated lens subluxation.Saudi medical journal1 mentions
  11. 2012Clinical and molecular findings of 13 families from Saudi Arabia and a family from Sudan with homocystinuria.Clinical genetics1 mentions
  12. 2007Implementation of extended neonatal screening and a metabolic unit in the State of Qatar: developing and optimizing strategies in cooperation with the Neonatal Screening Center in Heidelberg.Journal of inherited metabolic disease1 mentions
  13. 2000Homocystinuria in the Arab population of Israel: identification of two novel mutations using DGGE analysis.Human mutation1 mentions
  14. 1999Classic homocystinuria: clinical, biochemical and radiological observations, and therapeutic outcome of 24 Saudi patients.Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit1 mentions
  15. 1998Saudi experience with classic homocystinuria.Annals of Saudi medicine1 mentions
  16. 1996Saudi aminoacidemias: a six-year study.Indian journal of pediatrics1 mentions
  17. 1992Neurometabolic diseases at a national referral center: five years experience at the King Faisal Specialist Hospital and Research Centre.Journal of child neurology1 mentions