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Gene profile

CLPP

HGNC:2084 · SaudiVarKB evidence summary derived from retained literature mentions.

3Gene mentions
3Publications
0Linked variants
6Associated phenotypes

Associated phenotypes

Co-mentioned in CLPP publications
PhenotypeIdentifierArticlesMentions
obesityHP:000151311
Alzheimer disease11
intellectual disabilityHP:000124911
hearing lossHP:000036511
Down syndrome11
infertility11

Linked variants

Variants normalized to CLPP
VariantHGVS / rsIDArticlesMentions

No normalized variants are linked to this gene.

Population context

Reported in the same publications
Country / regionGroupCohortArticles
Saudi Arabia1
Not specified3871

Supporting publications

3 records
  1. 2024Aging exacerbates oxidative stress and liver fibrosis in an animal model of Down Syndrome.AgingPubMed ↗
  2. 2018Primary Ovarian Insufficiency and Azoospermia in Carriers of a Homozygous PSMC3IP Stop Gain Mutation.The Journal of clinical endocrinology and metabolismPubMed ↗
  3. 2015Exome analysis identified a novel missense mutation in the CLPP gene in a consanguineous Saudi family expanding the clinical spectrum of Perrault Syndrome type-3.Journal of the neurological sciencesPubMed ↗