Gene

MTHFR

HGNC: HGNC:7436 | GeneCards: MTHFR
Saudi human-genetics coreAll Saudi-affiliated records

Overview

Approved name
Cytogenetic location
-
Locus type
-
In SaudiVarKB
32 articles, 32 mentions

Synonyms

None recorded

External resources

ClinVar ↗PubMed ↗
32Publications20Co-reported phenotypes7Reported variants
0ClinVar pathogenic / likely pathogenic
4Saudi regionsOpenLiterature network

Co-reported phenotypes

Phenotypes named in the same articles as MTHFR. Co-mention, not a proven association.

PhenotypeArticlesEvidence
obesity4View sentences
hypertension3View sentences
sickle cell disease3View sentences
autism spectrum disorder2View sentences
diabetes mellitus2View sentences
epilepsy2View sentences
recurrent pregnancy loss2View sentences
colorectal cancer1View sentences
coronary artery disease1View sentences
dyslipidemia1View sentences
glucose-6-phosphate dehydrogenase deficiency1View sentences
infertility1View sentences
lung cancer1View sentences
lymphoma1View sentences
metabolic syndrome1View sentences
neurodevelopmental disorder1View sentences
primary congenital glaucoma1View sentences
renal failure1View sentences
stroke1View sentences
thyroid cancer1View sentences

Reported variants

Variants linked to MTHFR through dbSNP or LitVar2. ClinVar status is shown for core-subset variants.

VariantrsIDArticlesClinVar
C677T-7-
rs1801133rs18011334-
A1298C-3-
rs1801131rs18011312-
677C>T-1-
A1578G-1-
c.1298A>C-1-

Saudi regions

Regions or cities named in the abstracts of articles that mention MTHFR.

RegionArticles
Qassim5
Eastern Province2
Jeddah2
Tabuk1