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Phenotype profile

Alstrom syndrome

SaudiVarKB evidence summary derived from retained literature mentions.

14Phenotype mentions
14Publications
13Associated gene records
9Associated variant records

Associated gene records

Co-mentioned in the same publications
GeneIdentifier / contextArticlesMentions
ALMS1HGNC:42877
PAHHGNC:858211
TBX4HGNC:1160311
LDLRHGNC:654711
GUCY2DHGNC:468911
SCN5AHGNC:1059311
CYP3A5HGNC:263811
PRDM13HGNC:1399811
MYCHGNC:755311
DDIT4HGNC:2494411
EPAS1HGNC:337411
SFRP1HGNC:1077611
TPMTHGNC:1201411

Associated variant records

Co-mentioned in the same publications
VariantIdentifier / contextArticlesMentions
c.2729C>Gc.2729C>G11
p.Ser910*p.Ser910*11
T376ST376S11
S909*S909*11
R2721*R2721*11
c.8158C>Tc.8158C>T11
p.R2720Xp.R2720X11
C.848dupAC.848dupA11
C.11870-2A>TC.11870-2A>T11

Associated population records

Co-mentioned in the same publications
PopulationIdentifier / contextArticlesMentions
Saudi Arabia44
Saudi Arabia22
Saudi Arabia · Riyadh11
Saudi Arabia · HailCohort 111
Saudi ArabiaCohort 10011
Saudi ArabiaCohort 511

Supporting publications

14 records
  1. 2024Unraveling Alström syndrome: Homozygous mutation c.2729C>G in ALMS1 gene across an extended family.Molecular genetics & genomic medicine1 mentions
  2. 2024Alström Syndrome: A Challenging Case Study of a Female Saudi Patient With Type 2 Diabetes Mellitus and Complete Vision Loss.Cureus1 mentions
  3. 2023Alström Syndrome: A Rare Cause of Severe Insulin Resistance.JCEM case reports1 mentions
  4. 2023Unique phenotypic-genotypic correlation in Saudi patients with ALMS1 mutations.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society1 mentions
  5. 2021Identification of a Rare Exon 19 Skipping Mutation in ALMS1 Gene in Alström Syndrome Patients From Two Unrelated Saudi Families.Frontiers in pediatrics1 mentions
  6. 2020Whole exome sequencing identifies rare biallelic ALMS1 missense and stop gain mutations in familial Alström syndrome patients.Saudi journal of biological sciences1 mentions
  7. 2017Alström syndrome: A novel mutation in Saudi girl with insulin-resistant diabetes.Medicine1 mentions
  8. 2017Erratum: Alström syndrome: A novel mutation in Saudi girl with insulin-resistant diabetes: Erratum.Medicine1 mentions
  9. 2016Novel Mutations in Two Saudi Patients with Congenital Retinal Dystrophy.Middle East African journal of ophthalmology1 mentions
  10. 2016Human genome meeting 2016 : Houston, TX, USA. 28 February - 2 March 2016.Human genomics1 mentions
  11. 2015Ophthalmic Features of Children Not Yet Diagnosed with Alstrom Syndrome.Ophthalmology1 mentions
  12. 2010Combined occurrence of diabetes mellitus and retinitis pigmentosa.Annals of Saudi medicine1 mentions
  13. 2009Allelic heterogeneity in inbred populations: the Saudi experience with Alström syndrome as an illustrative example.American journal of medical genetics. Part A1 mentions
  14. 2006Alstrom syndrome in four sibs from northern Jordan.Annals of Saudi medicine1 mentions