61+ results for “Familial hypercholesterolemia”

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Familial hypercholesterolemia
Phenotype · HP:0003124 · 165 articles

Publications

Matches:
familial hypercholesterolemia “We examined 74 genes curated from the Genomics England PanelApp, focusing on familial hypercholesterolemia (FH), cardiac arrhythmias (CA), and pulmonary arterial hypertension (PAH), ultimately detecting 8,251 variants.”
PAH “We examined 74 genes curated from the Genomics England PanelApp, focusing on familial hypercholesterolemia (FH), cardiac arrhythmias (CA), and pulmonary arterial hypertension (PAH), ultimately detecting 8,251 variants.”
Matches:
familial hypercholesterolemia “The high prevalence of traditional risk factors, including dyslipidemia, obesity, diabetes, hypertension, smoking, and physical inactivity, together with genetic predisposition and familial hypercholesterolemia, contributes substantially to earlier disease onset.”
hypertension “The high prevalence of traditional risk factors, including dyslipidemia, obesity, diabetes, hypertension, smoking, and physical inactivity, together with genetic predisposition and familial hypercholesterolemia, contributes substantially to earlier disease onset.”
Matches:
familial hypercholesterolemia “Traditional cardiovascular risk factors and their association with atherosclerotic cardiovascular disease in homozygous familial hypercholesterolemia: A cross-sectional analysis from the HICC registry.”
coronary artery disease “This study aimed to determine the prevalence of traditional coronary artery disease (CAD) risk factors-hypertension, diabetes, smoking, and obesity-and their associations with CAD in HoFH.”
Matches:
familial hypercholesterolemia “Global survey of genetic testing methods for familial hypercholesterolemia.”
LDLR “BACKGROUND AND AIMS: Familial hypercholesterolemia (FH), primarily caused by pathogenic LDLR, APOB, or PCSK9 variants, results in elevated LDL-C and increased cardiovascular risk.”
Matches:
familial hypercholesterolemia “Both drug classes are well tolerated across diverse patient populations, including those with high or very high-risk, familial hypercholesterolemia (FH), recent acute coronary syndrome (ACS), or statin intolerance.”
PCSK9 “Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)-targeted therapies, which include monoclonal antibodies (evolocumab, alirocumab) and small interfering RNA (inclisiran), offer potent LDL-C lowering that can help address this gap.”
Matches:
familial hypercholesterolemia “Correction: Untargeted metabolomics reveals distinct biomarkers and metabolic alterations in familial and non-genetic hypercholesterolemia in Saudi patients. [This corrects the article DOI: 10.3389/fmed.2025.1670282.].”
Saudi Arabia “Correction: Untargeted metabolomics reveals distinct biomarkers and metabolic alterations in familial and non-genetic hypercholesterolemia in Saudi patients. [This corrects the article DOI: 10.3389/fmed.2025.1670282.].”
Matches:
familial hypercholesterolemia “Severe left main and ostial right coronary obstruction with supra aortic valve atherosclerotic stenosis in a 16 Year old patient with familial hypercholesterolemia: A case report.”

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