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Gene profile

IFT27

HGNC:18626 · SaudiVarKB evidence summary derived from retained literature mentions.

2Gene mentions
2Publications
15Linked variants
2Associated phenotypes

Associated phenotypes

Co-mentioned in IFT27 publications
PhenotypeIdentifierArticlesMentions
Bardet-Biedl syndrome22
obesityHP:000151311

Linked variants

Variants normalized to IFT27
VariantHGVS / rsIDArticlesMentions
c.94C>Tc.94C>T11
p.Gln32Terp.Gln32Ter11
c.160A>Tc.160A>T11
p.Lys54Terp.Lys54Ter11
c.720C>Ac.720C>A11
p.Cys240Terp.Cys240Ter11
c.505A>Tc.505A>T11
p.Lys169Terp.Lys169Ter11
c.775delAc.775delA11
c.1339G>Ac.1339G>A11
p.Ala447Thrp.Ala447Thr11
c.951+1G>Ac.951+1G>A11
c.119C>Gc.119C>G11
p.Ser40*p.Ser40*11
c.196delAc.196delA11

Population context

Reported in the same publications
Country / regionGroupCohortArticles
Not specified1
Not specified101

Supporting publications

2 records
  1. 2023Biallelic Variants in Seven Different Genes Associated with Clinically Suspected Bardet-Biedl Syndrome.GenesPubMed ↗
  2. 2014IFT27, encoding a small GTPase component of IFT particles, is mutated in a consanguineous family with Bardet-Biedl syndrome.Human molecular geneticsPubMed ↗