Population record
Saudi Arabia · 58 retained evidence mentions
Source-grounded findings
Supporting evidence
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| population | Saudi Arabia | “Impacts of Dietary Patterns and Screen Time on the Risk of Developing Type 2 Diabetes Mellitus Among Children in Saudi Arabia: A Cross-Sectional Study. In Saudi Arabia, rapid urbanization has led to shifts in eating habits and increased sedentary behaviors among children, warranting further investigation to better understand these risk factors. This study aims to examine the association between dietary patterns, screen time, and early markers of T2DM among children in Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Utilization Patterns and Barriers to Sodium-Glucose Cotransporter-2 Inhibitor Prescription in Patients with Heart Failure: Real-World Evidence from Saudi Arabia. This study aimed to assess real-world utilization of SGLT2i among patients with HF in Saudi Arabia and to identify clinical factors associated with prescribing and outcomes. METHODS: We conducted a multicenter retrospective cohort study of adult patients with HF receiving longitudinal care at tertiary cardiac centers between January 2016 and December 2024 in Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Molecular impact of single nucleotide polymorphisms in GIPR gene among type 2 diabetes mellitus patients in the Saudi population. This study aimed to identify the molecular role of 5 SNPs (rs1800436, rs1800437, rs2302382, rs10423928, and rs34125392) in the GIPR gene in patients with T2DM in the Saudi population.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “OBJECTIVE: In this article we systematically reviewed all the literature on UPS in Saudi Arabia and worldwide to formulate a clinical picture, a possible management algorithm and report noted outcomes. Post-operatively, the patient was doing well with no complaints (e.g., pain or discharges), however after 2 weeks the patient developed a small hematoma that was aspirated, other than that the follows ups were unremarkable.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Assessment of healing dynamics in dental extraction sockets among non-diabetic, prediabetic, and type 2 diabetic patients: a comparative clinical investigation. This study aims to evaluate the impact of diabetes on the healing of extraction sockets in non-diabetic, prediabetic, and type 2 diabetic patients in Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Distinct Circulating Biomarker Profiles Associated with Type 2 Diabetes in a Regional Cohort-A Cross-Sectional Study. Background: The prevalence of Type 2 diabetes mellitus (T2DM) has significantly increased in Saudi Arabia, rising from 16.8% in 2018 to 28% in 2023. Materials and Methods: A cross-sectional study was conducted by enrolling 114 T2DM patients and 91 healthy controls recruited from tertiary care centers in the Aljouf region, Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Study of gene polymorphisms in Toll-like receptor 2 in patients with acute lymphoblastic leukemia. CONCLUSIONS: This study shows that TLR2 could be an independent prognostic factor of ALL risks in the Saudi population.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “The Effect of Genetic Variants of SLC22A2 (rs662301 and rs315978) on the response to Metformin in type 2 Saudi diabetic patients. PURPOSE: To investigate the allelic and genotypic frequencies of the two genetic variations, NC_000006.12: g.160275887C > T (rs662301) and NC_000006.12:g.160231826 T > C (rs315978), in the SLC22A2 gene among the Saudi population. The primary goal is to elucidate potential associations with these genetic variations and the response to metformin therapy over 6 months to enhance our knowledge of the genetic basis of Type 2 Diabetes Mellitus (T2DM) and its clinical management in the Saudi population. MATERIALS/METHODS: 76 newly diagnosed T2DM patients, aged 30 to 60, of both sexes and Saudi origin, were treated with metformin monotherapy. CONCLUSION: The study offers insights into the genetic landscape of T2DM in Saudi Arabia. This study serves as a foundation for future investigations into the Saudi population, recognizing the need for a larger sample size.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Characteristics and clinical manifestations of patients, including organ transplant patients, during the surge of JN.1: Insights from Saudi Arabia. This study reports on the characteristics and clinical manifestations of patients during the surge of the JN.1 variant in Saudi Arabia; it also investigates the evolution of SARS-CoV-2 variants in organ transplant patients and identifies patient risk factors.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Genomic Surveillance and Mutation Analysis of SARS-CoV-2 Variants among Patients in Saudi Arabia. This study aimed to sequence the whole genome of SARS-CoV-2 and detect the variants present in specimens from Saudi Arabia. A total of 1161 samples from patients diagnosed with COVID-19 in Saudi Arabia, between 1 April 2021 and 31 July 2023, were analyzed.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Severity of scorpion envenomation in Saudi Arabia: A systematic review. Over the course of five years, 72,168 scorpion stings were recorded in Saudi Arabia. The purpose of this systematic review is, thus, to explore the signs and symptoms of scorpion envenomation victims in Saudi Arabia and classify them using the Abroug's severity scale. This review identified 49 articles published between January 1953 and September 2024 on scorpion sting incidents in Saudi Arabia. Class II systemic symptoms, such as hypertension, tachycardia, restlessness, cold extremities, gastrointestinal abnormalities and priapism, were reported in 15 studies, while bleeding was recorded in 2 patients in the same study.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “The risk of tuberculosis infection in Saudi patients receiving adalimumab, etanercept, and tocilizumab therapy. METHODS: A retrospective cohort study extending over 2 years follow-up for all patients receiving Adalimumab, Etanercept and Tocilizumab for various clinical indications in a tertiary care center in Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Comprehensive Molecular Evaluation of HNF-1 Alpha, miR-27a, and miR-146 Gene Variants and Their Link with Predisposition and Progression in Type 2 Diabetes Patients. The objective of the present study was to examine the associations between MiR-27a, MiR-146, and HNF-1 alpha single-nucleotide variations (SNVs) with T2D risk in the Saudi population. METHODOLOGY: We evaluated the association of SNVs of miR-27a rs895819 A>G, 146a-rs2910164 C>G, and HNF-1 alpha rs1169288 G>T (I27L) with the risk of T2D in Saudi patients with the Amplification Refractory Mutation System PCR (ARMS-PCR). To our knowledge, this is the first study to highlight the association between miR-27a, miR-146, and HNF-1 alpha SNVs and the risk of T2D in the Saudi population.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Association of SARS-CoV-2 Nucleocapsid Protein Mutations with Patient Demographic and Clinical Characteristics during the Delta and Omicron Waves. We analyzed 695 samples from patients with confirmed COVID-19 in Saudi Arabia between 1 April 2021, and 30 April 2022.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “A Unique Case of Deficiency of Adenosine Deaminase 2 Single in a Young Adult Patient. In this study, we present a case of a 24-year-old Saudi male who was admitted with symptomatic anemia, lightheadedness, exertional symptoms, and a history of fever (38.1 C) for one week. In conclusion, we present one of the first cases in Saudi Arabia of an adult patient diagnosed with DADA2 with a unique gene mutation.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “TMPRSS6 gene mutations in six Saudi families with iron refractory iron deficiency anemia. This is the first study to investigate TMPRSS6 gene mutation in six Saudi families of probands with iron deficiency anemia unresponsive to oral iron and partially responsive to parenteral iron administration. While the p.W73X variant was only found in 2 families, the p.V736A variant was found in all examined Saudi families with IRIDA. Given the evidence outlined for these six cases, future genotype-phenotype correlation studies in a large number of IRIDA patients in Saudi Arabia may be very informative for patient management, in addition to increasing knowledge of TMPRSS6 function during development as well as factors in the regulation of TMPRSS6 and its effect on iron levels in the body.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Assessment of the Prevalence and Incidence of COVID-19 in Saudi Arabia. It has spread rapidly all over the world, including Saudi Arabia, having a severe health emergency. SARS-CoV-2 belongs to the family of Coronaviridae, Betacoronavirus, Sarbecovirus subgenus, genome β. The SARS-CoV-2 variants have caused significant morbidity and mortality worldwide and in Saudi Arabia as well.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Diabetic Retinopathy Screening Using Non-Mydriatic Fundus Camera in Primary Health Care Settings - A Multicenter Study from Saudi Arabia. BACKGROUND: Screening of diabetic retinopathy (DR) using the current digital imaging facilities in a primary health care setting is still in its early stages in Saudi Arabia. This study aims to reduce the risk of vision impairment and blindness among known diabetic people through early identification by general practitioners (GP) in a primary health care setting in Saudi Arabia. METHODS: A hospital-based, six-month cross-sectional study was conducted, and the participants were type 2 diabetic adults from the diabetic registries of seven rural PHCs, in Saudi Arabia. The study highlights the need for early DR screening programs in the rural areas of Saudi Arabia to facilitate early identification of the condition and to lessen impact of blindness due to diabetes.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Management of Patients with Alagille Syndrome Undergoing Living Donor Liver Transplantation: A Report of 2 Cases. AGS in a liver transplant setting is particularly rare in Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Incidence, risk factors, and whole-genome sequence of SARs-CoV-2 and influenza virus among the Egyptian pilgrims returning from Umrah mass gathering in Saudi Arabia, April-May 2022. Incidence calculated, descriptive data analysis performed, and SARS-CoV-2 patients were compared to negatively tested participants using chi2 and p value< 0.05.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Novel Heterozygous Variants in the HLA-DRB1 Gene in a Saudi Family With Early-Onset Familial Multiple Sclerosis: Therapeutic Failure and Success. The aim of this article is to report a unique case of familial MS from Saudi Arabia with 2 novel variants in the HLA-DRB1 gene that may contribute to the pathogenesis. This family work-up illustrates the importance of genetic testing in identifying variants associated with familial MS, especially if more than 2 members of the same family are affected.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Association of Vitamin D Deficiency and Vitamin D Receptor Genetic Variants With Coronary Artery Disease in Type 2 Diabetic Saudi Patients.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “SARS-CoV-2 genomes from Saudi Arabia implicate nucleocapsid mutations in host response and increased viral load. Here, we sequenced 892 SARS-CoV-2 genomes collected from patients in Saudi Arabia from March to August 2020.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “We describe 2 unusual cases of nutritional iron deficiency anemia with profound low level of hemoglobin around 1 g/dl, with similar diagnosis and different hospital course. CASE REPORT First case: A 20-month-old Saudi boy presented with symptoms of acute gastroenteritis. Second case: A 26-month-old Saudi girl presented with complaints of severe pallor and fatigability for 2 months, with critical result of extreme low level of hemoglobin 1.2 g/dl.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “SARS-CoV-2 Reinfection Rate and Outcomes in Saudi Arabia: A National Retrospective Study. BACKGROUND: The characterization of reinfection with SARS-CoV-2 has been a subject of concern and controversy, especially with the surge of infections with highly transmissible variants worldwide. RESULTS: Between March 2020 and December 2021, 4454 reinfected participants were identified in Saudi Arabia (0.8%, 95% confidence interval [CI] 0.7-0.8).” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Group-specific component exon 11 haplotypes (D432E and T436K) and risk of albuminuria in type 2 diabetes mellitus patients. We aimed to investigate the association of GC variants and protein expression level with T2DM and diabetic nephropathy (DN) in Saudi patients.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Vitamin D Serum Levels in Type 2 Diabetic Patients: A Cross-Sectional Study. In this study, we aimed to determine the prevalence of vitamin D deficiency in T2DM patients in Saudi Arabia. Methods This was a retrospective cross-sectional study conducted at the King Faisal University Health Centre in Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Emergence of SARS-CoV-2 variants has been a subject of considerable debate regarding vaccines effectiveness. This study was conducted to assess COVID-19 vaccine uptake and hesitancy among the Saudi Arabian population during the emergence of SARS-CoV-2 Delta variant.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Investigation of Isocitrate Dehydrogenase 1 and 2 Mutations in Acute Leukemia Patients in Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Methods: In this study, we cloned, for the first time, Vpx gene from a HIV-2 infected patient and found up to 30% sequence variation compared to known HIV-2 strains. We then analyzed the role of SAMHD1 protein expression in transfected THP-1 and U937 cells by transfecting with the Vpx gene derived from SIVmac, HIV-2 from the NIH sample as well as HIV-2 from a Saudi patient.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “An 11-Year-Old Saudi Arabian Girl Who Presented with Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with SARS-CoV-2 Infection with Coronary Artery Aneurysm and Cardiac Involvement: A Case Report. This report aims to describe a case of MIS-C in an 11-year-old Saudi Arabian girl who presented with coronary artery aneurysm and cardiac involvement. CASE REPORT We describe an 11-year-old Saudi girl who was asymptomatic for 3 weeks after contracting SARS-CoV-2. The increasing number of emerging SARS-CoV-2 variants that affect children supports the importance of RT-PCR for the COVID-19 diagnostic test for children with multisystem or cardiovascular inflammation, which may guide the most appropriate clinical management of the variants of MIS-C.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “METHODS: Twelve patients from 7 Turkish and 2 Saudi families were investigated.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Correction to: Apolipoprotein C3Gene Variants and Risk of Developing Type 2 Diabetes in Saudi Subjects by Alharbi KK, Hussain T, Alharbi FK, Tabassum SN, Mohammed AA, Gambhir D, and Khan IA.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Behçet's disease presentations and care outcomes in a tertiary hospital in south-western Saudi Arabia. AIM: To study the clinical presentations of Behçet's disease in patients visiting a tertiary hospital in south-western Saudi Arabia. PATIENTS AND METHODS: Forty-seven patients with Behçet's disease attending the Rheumatology Department at Asser Central Hospital, Saudi Arabia were recruited into the study. Only 2 patients died during the study period. CONCLUSION: Behçet's disease showed higher male predominance in south-western Saudi Arabia, similar to other Middle-Eastern countries.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “We report a Saudi family with a very rare form of autosomal dominant PME. METHODS: We included two patients from Saudi Arabia with a presumptive clinical diagnosis of PME. The patients were from a family with an affected mother I-2 and two affected siblings proband II-3 and II-4 (a girl and a boy).” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Association of Vitamin D deficiency and Vitamin D Receptor Gene Polymorphisms with Type 2 diabetes mellitus Saudi patients. SUBJECTS AND METHODS: One hundred T2DM Saudi male patients were included in this study and one hundred healthy Saudi men were used as control.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Association of Circulating Vitamin D, VDBP, and Vitamin D Receptor Expression with Severity of Diabetic Nephropathy in a Group of Saudi Type 2 Diabetes Mellitus Patients. We aimed to analyze the circulating levels of total 25-hydroxy vitamin D (25-OHD), vitamin D receptor (VDR) transcript and VD-binding protein (VDBP) in a sample of Saudi T2DM and to correlate these profiles with diabetic nephropathy and insulin resistance. CONCLUSIONS: The study findings suggest a potential role of vitamin D metabolic players in DN, with a special concern regarding serum VDPB as a putative predictor of DN severity in type 2 DM Saudi patients.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Here, We report on 12-month-old and 30-month-old girls from 2 unrelated Saudi families with typical presentations of PRUNE syndrome.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “In Saudi Arabia and other Arab countries, several studies estimated the prevalence of DR ranging from 30 - 40%. AIM: To assess the DR knowledge and its association with diabetes control among Type 2 diabetic patients.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Synaptosomal Protein of 25 kDa (Snap25) Polymorphisms Associated with Glycemic Parameters in Type 2 Diabetes Patients. Genomic DNA from 1019 Saudi individuals (489 confirmed T2DM and 530 controls) was genotyped for SNPs rs363039, rs363043, and rs363050 in Snap25 using the TaqMan Genotyping Assay.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Lack of Association between Angiotensin Converting Enzyme I/D Polymorphism and Unexplained Recurrent Miscarriage in Saudi Arabia. We initiated this study to determine the association, if any, between the I/D polymorphism of ACE gene and RM in Saudi females. METHOD: This study was conducted on 61 Saudi females suffering from RM (mean age: 34.1±6.2 years; range 15-45) attending clinics at King Khalid University Hospital, and 59 age matched females who had at least 2 children, as controls. However, this association was not apparent in the Saudi females.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Apolipoprotein C3 Gene Variants and Risk of Developing Type 2 Diabetes in Saudi Subjects. Considering the high prevalence of T2DM in Saudi Arabia, we sought to examine the possible association of ApoC3 gene variants with diabetes risk in Saudi population. CONCLUSIONS: Thus, 3238C>G polymorphism of ApoC3 gene appears to augment the propensity to develop T2DM, while -482C>T to negatively affect lipid metabolism in Saudi subjects.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Parkinson's Disease in Saudi Patients: A Genetic Study. Exon/intron dosage alterations in PARKIN were detected and confirmed in 2 cases. Our study suggests that mutations in the ORF of the screened genes are not a common cause of PD in Saudi population; however, these findings by no means exclude the possibility that other genetic events such as gene expression/dosage alteration may be more common nor does it eliminate the possibility of the involvement of novel genes.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Association between FTO, MC4R, SLC30A8, and KCNQ1 gene variants and type 2 diabetes in Saudi population. In the present study, we examined the association between variants in fat mass- and obesity-associated [rs9939609 (A/T)], melanocortin 4 receptor [rs17782313 (C/T), and rs12970134 (A/G)], SLC30A8 [rs13266634 (C/T)], and a member of the potassium voltage-gated channels [rs2237892(C/T)] genes in diabetes patients from Saudi Arabia. Minor allele frequency of the 4 variants tested was comparable between type 2 diabetes cases and controls. Our data indicate that the SLC30A8 polymorphisms are associated with type 2 diabetes in the Saudi population. There is no evidence supporting an association between variants in the fat mass- and obesity-associated and melanocortin 4 receptor, and a member of the potassium voltage-gated channels genes and type 2 diabetes in the Saudi population.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Inflammatory markers and haptoglobin polymorphism in Saudi with non-insulin-dependent diabetes mellitus. We designed the present study to investigate the frequency distribution of Hp phenotypes among Saudi with non-insulin-dependent diabetes mellitus compared to healthy nondiabetic subjects. METHODS: In the present case-control study, we enrolled 60 type 2 diabetic patients as the study group and 60 healthy subjects as the control group. Hp 2-1 was the predominant phenotype among Saudi type 2 diabetics as well as healthy subjects.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Prevalence of hearing loss among Saudi type 2 diabetic patients.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Prevalence of hearing loss among Saudi type 2 diabetic patients. OBJECTIVE: To compare hearing impairment and audiometric shapes associated with type 2 diabetes mellitus (T2DM) with an age-matched control group in the Saudi population.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Human immunodeficiency virus type 2 in two Saudi families. We report cases in two Saudi families with HIV-2 infection and AIDS, resulting in death of the index cases-the husbands, while the wives and a daughter were maintained on antiretroviral therapy.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Founder heterozygous P23T CRYGD mutation associated with cerulean (and coralliform) cataract in 2 Saudi families. PURPOSE: To assess for gammaD-crystallin (CRYGD) mutation in 2 Saudi patients with cerulean cataract and in a brother of one of the patients who had coralliform cataract. CONCLUSIONS: This first report of p.P23T CRYGD mutation underlying cerulean cataract in the Saudi population strongly supports the mutation's relation with the phenotype.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “METHODS: In this study, we compared 2 populations of patients from Iraq and Saudi Arabia, both of whom underwent splenectomy for thalassaemia. All patients from Saudi Arabia were given a preoperative pneumococcal vaccine and underwent total splenectomy after about 4 weeks. One death over a 12-year period was reported in the 22 patients from Saudi Arabia.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Cerebrotendinous xanthomatosis in a Saudi Arabian family-genotyping and long-term follow-up. A Saudi Arabian family is described in which there were 2 siblings with typical features of cerebral xanthomatosis CTX including premature cataracts, xanthomata of the Achilles tendons, neuro-psychiatric disturbances, and atherosclerosis. The 2 patients were homozygous for a point mutation in the mitochondrial 27-hydroxylase gene CYP27A1, OMIM 606530 located in the splice site of intron 6, where G was exchanged for A IVS6+1G>A.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “AIM: To assess the severity of the disease and its response to therapy in patients referred to a tertiary care referral centre in Gassim region, Kingdom of Saudi Arabia (KSA). Endoscopically UC was graded as 2 in three patients (9%), 3 in 21 patients (59%) and 4 in ten patients (29%).” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Diabetes mellitus and cystic fibrosis in 2 Saudi siblings. We present the first reported case of insulin dependent diabetes mellitus (IDDM) and CF in 2 siblings of the same family.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “The association of leukocyte adhesion defect type I and persistent hyperinsulinemic hypoglycemia of infancy in a Saudi Arabian family. The authors describe 2 female sibling infants diagnosed with leukocyte adhesion defects CD11 and CD18.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “The group consisted of 28 SS, 8 Sbeta-thal, and 2 SD patients all in steady state; 5 SS patients were studied during 7 episodes of painful crisis. Most (82%) were homozygous for the Saudi Arabia/India haplotype and had elevated Hb F levels ranging from 15% to 35%.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “The incidence of HI in the Caucasian population is estimated at 1:50,000, however an apparent increased incidence among Ashkenazi Jews and Saudi Arabian Arabs has been reported. In this study, we evaluated disease-associated chromosomes from 41 Ashkenazi Jewish and 2 non-Jewish HI patients carrying the 3992-9g-->a mutation by assessing haplotypes defined by nine common single nucleotide polymorphisms (SNPs), six in the SUR1 gene, and three in the KIR6.2 gene.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Robinow syndrome and Crigler-Najar syndrome were encountered in 2 Saudi offspring of first cousins. The parents lost 2 previous children at age 2 months with progressive jaundice but without fetal facial characteristics.” | 0.95 | saudi_context_rules_v1 |
| population | Saudi Arabia | “Double heterozygote leftward/rightward deletion type alpha-thalassaemia in Saudi Arabs. Restriction endonucleases have been used for the investigation of deletion type alpha-thalassaemias in the Saudi population. Using Bgl II digestion, we diagnosed 2 cases with 15.8- and 7.0-kb alpha-globin gene fragments. This is the first report of heterozygous leftward/rightward deletion in the Saudi population.” | 0.95 | saudi_context_rules_v1 |