hepatitis C
SaudiVarKB evidence summary derived from retained literature mentions.
284Phenotype mentions
100Publications
50Associated gene records
50Associated variant records
Associated gene records
Co-mentioned in the same publications| Gene | Identifier / context | Articles | Mentions |
|---|---|---|---|
| TM6SF2 | HGNC:11861 | 3 | 3 |
| ISG15 | HGNC:4053 | 2 | 2 |
| TP53 | HGNC:11998 | 2 | 2 |
| TLR4 | HGNC:11850 | 2 | 2 |
| AFP | HGNC:317 | 2 | 2 |
| TLR3 | HGNC:11849 | 2 | 2 |
| DEPDC5 | HGNC:18423 | 2 | 2 |
| CCL5 | HGNC:10632 | 1 | 1 |
| TNF | HGNC:11892 | 1 | 1 |
| NAT2 | HGNC:7646 | 1 | 1 |
| AR | HGNC:644 | 1 | 1 |
| G6PD | HGNC:4057 | 1 | 1 |
| PTEN | HGNC:9588 | 1 | 1 |
| CFTR | HGNC:1884 | 1 | 1 |
| CRP | HGNC:2367 | 1 | 1 |
| CTLA4 | HGNC:2505 | 1 | 1 |
| IL10 | HGNC:5962 | 1 | 1 |
| PTGS2 | HGNC:9605 | 1 | 1 |
| LDLR | HGNC:6547 | 1 | 1 |
| CYP3A4 | HGNC:2637 | 1 | 1 |
| CYP2B6 | HGNC:2615 | 1 | 1 |
| MAF | HGNC:6776 | 1 | 1 |
| VDR | HGNC:12679 | 1 | 1 |
| CHRNA5 | HGNC:1959 | 1 | 1 |
| PCSK9 | HGNC:20001 | 1 | 1 |
| ACR | HGNC:126 | 1 | 1 |
| PCK1 | HGNC:8724 | 1 | 1 |
| SLC19A1 | HGNC:10937 | 1 | 1 |
| TLR7 | HGNC:15631 | 1 | 1 |
| CCR2 | HGNC:1603 | 1 | 1 |
| DPYD | HGNC:3012 | 1 | 1 |
| EGFR | HGNC:3236 | 1 | 1 |
| IL10RB | HGNC:5965 | 1 | 1 |
| SP1 | HGNC:11205 | 1 | 1 |
| LCAT | HGNC:6522 | 1 | 1 |
| ITPA | HGNC:6176 | 1 | 1 |
| HLA-A | HGNC:4931 | 1 | 1 |
| ADAM10 | HGNC:188 | 1 | 1 |
| USP18 | HGNC:12616 | 1 | 1 |
| APC | HGNC:583 | 1 | 1 |
| CACNA1S | HGNC:1397 | 1 | 1 |
| FOXO1 | HGNC:3819 | 1 | 1 |
| RYR1 | HGNC:10483 | 1 | 1 |
| MYC | HGNC:7553 | 1 | 1 |
| SFRP1 | HGNC:10776 | 1 | 1 |
| CCL2 | HGNC:10618 | 1 | 1 |
| ALB | HGNC:399 | 1 | 1 |
| LEP | HGNC:6553 | 1 | 1 |
| NEAT1 | HGNC:30815 | 1 | 1 |
| ACE2 | HGNC:13557 | 1 | 1 |
Associated variant records
Co-mentioned in the same publications| Variant | Identifier / context | Articles | Mentions |
|---|---|---|---|
| rs1800795 | rs1800795 | 3 | 3 |
| rs58542926 | rs58542926 | 2 | 2 |
| rs231775 | rs231775 | 1 | 1 |
| rs16969968 | rs16969968 | 1 | 1 |
| rs1801268 | rs1801268 | 1 | 1 |
| rs772226819 | rs772226819 | 1 | 1 |
| rs121434568 | rs121434568 | 1 | 1 |
| rs193922816 | rs193922816 | 1 | 1 |
| rs3826711 | rs3826711 | 1 | 1 |
| rs267606617 | rs267606617 | 1 | 1 |
| rs267606618 | rs267606618 | 1 | 1 |
| rs267606619 | rs267606619 | 1 | 1 |
| rs4673993 | rs4673993 | 1 | 1 |
| rs1051266 | rs1051266 | 1 | 1 |
| rs2242480 | rs2242480 | 1 | 1 |
| rs11881222 | rs11881222 | 1 | 1 |
| rs115545701 | rs115545701 | 1 | 1 |
| rs2243250 | rs2243250 | 1 | 1 |
| -174G>C | -174G>C | 1 | 1 |
| -1363G>T | -1363G>T | 1 | 1 |
| rs2069827 | rs2069827 | 1 | 1 |
| rs1199520604 | rs1199520604 | 1 | 1 |
| rs12979860 | rs12979860 | 1 | 1 |
| rs4986790 | rs4986790 | 1 | 1 |
| rs4986791 | rs4986791 | 1 | 1 |
| E14K | E14K | 1 | 1 |
| p.I148M | p.I148M | 1 | 1 |
| p.E167K | p.E167K | 1 | 1 |
| rs115629050 | rs115629050 | 1 | 1 |
| rs4513095 | rs4513095 | 1 | 1 |
| rs12979860 | rs12979860 | 1 | 1 |
| rs2834167 | rs2834167 | 1 | 1 |
| rs6741425 | rs6741425 | 1 | 1 |
| rs1127354 | rs1127354 | 1 | 1 |
| rs1544410 | rs1544410 | 1 | 1 |
| D258E | D258E | 1 | 1 |
| T282S | T282S | 1 | 1 |
| A307G | A307G | 1 | 1 |
| V1196A | V1196A | 1 | 1 |
| V1158I | V1158I | 1 | 1 |
| D1194A | D1194A | 1 | 1 |
| R1181K | R1181K | 1 | 1 |
| T1080S | T1080S | 1 | 1 |
| Q1106R | Q1106R | 1 | 1 |
| V1062A | V1062A | 1 | 1 |
| S1148G | S1148G | 1 | 1 |
| A1182V | A1182V | 1 | 1 |
| Y2065N | Y2065N | 1 | 1 |
| M2000T | M2000T | 1 | 1 |
| L2003V | L2003V | 1 | 1 |
Associated population records
Co-mentioned in the same publicationsSupporting publications
100 records- 2026Direct-acting antiviral therapy in HCV patients: a retrospective study of the pre- and post-treatment impact in Saudi Arabia.BMC infectious diseases1 mentions
- 2026Fundamental concepts of convergent (parallel) evolution in human-pathogenic viruses and their implications for global health.Virology1 mentions
- 2026Transfusion-transmitted infections among blood donors in Saudi Arabia: demographic and malaria risk differences by donation purpose.Hematology (Amsterdam, Netherlands)1 mentions
- 2026Cardiac safety of sofosbuvir-based direct-acting antivirals in hepatitis C patients with pre-existing heart disease.Clinics (Sao Paulo, Brazil)1 mentions
- 2026Perceived preparedness and educational gaps in post-exposure prophylaxis among dental students in Saudi Arabia: a nationwide survey.BMC oral health1 mentions
- 2026Seroprevalence and Demographic Distribution of Blood-Borne Viral Infections among Hemodialysis Patients in Sudan: A Multicenter Study from Conflict-Affected Khartoum State.Virology journal1 mentions
- 2026"Seroprevalence and Associated Factors of Hepatitis B, Hepatitis C, and Human Immunodeficiency Virus Among Haemodialysis Patients in Morocco.Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia1 mentions
- 2025HCV and HBV genotypes: vital in the progression of HCV/ HBV co-infection.BMC gastroenterology1 mentions
- 2025SARS-CoV-2 S, M, and E Structural Glycoproteins Differentially Modulate Endoplasmic Reticulum Stress Responses.International journal of molecular sciences1 mentions
- 2025Prevalence and Factors Associated With Hepatitis C Virus in Riyadh, Saudi Arabia: A Large Cross-Sectional Study.Journal of epidemiology and global health1 mentions
- 2025An 11-year retrospective study on hepatitis C in Saudi Arabia: Seroconversion, recovery rates, and viral genotype distribution.Virology1 mentions
- 2025The Dual Burden of Hepatitis B and C Among Drug Users in Asia: The First Systematic Review and Meta-Analysis.Pathogens (Basel, Switzerland)1 mentions
- 2025Unveiling the heritability of selected unexplored pharmacogenetic markers in the Saudi population.Frontiers in pharmacology1 mentions
- 2025Evaluating the Linkage Between Resistin and Viral Seropositivity in Psoriasis: Evidence from a Tertiary Centre.Life (Basel, Switzerland)1 mentions
- 2025Identifying potent natural inhibitors of the hepatitis C virus NS3 protein using multiple computational and molecular approaches.Computers in biology and medicine1 mentions
- 2025Epidemiology of hepatitis B, hepatitis C, and syphilis co-infections in HIV-1 patients: a retrospective cross-sectional study of prevalence and viral load correlates.Annals of Saudi medicine1 mentions
- 2025Direct-acting antiviral treatment significantly shaped the gut microbiota in chronic hepatitis C patients: a pilot study.Frontiers in microbiology1 mentions
- 2025Prevalence, risk factors, and prevention strategies for intraoperative sharp object injuries among orthopedic surgeons: A cross-sectional study.Medicine1 mentions
- 2025HCV genotyping and rational computational designing of an immunogenic multiepitope vaccine against genotype 3a.Journal of computer-aided molecular design1 mentions
- 2025Understanding Oral Lichen Planus and Its Malignant Potential in the Saudi Arabian Population: A Systematic Review.Oral health & preventive dentistry1 mentions
- 2025Hepatitis C Direct-Acting Antivirals in the Immunosuppressed Host: Mechanisms, Interactions, and Clinical Outcomes.Viruses1 mentions
- 2025Network pharmacology and molecular docking reveal antiviral mechanisms of silver nanoparticles synthesized by Oscillatoria sp. against HCV pathogenesis.Scientific reports1 mentions
- 2025Non-coding RNAs in the viral host-pathogen interaction: molecular regulation and therapeutic potential.Frontiers in cellular and infection microbiology1 mentions
- 2024Utility of a microRNA panel in diagnosis and prognosis of hepatitis C-associated hepatocellular carcinoma.Laboratory medicine1 mentions
- 2024Beyond genotype-4: Direct-acting antiviral agents in patients with chronic hepatitis C infection from the Eastern Province of Saudi Arabia.Health science reports1 mentions
- 2024Efficacy and safety of glecaprevir and pibrentasvir in Saudi patients with chronic hepatitis C virus infection at a major tertiary hospital.Saudi medical journal1 mentions
- 2024Assessment of ubiquitin specific Peptidase-18 gene in peripheral blood of chronic hepatitis C patients treated with direct-acting antiviral drugs.Heliyon1 mentions
- 2024Inhibition of Cellular Factor TM6SF2 Suppresses Secretion Pathways of Hepatitis B, Hepatitis C, and Hepatitis D Viruses.The Journal of infectious diseases1 mentions
- 2024Hepatitis B and Hepatitis C Infections among Female Inmates in a Prison in Jeddah, Saudi Arabia.Clinical laboratory1 mentions
- 2024Potential use of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibition and prevention method in viral infection.Microbial cell factories1 mentions
- 2024Determination of IL-6 Gene Promoter Polymorphism in Patients with Hepatitis C and Its Impact on RNA Secondary Structure.Medicina (Kaunas, Lithuania)1 mentions
- 2024In silico design of a novel multi-epitope vaccine against HCV infection through immunoinformatics approaches.International journal of biological macromolecules1 mentions
- 2024Determination of hepatitis C virus subtype prevalent in Sindh, Pakistan: a phylogenetic analysis.Scientific reports1 mentions
- 2024Prevalence of hepatitis B and C infections among HIV-positive men who have sex with men: A systematic review and meta-analysis.Health science reports1 mentions
- 2024Impact of bedaquiline regimen on the treatment success rates of multidrug-resistant tuberculosis patients in Egypt.Scientific reports1 mentions
- 2024Circulating microRNAs as potential biomarkers of physical activity in geriatric patients with HCV.BMC molecular and cell biology1 mentions
- 2024Overview of Hepatitis B Vaccine Non-Response and Associated B Cell Amnesia: A Scoping Review.Pathogens (Basel, Switzerland)1 mentions
- 2024A literature review of genetics and epigenetics of HCV-related hepatocellular carcinoma: translational impact.Hepatobiliary surgery and nutrition1 mentions
- 2024Hepatitis B Virus, Hepatitis C Virus, and Human Immunodeficiency Virus Infection Among Premarital Screening Individuals in Saudi Arabia.International journal of public health1 mentions
- 2024The HCV-Melanoma Paradox: First Multi-Cohort and Molecular Net-Work Analysis Reveals Lower Incidence but Worse Outcomes-Integrating Clinical, Real-World, and In Silico Data.Medicina (Kaunas, Lithuania)1 mentions
- 2024Efficacy and Safety of Ombitasvir/Paritaprevir/Ritonavir Plus Dasabuvir in Treating HCV Genotypes 1 and 4 in Patients with Advanced Chronic Kidney Disease.Journal of pharmacy & bioallied sciences1 mentions
- 2024Association of IL-6 G-174C (rs1800795) variant with the susceptibility to hepatocellular carcinoma in patients with chronic hepatitis.Journal of the Egyptian National Cancer Institute1 mentions
- 2024Vesicular Stomatitis Virus as a Platform for Protease Activity Measurements.Current protocols1 mentions
- 2024Outcomes of the premarital screening program in Riyadh Region, KSA in 2021-2022: A cross-sectional study.Journal of Taibah University Medical Sciences1 mentions
- 2024The 14-bp insertion/deletion as a promising gene polymorphism to understand cancer risk: Evidence from a systematic review and comprehensive meta-analysis.Heliyon1 mentions
- 2024Exploring the potential of some natural indoles as antiviral agents: quantum chemical analysis, inverse molecular docking, and affinity calculations.Frontiers in chemistry1 mentions
- 2023High prevalence of vitamin D deficiency in HIV-infected individuals in comparison with the general population across Punjab province, Pakistan.Saudi journal of biological sciences1 mentions
- 2023Efficacy of generic sofosbuvir with daclatasvir compared to sofosbuvir/ledipasvir in genotype 4 hepatitis C virus: A prospective comparison with historical control.Health science reports1 mentions
- 2023Elucidating the role of missense SNP of protein kinase C epsilon in HCV-induced hepatocellular carcinoma.BMC cancer1 mentions
- 2023Sub-genotypes of hepatitis C virus in the Middle East and North Africa: Patterns of distribution and temporal changes.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases1 mentions
- 2023Genotypes of Hepatitis C Virus and Efficacy of Direct-Acting Antiviral Drugs among Chronic Hepatitis C Patients in a Tertiary Care Hospital.Tropical medicine and infectious disease1 mentions
- 2023Insights into Synonymous Codon Usage Bias in Hepatitis C Virus and Its Adaptation to Hosts.Pathogens (Basel, Switzerland)1 mentions
- 2023Safety and efficacy of elbasvir/grazoprevir in patients infected with hepatitis C virus genotype 4 in Qassim region of Saudi Arabia.International journal of health sciences1 mentions
- 2023Clostridium paraputrificum Bacteremia in a Patient with Human Immunodeficiency Virus Infection: A Case Report and Literature Review.Infection and drug resistance1 mentions
- 2023Oncogenic Viruses-Encoded microRNAs and Their Role in the Progression of Cancer: Emerging Targets for Antiviral and Anticancer Therapies.Pharmaceuticals (Basel, Switzerland)1 mentions
- 2023Transcriptional Analysis of TP53 Gene in Chronic Hepatitis C Patients Treated with Sofosbuvir, Daclatasvir, Pegylated Interferon, and Ribavirin.ACS omega1 mentions
- 20235-Membered Heterocyclic Compounds as Antiviral Agents.Current topics in medicinal chemistry1 mentions
- 2023Bioinformatics and network pharmacology-based study to elucidate the multi-target pharmacological mechanism of the indigenous plants of Medina valley in treating HCV-related hepatocellular carcinoma.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society1 mentions
- 2023Prevalence of Hepatitis B Virus, Hepatitis C Virus, and HIV Infections in Hemodialysis Patients at Kano Kidney Center.Cureus1 mentions
- 2023Differential expression of "A Disintegrin and Metalloproteinase 10" in hepatocellular carcinoma and the noncancerous hepatic tissues: Contribution to HCV-promoted hepatocarcinogenesis.Indian journal of pathology & microbiology1 mentions
- 2023Investigating pathogenic SNP of PKCι in HCV-induced hepatocellular carcinoma.Scientific reports1 mentions
- 2023Sustained virological response to antiviral drugs in treatment of different genotypes of HCV cirrhotic patients.Pakistan journal of pharmaceutical sciences1 mentions
- 2023Experience with direct-acting antivirals in genotype 1-5 infected chronic hepatitis C patients in Turkey.Annals of Saudi medicine1 mentions
- 2023Molecular Mechanisms of Resistance to Direct-Acting Antiviral (DAA) Drugs for the Treatment of Hepatitis C Virus Infections.Diagnostics (Basel, Switzerland)1 mentions
- 2023The Potential Role of Circulating Long Miscellaneous RNAs in the Diagnosis and Prognosis of Hepatitis C Related Hepatocellular Carcinoma.Non-coding RNA1 mentions
- 2023Effectiveness of generic sofosbuvir in the treatment of chronic hepatitis C virus infection in Saudi patients.Saudi medical journal1 mentions
- 2023Harnessing Nature's Gifts: Salix nigra and Its Potential for Combating Hepatitis C Virus (HCV).ACS omega1 mentions
- 2023A novel candidate hepatitis C virus genotype 4 subtype identified by next generation sequencing full-genome characterization in a patient from Saudi Arabia.Frontiers in microbiology1 mentions
- 2023A multicentric and nationwide predictive study role of T cell sub-population in the prevalence and prognosis of cryoglobulinemia among genotype 4 chronic hepatitis C patients.Journal of medical virology1 mentions
- 2023The Knowledge, Attitude, and Perception of Needlestick Injuries Among Dental Students in Riyadh, Kingdom of Saudi Arabia: A Cross-Sectional Survey.Cureus1 mentions
- 2023Prevalence of Hepatitis C Virus Infection and Efficacy of Sofosbuvir-Velpatasvir and Sofosbuvir-Daclatasvir Treatment Regimens in End-stage Renal Disease Patients on Maintenance Hemodialysis.Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia1 mentions
- 2022Hepatitis C positive organ transplantation to negative recipients at a multiorgan Canadian transplant centre: ready for prime time.BMC gastroenterology1 mentions
- 2022Patient-specific genetic factors predict treatment failure in sofosbuvir-treated patients with chronic hepatitis C.Liver international : official journal of the International Association for the Study of the Liver1 mentions
- 2022The efficacy of Elbasvir/Grazoprevir fixed-dose combination for 8 weeks in HCV treatment and health-related quality of life (HRQoL) in treatment-naïve, non-cirrhotic, genotype 4-infected patients (ELEGANT-4): A single-center, single-arm, open-label, phase 3 trial.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association1 mentions
- 2022Deciphering the Significance of Plasma Chemokines as Prognostic Biomarkers in Pegylated IFN-Α-2a /Ribavirin-Treated Chronic Hepatitis C Genotype 4 Patients.Infectious disorders drug targets1 mentions
- 2022Drug delivery of sofosbuvir drug capsulated with the β-cyclodextrin basket loaded on chitosan nanoparticle surface for anti-hepatitis C virus (HCV).International journal of biological macromolecules1 mentions
- 2022GLUT1 and ASCT2 Protein Expression in Papillary Thyroid Carcinoma Patients and Relation to Hepatitis C Virus: A Propensity-Score Matched Analysis.International journal of general medicine1 mentions
- 2022Hepatic fibrosis changes in patients with chronic hepatitis C infection who respond to direct-acting antivirals.Annals of Saudi medicine1 mentions
- 2022Needlestick injuries in radiology: prevention and management.Clinical radiology1 mentions
- 2022Knowledge and attitude of Engaged and Recently Married Couples Toward Premarital Screening: A Cross-Sectional Study.Inquiry : a journal of medical care organization, provision and financing1 mentions
- 2022Association of CTLA-4 and IL-4 polymorphisms in viral induced liver cancer.BMC cancer1 mentions
- 2022A Rare Case of Didanosine-Induced Mid-Peripheral Chorioretinal Atrophy Identified Incidentally 11 Years after the Drug Cessation.Medicina (Kaunas, Lithuania)1 mentions
- 2022Prevalence of Transfusion-Transmitted Infections (HCV, HIV, Syphilis and Malaria) in Blood Donors: A Large-Scale Cross-Sectional Study.Pathogens (Basel, Switzerland)1 mentions
- 2022Patterns of Hepatitis B, Hepatitis C and HIV Among Blood Donors in Samtah-Jazan Region.Journal of epidemiology and global health1 mentions
- 2022PNPLA3 and TM6SF2 genetic variants and hepatic fibrosis and cirrhosis in Pakistani chronic hepatitis C patients: a genetic association study.BMC gastroenterology1 mentions
- 2022Hepatitis C Virus Infection and Intrinsic Disorder in the Signaling Pathways Induced by Toll-Like Receptors.Biology1 mentions
- 2022Integrated analysis to study the interplay between post-translational modifications (PTM) in hepatitis C virus proteins and hepatocellular carcinoma (HCC) development.Scientific reports1 mentions
- 2022System biology approaches identified novel biomarkers and their signaling pathways involved in renal cell carcinoma with different human diseases.Bioscience reports1 mentions
- 2022The effectiveness and safety of direct-acting antivirals for hepatitis C virus treatment: A single-center experience in Saudi Arabia.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society1 mentions
- 2022Prevalence of transfusion-transmitted infections in Saudi Arabia blood donors: A nationwide, cross-sectional study.Saudi medical journal1 mentions
- 2022Interplay between TGF-b1 and miRNA-122 biomarkers in hepatocellular carcinoma progression in patients with chronic hepatitis C.Tropical biomedicine1 mentions
- 2022Evaluation of Hematological, Biochemical Profiles and Molecular Detection of Envelope Gene (gp-41) in Human Immunodeficiency Virus (HIV) among Newly Diagnosed Patients.Medicina (Kaunas, Lithuania)1 mentions
- 2021Association of the polymorphism of the Toll-like receptor (TLR)-3 and TLR-9 genes with hepatitis C virus-specific cell-mediated immunity outcomes among Egyptian health-care workers.Clinical and experimental immunology1 mentions
- 2021Consensus small interfering RNA targeted to stem-loops II and III of IRES structure of 5' UTR effectively inhibits virus replication and translation of HCV sub-genotype 4a isolates from Saudi Arabia.Saudi journal of biological sciences1 mentions
- 2021Resistance Associated Mutations in HCV Patients Failing DAA Treatment.The new microbiologica1 mentions
- 2021Sofosbuvir plus ribavirin combination regimen boost liver functions and antioxidant profile in hepatitis C virus patients.Microbial pathogenesis1 mentions
- 2021Treating paediatric hepatitis C in the era of direct-acting antiviral agents.Liver international : official journal of the International Association for the Study of the Liver1 mentions
- 2021Narrative Review of Infection Control Knowledge and Attitude among Healthcare Workers.Journal of epidemiology and global health1 mentions
- 2021Hepatitis B-C and human immunodeficiency virus: seroprevalence and associated factors among health students in Saudi Arabia.Hospital practice (1995)1 mentions
- 2021Occult hepatitis C virus infection in the Middle East and Eastern Mediterranean countries: A systematic review and meta-analysis.World journal of hepatology1 mentions