gastric cancer
SaudiVarKB evidence summary derived from retained literature mentions.
86Phenotype mentions
86Publications
50Associated gene records
36Associated variant records
Associated gene records
Co-mentioned in the same publications| Gene | Identifier / context | Articles | Mentions |
|---|---|---|---|
| BRCA1 | HGNC:1100 | 3 | 3 |
| TP53 | HGNC:11998 | 3 | 3 |
| BRCA2 | HGNC:1101 | 3 | 3 |
| TLR4 | HGNC:11850 | 3 | 3 |
| STAT3 | HGNC:11364 | 2 | 2 |
| PTEN | HGNC:9588 | 2 | 2 |
| EGFR | HGNC:3236 | 2 | 2 |
| IDH1 | HGNC:5382 | 2 | 2 |
| TLR2 | HGNC:11848 | 2 | 2 |
| TNF | HGNC:11892 | 1 | 1 |
| NF1 | HGNC:7765 | 1 | 1 |
| APP | HGNC:620 | 1 | 1 |
| CD40 | HGNC:11919 | 1 | 1 |
| G6PD | HGNC:4057 | 1 | 1 |
| MPO | HGNC:7218 | 1 | 1 |
| IGF1 | HGNC:5464 | 1 | 1 |
| STAT4 | HGNC:11365 | 1 | 1 |
| HMOX1 | HGNC:5013 | 1 | 1 |
| BCL2 | HGNC:990 | 1 | 1 |
| AGL | HGNC:321 | 1 | 1 |
| ABCB1 | HGNC:40 | 1 | 1 |
| LDLR | HGNC:6547 | 1 | 1 |
| CTNNB1 | HGNC:2514 | 1 | 1 |
| VEGFA | HGNC:12680 | 1 | 1 |
| KRAS | HGNC:6407 | 1 | 1 |
| BRAF | HGNC:1097 | 1 | 1 |
| MUC4 | HGNC:7514 | 1 | 1 |
| ATM | HGNC:795 | 1 | 1 |
| CCL20 | HGNC:10619 | 1 | 1 |
| MALAT1 | HGNC:29665 | 1 | 1 |
| ASPM | HGNC:19048 | 1 | 1 |
| MSH6 | HGNC:7329 | 1 | 1 |
| THBS2 | HGNC:11786 | 1 | 1 |
| TYMS | HGNC:12441 | 1 | 1 |
| JAK2 | HGNC:6192 | 1 | 1 |
| ATP8B1 | HGNC:3706 | 1 | 1 |
| STK11 | HGNC:11389 | 1 | 1 |
| ESR1 | HGNC:3467 | 1 | 1 |
| TP73 | HGNC:12003 | 1 | 1 |
| CD44 | HGNC:1681 | 1 | 1 |
| TLR3 | HGNC:11849 | 1 | 1 |
| JAK1 | HGNC:6190 | 1 | 1 |
| PLCE1 | HGNC:17175 | 1 | 1 |
| FTO | HGNC:24678 | 1 | 1 |
| ARID1A | HGNC:11110 | 1 | 1 |
| ZFP36 | HGNC:12862 | 1 | 1 |
| GSTM1 | HGNC:4632 | 1 | 1 |
| KIF2A | HGNC:6318 | 1 | 1 |
| RPL27A | HGNC:10329 | 1 | 1 |
| CD200R1 | HGNC:24235 | 1 | 1 |
Associated variant records
Co-mentioned in the same publications| Variant | Identifier / context | Articles | Mentions |
|---|---|---|---|
| p.W577C | p.W577C | 1 | 1 |
| G894T | G894T | 1 | 1 |
| p.R304Q | p.R304Q | 1 | 1 |
| p.R175H | p.R175H | 1 | 1 |
| rs2770150 | rs2770150 | 1 | 1 |
| A2143G | A2143G | 1 | 1 |
| rs187084 | rs187084 | 1 | 1 |
| p.Ala1823Ser | p.Ala1823Ser | 1 | 1 |
| rs3804099 | rs3804099 | 1 | 1 |
| rs3804100 | rs3804100 | 1 | 1 |
| rs352140 | rs352140 | 1 | 1 |
| rs4986790 | rs4986790 | 1 | 1 |
| rs4986791 | rs4986791 | 1 | 1 |
| rs5744174 | rs5744174 | 1 | 1 |
| rs187084 | rs187084 | 1 | 1 |
| rs3804100 | rs3804100 | 1 | 1 |
| rs11536889 | rs11536889 | 1 | 1 |
| rs11536878 | rs11536878 | 1 | 1 |
| rs10116253 | rs10116253 | 1 | 1 |
| rs1927911 | rs1927911 | 1 | 1 |
| rs10983755 | rs10983755 | 1 | 1 |
| rs10759932 | rs10759932 | 1 | 1 |
| rs1927914 | rs1927914 | 1 | 1 |
| rs10004195 | rs10004195 | 1 | 1 |
| c.1337C>A | c.1337C>A | 1 | 1 |
| c.2076T>C | c.2076T>C | 1 | 1 |
| A2144G | A2144G | 1 | 1 |
| rs352140 | rs352140 | 1 | 1 |
| C3954T | C3954T | 1 | 1 |
| rs2275913 | rs2275913 | 1 | 1 |
| rs763780 | rs763780 | 1 | 1 |
| rs3748067 | rs3748067 | 1 | 1 |
| rs45445694 | rs45445694 | 1 | 1 |
| rs2853542 | rs2853542 | 1 | 1 |
| rs2274223 | rs2274223 | 1 | 1 |
| rs1799750 | rs1799750 | 1 | 1 |
Associated population records
Co-mentioned in the same publications| Population | Identifier / context | Articles | Mentions |
|---|---|---|---|
| Saudi Arabia | — | 2 | 2 |
| Population record | Cohort 114 | 1 | 1 |
| Saudi Arabia | Cohort 10 | 1 | 1 |
| Population record | Cohort 75 | 1 | 1 |
| Population record | Cohort 40 | 1 | 1 |
| Population record | Cohort 80 | 1 | 1 |
| Population record | Cohort 2 | 1 | 1 |
| Population record | Cohort 6 | 1 | 1 |
| Population record | Cohort 5 | 1 | 1 |
| Asir | — | 1 | 1 |
| Population record | Cohort 115 | 1 | 1 |
| Saudi Arabia | Cohort 3 | 1 | 1 |
| Population record | Cohort 200 | 1 | 1 |
| Population record | Cohort 30 | 1 | 1 |
| Population record | Cohort 108 | 1 | 1 |
| Saudi Arabia · Asir | — | 1 | 1 |
| Population record | Cohort 210 | 1 | 1 |
| Population record | Cohort 52 | 1 | 1 |
| Population record | Cohort 45 | 1 | 1 |
| Saudi Arabia · Hail | — | 1 | 1 |
| Saudi Arabia | Cohort 33 | 1 | 1 |
| Saudi Arabia | Cohort 68 | 1 | 1 |
| Saudi Arabia | Cohort 50 | 1 | 1 |
| Saudi Arabia | Cohort 245 | 1 | 1 |
| Saudi Arabia · Jeddah | Cohort 122 | 1 | 1 |
| Population record | Cohort 166 | 1 | 1 |
| Population record | Cohort 7,539 | 1 | 1 |
| Saudi Arabia | Cohort 210 | 1 | 1 |
| Population record | Cohort 5,816 | 1 | 1 |
| Population record | Cohort 831 | 1 | 1 |
| Population record | Cohort 520 | 1 | 1 |
| Population record | Cohort 412 | 1 | 1 |
| Population record | Cohort 8,124 | 1 | 1 |
| Saudi Arabia | Cohort 103 | 1 | 1 |
| Saudi Arabia | Cohort 368 | 1 | 1 |
Supporting publications
86 records- 2026STK11 and DNA Repair Gene Mutations Define Hereditary Subset of Middle Eastern Papillary Thyroid Cancer.International journal of molecular sciences1 mentions
- 2026Machine learning-based DNA microarray analysis for disease detection using the MICRO-AI framework.Science progress1 mentions
- 2026Immunohistochemistry and molecular detection of Helicobacter pylori infection and their virulent genes in gastric biopsies.Scientific reports1 mentions
- 2026An Integrated Machine Learning and Genomic Framework for Precise Detection of Gastric Cancer.The American journal of pathology1 mentions
- 2026The prevalence of gastric intestinal metaplasia in the Saudi population: a single-tertiary center retrospective study.Journal of gastrointestinal oncology1 mentions
- 2026Prognostic Value of Circulating Tumor DNA-Based Minimal Residual Disease for Recurrence-Free Survival in Resectable Gastric Cancer: A Systematic Review and Meta-Analysis with Serial Monitoring Analysis.Digestive diseases and sciences1 mentions
- 2026Quercetin targets IGF1 signaling in gastric cancer: a synergy of network pharmacology, molecular simulations, and in vitro functional assays.Journal of computer-aided molecular design1 mentions
- 2025Prevalence of SPOP and IDH Gene Mutations in Prostate Cancer in a Jordanian Population.Biochemical genetics1 mentions
- 2025Associations of HLA-G 3'UTR polymorphisms and increased HLA-G expression with gastric cancer susceptibility and prognosis.Immunobiology1 mentions
- 2025Deciphering the anticancer potential of thymoquinone: in-depth exploration of the potent flavonoid from Nigella sativa.Molecular biology reports1 mentions
- 2025Expressions of selected microRNAs in gastric cancer patients and their association with Helicobacter pylori and its cag pathogenicity island.Microbial pathogenesis1 mentions
- 2025DOMSCNet: a deep learning model for the classification of stomach cancer using multi-layer omics data.Briefings in bioinformatics1 mentions
- 2025Prevalence of HER2 expression and its association with clinicopathological parameters in gastric and gastroesophageal junction adenocarcinoma: A 10?year experience of an academic center.Molecular and clinical oncology1 mentions
- 2025Bee products in the fight against Helicobacter pylori and molecular interactions.Microbial pathogenesis1 mentions
- 2025Lactobacillus plantarum with lignin prevents Helicobacter pylori mediated DSS-colitis through improved intestinal integrity and reducing colonic inflammation in C57BL/6J mice.Journal of the science of food and agriculture1 mentions
- 2025Multi-omics analysis of Helicobacter pylori-associated gastric cancer identifies hub genes as a novel therapeutic biomarker.Briefings in bioinformatics1 mentions
- 2025Update on molecular pathogenesis of Helicobacter pylori-induced gastric cancer.World journal of gastrointestinal pathophysiology1 mentions
- 2025A Comprehensive Review on the Molecular Mechanism of Lycopene in Cancer Therapy.Food science & nutrition1 mentions
- 2025Promotive role of MBNL3 and PXN genes expressions with lncRNA PXN-AS1-L on gastric cancer.Biochemistry and biophysics reports1 mentions
- 2025TRIM26 as a dual regulator of ferroptosis and chemoresistance in gastric cancer through HSF1 ubiquitination and exosomal miR-24-3p signaling.Translational oncology1 mentions
- 2025Reviewing the Developing Significance of the Serine Protease PRSS23.Frontiers in bioscience (Landmark edition)1 mentions
- 2025Global burden of 292 causes of death in 204 countries and territories and 660 subnational locations, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.Lancet (London, England)1 mentions
- 2025Her4 in gastric adenocarcinoma and its association with molecular prognostic markers Ki-67 proliferation index and p53 mutational status in Saudis: A study at a tertiary care hospital in Eastern Saudi Arabia.Journal of family & community medicine1 mentions
- 2025Integrative analysis of Helicobacter pylori-driven stomach adenocarcinoma reveals epigenetic deregulation, immune evasion, and therapeutic resistance.Hereditas1 mentions
- 2025Effects of atranorin on the proliferation, apoptosis and metastasis of two different gastric cancer cell lines and exploring underlying mechanisms.Molecular biology reports1 mentions
- 2024A novel therapeutic approach to prevent Helicobacter pylori induced gastric cancer using networking biology, molecular docking, and simulation approaches.Journal of biomolecular structure & dynamics1 mentions
- 2024Li-Fraumeni Syndrome with Unusual Synchronous Malignancies: A Case Report.Case reports in oncology1 mentions
- 2024Caralluma pauciflorabased Ag-NPs activate ROS - induced apoptosis through down-regulation of AKT, mTOR and pI3K signaling in human gastric cancer (AGS) cells.Nanotechnology1 mentions
- 2024Biomarker discovery and validation for gastrointestinal tumors: A comprehensive review of colorectal, gastric, and liver cancers.Pathology, research and practice1 mentions
- 2024Harnessing the supremacy of MEG3 LncRNA to defeat gastrointestinal malignancies.Pathology, research and practice1 mentions
- 2024A Systems Biology Approach Unveils a Critical Role of DPP4 in Upper Gastrointestinal Cancer Patient Outcomes.Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer1 mentions
- 2024Dual primary gastric and colorectal cancer: The known hereditary causes and underlying mechanisms.World journal of gastrointestinal oncology1 mentions
- 2024Gene content, phage cycle regulation model and prophage inactivation disclosed by prophage genomics in the Helicobacter pylori Genome Project.Gut microbes1 mentions
- 2024P53-associated lncRNAs regulate immune functions and RNA-modifiers in gastric cancer.Heliyon1 mentions
- 2024Reducing metastasis ability of gastric cancer cell line by targeting MMP16 using miR-193a-5p and 5-FU.Advances in medical sciences1 mentions
- 2024Advanced CNN models in gastric cancer diagnosis: enhancing endoscopic image analysis with deep transfer learning.Frontiers in oncology1 mentions
- 2024Elucidating gastric cancer mechanisms and therapeutic potential of Adociaquinone A targeting EGFR: A genomic analysis and Computer Aided Drug Design (CADD) approach.Journal of cellular and molecular medicine1 mentions
- 2024Exploration of BRCA1 and BRCA2 mutations in gastric cancer patients through next generation sequencing: implications for diagnosis and therapy.American journal of translational research1 mentions
- 2024Detection of genomic variants in BRCA1 and BRCA2 across gastric cancer patients using next generation sequencing.American journal of translational research1 mentions
- 2023Anti-cancer activity of guggulsterone by modulating apoptotic markers: a systematic review and meta-analysis.Frontiers in pharmacology1 mentions
- 2023Dissecting the genetic heterogeneity of gastric cancer.EBioMedicine1 mentions
- 2023A Framework for Prediction of Oncogenomic Progression Aiding Personalized Treatment of Gastric Cancer.Diagnostics (Basel, Switzerland)1 mentions
- 2023Mathematical Modeling of Clonal Interference by Density-Dependent Selection in Heterogeneous Cancer Cell Lines.Cells1 mentions
- 2023Herbal melanin modulates PGE2 and IL-6 gastroprotective markers through COX-2 and TLR4 signaling in the gastric cancer cell line AGS.BMC complementary medicine and therapies1 mentions
- 2023A state-of-art of underlying molecular mechanisms and pharmacological interventions/nanotherapeutics for cisplatin resistance in gastric cancer.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie1 mentions
- 2023PATHOLOGICAL SIGNIFICANCE OF CDH1/E-CADHERIN GERMLINE SEQUENCE VARIANTS IN BREAST CANCER PATIENTS.Experimental oncology1 mentions
- 2023Curcumin's Dose-Dependent Attenuation of Gastric Cancer Cell Progression Via the PI3K Pathway Blockade.Dose-response : a publication of International Hormesis Society1 mentions
- 2023Identification, Genome Sequencing, and Characterizations of Helicobacter pylori Sourced from Pakistan.Microorganisms1 mentions
- 2023Study of vacuolating cytotoxin A (vacA) genotypes of ulcerogenic and non-ulcerogenic strains of Helicobacter pylori and its association with gastric disease.Saudi journal of biological sciences1 mentions
- 2023Common variants in toll-like receptor family genes and risk of gastric cancer: a systematic review and meta-analysis.Frontiers in genetics1 mentions
- 2023Characterizing EBV-associated Gastric Carcinoma (EBVaGC): A deep dive into LMP1 expression patterns.Cellular and molecular biology (Noisy-le-Grand, France)1 mentions
- 2022Detection of clarithromycin resistance and 23SrRNA point mutations in clinical isolates of Helicobacter pylori isolates: Phenotypic and molecular methods.Saudi journal of biological sciences1 mentions
- 2022Identification of functional tumor necrosis factor-alpha promoter variants associated with Helicobacter pylori infection in the Sudanese population: Computational approach.World journal of gastroenterology1 mentions
- 2021High expression of bone morphogenetic protein 1 (BMP1) is associated with a poor survival rate in human gastric cancer, a dataset approaches.Genomics1 mentions
- 2021Association of Helicobacter pylori Infection and Host Cytokine Gene Polymorphism with Gastric Cancer.Canadian journal of gastroenterology & hepatology1 mentions
- 2021Hepatoid esophagogastric adenocarcinoma and tumoral heterogeneity: a case report.Journal of gastrointestinal oncology1 mentions
- 2020The Influence of IL-1B Gene Polymorphisms on H. pylori Infection and Triple Treatment Response Among Jordanian Population.The application of clinical genetics1 mentions
- 2020Investigating the pathogenic SNPs in BLM helicase and their biological consequences by computational approach.Scientific reports1 mentions
- 2020Association of toll-like receptors 2, 4, 9 and 10 genes polymorphisms and Helicobacter pylori-related gastric diseases in Saudi patients.Indian journal of medical microbiology1 mentions
- 2020Gastric carcinoma: Insights into risk factors, methods of diagnosis, possible lines of management, and the role of primary care.Journal of family medicine and primary care1 mentions
- 2019Prevalence of Her3 in gastric cancer and its association with molecular prognostic markers: a Saudi cohort based study.The Libyan journal of medicine1 mentions
- 2019Cycloastragenol can negate constitutive STAT3 activation and promote paclitaxel-induced apoptosis in human gastric cancer cells.Phytomedicine : international journal of phytotherapy and phytopharmacology1 mentions
- 2019Gene expression patterns of COX-1, COX-2 and iNOS in H. Pylori infected histopathological conditions.Microbial pathogenesis1 mentions
- 2019Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017: A Systematic Analysis for the Global Burden of Disease Study.JAMA oncology1 mentions
- 2018Incorporation of p-53 mutation status and Ki-67 proliferating index in classifying Her2-neu positive gastric adenocarcinoma.The Libyan journal of medicine1 mentions
- 2018Genetic polymorphisms of IL-17A rs2275913, rs3748067 and IL-17F rs763780 in gastric cancer risk: evidence from 8124 cases and 9873 controls.Molecular biology reports1 mentions
- 2018Detection of genetic alterations in gastric cancer patients from Saudi Arabia using comparative genomic hybridization (CGH).PloS one1 mentions
- 2018Right Temporal Brain Metastases Arising Three Years after Curative Resection of Gastric Cancer: A Case Report.The Gulf journal of oncology1 mentions
- 2017Detection and Genotyping of Helicobacter pylori among Gastric ulcer and Cancer Patients from Saudi Arabia.Pakistan journal of medical sciences1 mentions
- 2017Unique characteristics of ARID1A mutation and protein level in gastric and colorectal cancer: A meta-analysis.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2017Function of tumor necrosis factor alpha before and after mutation in gastric cancer.Saudi journal of biological sciences1 mentions
- 2016Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015) : Jeddah, Kingdom of Saudi Arabia. 30 November - 3 December 2015.BMC genomics1 mentions
- 2015Toll-like receptor gene polymorphisms and susceptibility to Epstein-Barr virus-associated and -negative gastric carcinoma in Northern China.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2015Delimiting Allelic Imbalance of TYMS by Allele-Specific Analysis.Medicine1 mentions
- 2015Comparison of variations detection between whole-genome amplification methods used in single-cell resequencing.GigaScience1 mentions
- 2014Helicobacter pylori and gastric cancer: Indian enigma.World journal of gastroenterology1 mentions
- 2014Cytopathic effects of toxogenic strains of Helicobacter pylori on different cell lines.Indian journal of pathology & microbiology1 mentions
- 2014Epidemiology and pattern of antibiotic resistance in Helicobacter pylori: scenario from Saudi Arabia.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2014Role of interstitial collagenase gene promoter polymorphism in the etiology of gastric cancer.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2014Phospholipase C epsilon 1 (PLCE1) haplotypes are associated with increased risk of gastric cancer in Kashmir Valley.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2013Study of the cytoxin-associated gene a (CagA gene) in Helicobacter pylori using gastric biopsies of Iraqi patients.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2013Role of tumor necrosis factor-α -308 G/A promoter polymorphism in gastric cancer.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2013Cytochrome P450 1A1, 2E1 and GSTM1 gene polymorphisms and susceptibility to colorectal cancer in the Saudi population.Asian Pacific journal of cancer prevention : APJCP1 mentions
- 2013Comparison of the virulence markers of Helicobacter pylori and their associated diseases in patients from Pakistan and Afghanistan.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2012Relationship between Helicobacter pylori virulence genes and clinical outcomes in Saudi patients.Journal of Korean medical science1 mentions
- 2007Helicobacter pylori cagA and iceA genotypes status and risk of peptic ulcer in Saudi patients.Saudi medical journal1 mentions