← New search
Gene profile

STAT6

HGNC:11368 · SaudiVarKB evidence summary derived from retained literature mentions.

15Gene mentions
15Publications
7Linked variants
8Associated phenotypes

Associated phenotypes

Co-mentioned in STAT6 publications
PhenotypeIdentifierArticlesMentions
atopic dermatitis22
asthma22
epilepsyHP:000125011
hearing lossHP:000036511
neurodevelopmental disorderHP:001275911
pre-eclampsia11
multiple sclerosis11
congenital myopathy11

Linked variants

Variants normalized to STAT6
VariantHGVS / rsIDArticlesMentions
I50V22
G2964A11
G2946A11
Q576R11
E318G11
L365F11
R562H11

Population context

Reported in the same publications
Country / regionGroupCohortArticles
Not specified171
Not specified2851
Not specified951
Saudi Arabia1501
Not specified491
Not specified1481

Supporting publications

15 records
  1. 2026GLI1-fusion neoplasm of the tongue: report of a pediatric case associated with SHOX deficiency disorder.Virchows Archiv : an international journal of pathologyPubMed ↗
  2. 2025Inflammatory myopathy with abundant macrophage [IMAM]: Systemic analysis and pathological approach to distinguish it from dermatomyositis.Journal of neuromuscular diseasesPubMed ↗
  3. 2025Unraveling the Role of THRIL/miR-137 in Fine-Tuning the Immunological Transcriptional Loop STAT4/STAT6/GATA3 in Multiple Sclerosis: Implications on Neurological Complications and Disease Subtypes.ACS chemical neurosciencePubMed ↗
  4. 2025Functionally graded scaffold with M2 macrophage-derived LncRNA-Encoded peptide: Mechanistic and therapeutic evaluation for rotator cuff repair.Bioactive materialsPubMed ↗
  5. 2025Malignant solitary fibrous tumor of the temporal bone with NAB2 ex6::STAT6 ex16 fusion: a case report with literature review.World journal of surgical oncologyPubMed ↗
  6. 2024Allergic Airway Inflammation Emerges from Gut Inflammation and Leakage in Mouse Model of Asthma.Advanced biologyPubMed ↗
  7. 2024IL-4-STAT6 axis amplifies histamine-induced vascular endothelial dysfunction and hypovolemic shock.The Journal of allergy and clinical immunologyPubMed ↗
  8. 2023A new machine learning based computational framework identifies therapeutic targets and unveils influential genes in pancreatic islet cells.GenePubMed ↗
  9. 2023Signal Transducer and Activator of Transcription 6 Changes and Protein Frustration by Single Amino Acid Substitutions: Implications for Cancer Progression.Omics : a journal of integrative biologyPubMed ↗
  10. 2023Modeling the Effects of Cypermethrin Toxicity on Ovalbumin-Induced Allergic Pneumonitis Rats: Macrophage Phenotype Differentiation and p38/STAT6 Signaling Are Candidate Targets of Pirfenidone Treatment.CellsPubMed ↗
  11. 2021Association of endothelial nitric oxide synthase gene variants with preeclampsia.Reproductive healthPubMed ↗
  12. 2020Orbital solitary fibrous tumors: a multi-centered histopathological and immunohistochemical analysis with radiological description.Annals of Saudi medicinePubMed ↗
  13. 2016Gene Polymorphism of Interleukin-4, Interleukin-4 Receptor and STAT6 in Children with Atopic Dermatitis in Taif, Saudi Arabia.Immunological investigationsPubMed ↗
  14. 2014Association between genes encoding components of the IL-4/IL-4 receptor pathway and dermatitis in children.GenePubMed ↗
  15. 2013Genome-wide meta-analysis identifies new susceptibility loci for migraine.Nature geneticsPubMed ↗