APOL1
HGNC:618 · SaudiVarKB evidence summary derived from retained literature mentions.
5Gene mentions
5Publications
2Linked variants
5Associated phenotypes
Associated phenotypes
Co-mentioned in APOL1 publications| Phenotype | Identifier | Articles | Mentions |
|---|---|---|---|
| renal failure | — | 2 | 2 |
| hypertension | — | 1 | 1 |
| diabetes mellitus | — | 1 | 1 |
| sickle cell disease | HP:0001878 | 1 | 1 |
| nephrotic syndrome | — | 1 | 1 |
Linked variants
Variants normalized to APOL1| Variant | HGVS / rsID | Articles | Mentions |
|---|---|---|---|
| Rs60910145 | rs60910145 | 1 | 1 |
| S342G | — | 1 | 1 |
Population context
Reported in the same publications| Country / region | Group | Cohort | Articles |
|---|---|---|---|
| Not specified | — | 156 | 1 |
| Not specified | — | 69 | 1 |
| Not specified | — | 115 | 1 |
| Saudi Arabia | — | 119 | 1 |
Supporting publications
5 records- 2024Association of Normal and Mutated APOL1 G2 Rs60910145 alleles with SCD, Body Mass Index, and Renal Function Biomarkers and Indices.Current research in translational medicinePubMed ↗
- 2023Apolipoprotein L1 gene variants and kidney disease in patients with HIV: a systematic review and meta-analysis.Journal of nephrologyPubMed ↗
- 2022Genome-Wide Epistatic Interaction between DEF1B and APOL1 High-Risk Genotypes for Chronic Kidney Disease.Clinical journal of the American Society of Nephrology : CJASNPubMed ↗
- 2018HLA-DQA1 and APOL1 as Risk Loci for Childhood-Onset Steroid-Sensitive and Steroid-Resistant Nephrotic Syndrome.American journal of kidney diseases : the official journal of the National Kidney FoundationPubMed ↗
- 2018The prevalence of APOL1 gene variants in a cohort of renal disease patients in Western Saudi Arabia.Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi ArabiaPubMed ↗