recurrent pregnancy loss
SaudiVarKB evidence summary derived from retained literature mentions.
27Phenotype mentions
27Publications
50Associated gene records
23Associated variant records
Associated gene records
Co-mentioned in the same publications| Gene | Identifier / context | Articles | Mentions |
|---|---|---|---|
| MTHFR | HGNC:7436 | 3 | 3 |
| PGD | HGNC:8891 | 2 | 2 |
| ACE | HGNC:2707 | 2 | 2 |
| PAH | HGNC:8582 | 1 | 1 |
| COL1A2 | HGNC:2198 | 1 | 1 |
| APOE | HGNC:613 | 1 | 1 |
| F12 | HGNC:3530 | 1 | 1 |
| CD40 | HGNC:11919 | 1 | 1 |
| KCNQ1 | HGNC:6294 | 1 | 1 |
| G6PD | HGNC:4057 | 1 | 1 |
| AGL | HGNC:321 | 1 | 1 |
| ABCB1 | HGNC:40 | 1 | 1 |
| LDLR | HGNC:6547 | 1 | 1 |
| BRAF | HGNC:1097 | 1 | 1 |
| CCNO | HGNC:18576 | 1 | 1 |
| ASPM | HGNC:19048 | 1 | 1 |
| ATP8B1 | HGNC:3706 | 1 | 1 |
| EGFR | HGNC:3236 | 1 | 1 |
| ENTPD1 | HGNC:3363 | 1 | 1 |
| DNAH11 | HGNC:2942 | 1 | 1 |
| FGB | HGNC:3662 | 1 | 1 |
| ITGB3 | HGNC:6156 | 1 | 1 |
| CD44 | HGNC:1681 | 1 | 1 |
| FSHR | HGNC:3969 | 1 | 1 |
| APOB | HGNC:603 | 1 | 1 |
| FTO | HGNC:24678 | 1 | 1 |
| ZFP36 | HGNC:12862 | 1 | 1 |
| ROBO1 | HGNC:10249 | 1 | 1 |
| KIF2A | HGNC:6318 | 1 | 1 |
| RPL27A | HGNC:10329 | 1 | 1 |
| CD200R1 | HGNC:24235 | 1 | 1 |
| STAMBP | HGNC:16950 | 1 | 1 |
| CD226 | HGNC:16961 | 1 | 1 |
| IDH1 | HGNC:5382 | 1 | 1 |
| IDH2 | HGNC:5383 | 1 | 1 |
| OGT | HGNC:8127 | 1 | 1 |
| TMEM70 | HGNC:26050 | 1 | 1 |
| KCNE1 | HGNC:6240 | 1 | 1 |
| IL17A | HGNC:5981 | 1 | 1 |
| PLK1 | HGNC:9077 | 1 | 1 |
| NT5E | HGNC:8021 | 1 | 1 |
| F13A1 | HGNC:3531 | 1 | 1 |
| ASIC5 | HGNC:17537 | 1 | 1 |
| TLE6 | HGNC:30788 | 1 | 1 |
| NLRP7 | HGNC:22947 | 1 | 1 |
| ZP1 | HGNC:13187 | 1 | 1 |
| NLRP5 | HGNC:21269 | 1 | 1 |
| CCDC68 | HGNC:24350 | 1 | 1 |
| CBX3 | HGNC:1553 | 1 | 1 |
| CENPH | HGNC:17268 | 1 | 1 |
Associated variant records
Co-mentioned in the same publications| Variant | Identifier / context | Articles | Mentions |
|---|---|---|---|
| C677T | C677T | 1 | 1 |
| rs1801133 | rs1801133 | 1 | 1 |
| p.Gly506Asp | p.Gly506Asp | 1 | 1 |
| c.169_171del | c.169_171del | 1 | 1 |
| G20210A | G20210A | 1 | 1 |
| p.W577C | p.W577C | 1 | 1 |
| G894T | G894T | 1 | 1 |
| G1691A | G1691A | 1 | 1 |
| A4070G | A4070G | 1 | 1 |
| G20210A | G20210A | 1 | 1 |
| G103T | G103T | 1 | 1 |
| T1565C | T1565C | 1 | 1 |
| C677T | C677T | 1 | 1 |
| A1298C | A1298C | 1 | 1 |
| G10708A | G10708A | 1 | 1 |
| T388C | T388C | 1 | 1 |
| C526T | C526T | 1 | 1 |
| rs12976445 | rs12976445 | 1 | 1 |
| R506Q | R506Q | 1 | 1 |
| c.680G>T | c.680G>T | 1 | 1 |
| R227I | R227I | 1 | 1 |
| p.R227I | p.R227I | 1 | 1 |
| A20210G | A20210G | 1 | 1 |
Associated population records
Co-mentioned in the same publications| Population | Identifier / context | Articles | Mentions |
|---|---|---|---|
| Saudi Arabia | — | 2 | 2 |
| Saudi Arabia | — | 1 | 1 |
| Population record | Cohort 18 | 1 | 1 |
| Saudi Arabia | Cohort 2 | 1 | 1 |
| Population record | Cohort 2 | 1 | 1 |
| Population record | Cohort 103 | 1 | 1 |
| Population record | Cohort 2,431 | 1 | 1 |
| Population record | Cohort 162 | 1 | 1 |
| Population record | Cohort 60 | 1 | 1 |
| Saudi Arabia · Asir | — | 1 | 1 |
| Saudi Arabia | Cohort 19 | 1 | 1 |
| Population record | Cohort 180 | 1 | 1 |
| Saudi Arabia | Cohort 50 | 1 | 1 |
| Saudi Arabia | Cohort 585 | 1 | 1 |
| Population record | Cohort 4,030 | 1 | 1 |
| Saudi Arabia | Cohort 171 | 1 | 1 |
| Saudi Arabia | Cohort 400 | 1 | 1 |
Supporting publications
27 records- 2026Clinical utility of chromosomal microarray and whole exome sequencing in evaluating genetic causes for pregnancy loss using products of conception specimens.Journal of perinatal medicine1 mentions
- 2025High penetrance and phenotypic landscape of methylenetetrahydrofolate reductase c.665 C>T polymorphism in the absence of folate fortification.Clinical nutrition ESPEN1 mentions
- 2025Chromosomal abnormalities in couples with recurrent pregnancy loss: a 16-year cross-sectional study of 4030 cases from Turkey.Annals of Saudi medicine1 mentions
- 2025Potential association of certain microRNA gene polymorphisms with recurrent pregnancy loss susceptibility in Saudi women.PloS one1 mentions
- 2025Whole-Exome Sequencing in Recurrent Pregnancy Loss: Current Evidence and Future Directions in Saudi Arabia.Medical archives (Sarajevo, Bosnia and Herzegovina)1 mentions
- 2024Molecular cytogenetic analysis of multi-miscarriage products of conception in clinical cases from Al-Anbar Governorate, west of Iraq.Saudi journal of biological sciences1 mentions
- 2024Detection of human platelets antigen polymorphism (HPA-1 and HPA-3) and human factor XIII mutation in Sudanese women with recurrent pregnancy loss.BMC research notes1 mentions
- 2024Impact of Vitamin D deficiency on immunological and metabolic responses in women with recurrent pregnancy loss: focus on VDBP/HLA-G1/CTLA-4/ENTPD1/adenosine-fetal-maternal conflict crosstalk.BMC pregnancy and childbirth1 mentions
- 2024Investigating the complications of frequent pregnancy loss in patients referred to obstetrics and gynecology clinics at King Khalid University Hospital.Journal of family medicine and primary care1 mentions
- 2023Maternal Thrombophilic and Hypofibrinolytic Genetic Variants in Idiopathic Recurrent Pregnancy Loss: a Continuing Mystery.Reproductive sciences (Thousand Oaks, Calif.)1 mentions
- 2023Controversy and Consensus on Indications for Sperm DNA Fragmentation Testing in Male Infertility: A Global Survey, Current Guidelines, and Expert Recommendations.The world journal of men's health1 mentions
- 2023Classical phenylketonuria presenting as maternal PKU syndrome in the offspring of an intellectually normal woman.JIMD reports1 mentions
- 2023Homozygous missense variant F12 (Gly506Asp) associated with severe factor XII deficiency: a case report.Journal of medical case reports1 mentions
- 2022Recurrent spontaneous oocyte activation causes female infertility.Journal of assisted reproduction and genetics1 mentions
- 2022Implications of Decreased Expression of miR-125a with Respect to Its Variant Allele in the Pathogenesis of Recurrent Pregnancy Loss: A Study in a High Incidence Zone.Journal of clinical medicine1 mentions
- 2022Immunogenetic Role of IL17A Polymorphism in the Pathogenesis of Recurrent Miscarriage.Journal of clinical medicine1 mentions
- 2021Cytokine imbalance at materno-embryonic interface as a potential immune mechanism for recurrent pregnancy loss.International immunopharmacology1 mentions
- 2021Whole-Genome Sequencing Reveals Exonic Variation of ASIC5 Gene Results in Recurrent Pregnancy Loss.Frontiers in medicine1 mentions
- 2021Phenotypic characterization of NKT-like cells and evaluation of specifically related cytokines for the prediction of unexplained recurrent miscarriage.Heliyon1 mentions
- 2020A genomics approach to females with infertility and recurrent pregnancy loss.Human genetics1 mentions
- 2020Association between factor V Leiden mutation and recurrent pregnancy loss in the middle east countries: a Newcastle-Ottawa meta-analysis.Archives of gynecology and obstetrics1 mentions
- 2020Evaluation of etiology and pregnancy outcome in recurrent miscarriage patients.Saudi journal of biological sciences1 mentions
- 2019[Balanced translocation in a patient with abortus habitualis and normal karyotype].Ugeskrift for laeger1 mentions
- 2016Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015) : Jeddah, Kingdom of Saudi Arabia. 30 November - 3 December 2015.BMC genomics1 mentions
- 2016Associations of recurrent miscarriages with chromosomal abnormalities, thrombophilia allelic polymorphisms and/or consanguinity in Saudi Arabia.BMC medical genetics1 mentions
- 2016Lack of Association between Angiotensin Converting Enzyme I/D Polymorphism and Unexplained Recurrent Miscarriage in Saudi Arabia.Journal of medical biochemistry1 mentions
- 2014Clinical outcome of preimplantation genetic diagnosis and screening using next generation sequencing.GigaScience1 mentions